The immunosuppressive agent mizoribine monophosphate is an inhibitor of the human RNA capping enzyme.

by Frédéric Picard-Jean, Isabelle Bougie, Satoshi Shuto, Martin Bisaillon
Published 2013-01-01

Transcriptional pausing at the translation start site operates as a critical checkpoint for riboswitch regulation

by Adrien Chauvier, Frédéric Picard-Jean, Jean-Christophe Berger-Dancause, Laurène Bastet, Mohammad Reza Naghdi, Audrey Dubé, Pierre Turcotte, Jonathan Perreault, Daniel A. Lafontaine
Published 2017-01-01

2'-O-methylation of the mRNA cap protects RNAs from decapping and degradation by DXO.

by Frédéric Picard-Jean, Carolin Brand, Maude Tremblay-Létourneau, Andréa Allaire, Maxime C Beaudoin, Simon Boudreault, Cyntia Duval, Julien Rainville-Sirois, Francis Robert, Jerry Pelletier, Brian J Geiss, Martin Bisaillon
Published 2018-01-01

Correction: 2'-O-methylation of the mRNA cap protects RNAs from decapping and degradation by DXO.

by Frédéric Picard-Jean, Carolin Brand, Maude Tremblay-Létourneau, Andréa Allaire, Maxime C Beaudoin, Simon Boudreault, Cyntia Duval, Julien Rainville-Sirois, Francis Robert, Jerry Pelletier, Brian J Geiss, Martin Bisaillon
Published 2018-01-01