Metabolic reprogramming during the Trypanosoma brucei life cycle [version 2; referees: 4 approved]

by Terry K. Smith, Frédéric Bringaud, Derek P. Nolan, Luisa M. Figueiredo
Published 2017-05-01

Metabolic reprogramming during the Trypanosoma brucei life cycle [version 1; referees: 4 approved]

by Terry K. Smith, Frédéric Bringaud, Derek P. Nolan, Luisa M. Figueiredo
Published 2017-05-01

The Uptake and Metabolism of Amino Acids, and Their Unique Role in the Biology of Pathogenic Trypanosomatids

by Letícia Marchese, Janaina de Freitas Nascimento, Flávia Silva Damasceno, Frédéric Bringaud, Paul A. M. Michels, Ariel Mariano Silber
Published 2018-04-01

Confining Trypanosoma brucei in emulsion droplets reveals population variabilities in division rates and improves in vitro cultivation

by Simone H. Oldenburg, Lionel Buisson, Thomas Beneyton, Deniz Pekin, Magali Thonnus, Frédéric Bringaud, Loïc Rivière, Jean-Christophe Baret
Published 2021-09-01

Deletion of transketolase triggers a stringent metabolic response in promastigotes and loss of virulence in amastigotes of Leishmania mexicana.

by Julie Kovářová, Andrew W Pountain, David Wildridge, Stefan Weidt, Frédéric Bringaud, Richard J S Burchmore, Fiona Achcar, Michael P Barrett
Published 2018-03-01

Fatty acid oxidation participates in resistance to nutrient-depleted environments in the insect stages of Trypanosoma cruzi.

by Rodolpho Ornitz Oliveira Souza, Flávia Silva Damasceno, Sabrina Marsiccobetre, Marc Biran, Gilson Murata, Rui Curi, Frédéric Bringaud, Ariel Mariano Silber
Published 2021-04-01

Members of a large retroposon family are determinants of post-transcriptional gene expression in Leishmania.

by Frédéric Bringaud, Michaela Müller, Gustavo Coutinho Cerqueira, Martin Smith, Annie Rochette, Najib M A El-Sayed, Barbara Papadopoulou, Elodie Ghedin
Published 2007-09-01

Regulation of Trypanosoma brucei Total and Polysomal mRNA during Development within Its Mammalian Host.

by Paul Capewell, Stephanie Monk, Alasdair Ivens, Paula Macgregor, Katelyn Fenn, Pegine Walrad, Frederic Bringaud, Terry K Smith, Keith R Matthews
Published 2013-01-01

Triacylglycerol Storage in Lipid Droplets in Procyclic Trypanosoma brucei.

by Stefan Allmann, Muriel Mazet, Nicole Ziebart, Guillaume Bouyssou, Laetitia Fouillen, Jean-William Dupuy, Marc Bonneu, Patrick Moreau, Frédéric Bringaud, Michael Boshart
Published 2014-01-01

Revisiting the central metabolism of the bloodstream forms of Trypanosoma brucei: production of acetate in the mitochondrion is essential for parasite viability.

by Muriel Mazet, Pauline Morand, Marc Biran, Guillaume Bouyssou, Pierrette Courtois, Sylvie Daulouède, Yoann Millerioux, Jean-Michel Franconi, Philippe Vincendeau, Patrick Moreau, Frédéric Bringaud
Published 2013-01-01

Proline Metabolism is Essential for Trypanosoma brucei brucei Survival in the Tsetse Vector.

by Brian S Mantilla, Letícia Marchese, Aitor Casas-Sánchez, Naomi A Dyer, Nicholas Ejeh, Marc Biran, Frédéric Bringaud, Michael J Lehane, Alvaro Acosta-Serrano, Ariel M Silber
Published 2017-01-01

Glycerol supports growth of the Trypanosoma brucei bloodstream forms in the absence of glucose: Analysis of metabolic adaptations on glycerol-rich conditions.

by Erika Pineda, Magali Thonnus, Muriel Mazet, Arnaud Mourier, Edern Cahoreau, Hanna Kulyk, Jean-William Dupuy, Marc Biran, Cyril Masante, Stefan Allmann, Loïc Rivière, Brice Rotureau, Jean-Charles Portais, Frédéric Bringaud
Published 2018-11-01

De novo biosynthesis of sterols and fatty acids in the Trypanosoma brucei procyclic form: Carbon source preferences and metabolic flux redistributions.

by Yoann Millerioux, Muriel Mazet, Guillaume Bouyssou, Stefan Allmann, Tiila-Riikka Kiema, Eloïse Bertiaux, Laetitia Fouillen, Chandan Thapa, Marc Biran, Nicolas Plazolles, Franziska Dittrich-Domergue, Aline Crouzols, Rik K Wierenga, Brice Rotureau, Patrick Moreau, Frédéric Bringaud
Published 2018-05-01

Procyclic trypanosomes recycle glucose catabolites and TCA cycle intermediates to stimulate growth in the presence of physiological amounts of proline.

by Oriana Villafraz, Marc Biran, Erika Pineda, Nicolas Plazolles, Edern Cahoreau, Rodolpho Ornitz Oliveira Souza, Magali Thonnus, Stefan Allmann, Emmanuel Tetaud, Loïc Rivière, Ariel M Silber, Michael P Barrett, Alena Zíková, Michael Boshart, Jean-Charles Portais, Frédéric Bringaud
Published 2021-03-01

Gluconeogenesis is essential for trypanosome development in the tsetse fly vector.

by Marion Wargnies, Eloïse Bertiaux, Edern Cahoreau, Nicole Ziebart, Aline Crouzols, Pauline Morand, Marc Biran, Stefan Allmann, Jane Hubert, Oriana Villafraz, Yoann Millerioux, Nicolas Plazolles, Corinne Asencio, Loïc Rivière, Brice Rotureau, Michael Boshart, Jean-Charles Portais, Frédéric Bringaud
Published 2018-12-01

Probing the metabolic network in bloodstream-form Trypanosoma brucei using untargeted metabolomics with stable isotope labelled glucose.

by Darren J Creek, Muriel Mazet, Fiona Achcar, Jana Anderson, Dong-Hyun Kim, Ruwida Kamour, Pauline Morand, Yoann Millerioux, Marc Biran, Eduard J Kerkhoven, Achuthanunni Chokkathukalam, Stefan K Weidt, Karl E V Burgess, Rainer Breitling, David G Watson, Frédéric Bringaud, Michael P Barrett
Published 2015-03-01

The streamlined genome of Phytomonas spp. relative to human pathogenic kinetoplastids reveals a parasite tailored for plants.

by Betina M Porcel, France Denoeud, Fred Opperdoes, Benjamin Noel, Mohammed-Amine Madoui, Tansy C Hammarton, Mark C Field, Corinne Da Silva, Arnaud Couloux, Julie Poulain, Michael Katinka, Kamel Jabbari, Jean-Marc Aury, David A Campbell, Roxana Cintron, Nicholas J Dickens, Roberto Docampo, Nancy R Sturm, V Lila Koumandou, Sandrine Fabre, Pavel Flegontov, Julius Lukeš, Shulamit Michaeli, Jeremy C Mottram, Balázs Szöőr, Dan Zilberstein, Frédéric Bringaud, Patrick Wincker, Michel Dollet
Published 2014-02-01