The immunosuppressive agent mizoribine monophosphate is an inhibitor of the human RNA capping enzyme.

by Frédéric Picard-Jean, Isabelle Bougie, Satoshi Shuto, Martin Bisaillon
Published 2013-01-01

Conformational Restriction of Histamine with a Rigid Bicyclo[3.1.0]hexane Scaffold Provided Selective H₃ Receptor Ligands

by Mizuki Watanabe, Takaaki Kobayashi, Yoshihiko Ito, Shizuo Yamada, Satoshi Shuto
Published 2020-08-01

Resolvin E3 attenuates lipopolysaccharide-induced depression-like behavior in mice

by Satoshi Deyama, Kento Shimoda, Hiroyuki Ikeda, Hayato Fukuda, Satoshi Shuto, Masabumi Minami
Published 2018-09-01

Effects of Three Lipidated Oxytocin Analogs on Behavioral Deficits in CD38 Knockout Mice

by Stanislav M. Cherepanov, Shirin Akther, Tomoko Nishimura, Anna A. Shabalova, Akira Mizuno, Wataru Ichinose, Satoshi Shuto, Yasuhiko Yamamoto, Shigeru Yokoyama, Haruhiro Higashida
Published 2017-10-01

Lipo-oxytocin-1, a Novel Oxytocin Analog Conjugated with Two Palmitoyl Groups, Has Long-Lasting Effects on Anxiety-Related Behavior and Social Avoidance in CD157 Knockout Mice

by Akira Mizuno, Stanislav M. Cherepanov, Yusuke Kikuchi, Azam AKM Fakhrul, Shirin Akther, Kisaburo Deguchi, Toru Yoshihara, Katsuhiko Ishihara, Satoshi Shuto, Haruhiro Higashida
Published 2015-01-01

CD38 Structure-Based Inhibitor Design Using the N1-Cyclic Inosine 5'-Diphosphate Ribose Template.

by Christelle Moreau, Qun Liu, Richard Graeff, Gerd K Wagner, Mark P Thomas, Joanna M Swarbrick, Satoshi Shuto, Hon Cheung Lee, Quan Hao, Barry V L Potter
Published 2013-01-01

Novel Characteristics of Trypanosoma brucei Guanosine 5'-monophosphate Reductase Distinct from Host Animals.

by Tomoaki Bessho, Tetsuya Okada, Chihiro Kimura, Takahiro Shinohara, Ai Tomiyama, Akira Imamura, Mitsuru Kuwamura, Kazuhiko Nishimura, Ko Fujimori, Satoshi Shuto, Osamu Ishibashi, Bruno Kilunga Kubata, Takashi Inui
Published 2016-01-01

Molecular Determinants and Pharmacological Analysis for a Class of Competitive Non-transported Bicyclic Inhibitors of the Betaine/GABA Transporter BGT1

by Stefanie Kickinger, Stefanie Kickinger, Maria E. K. Lie, Akihiro Suemasa, Anas Al-Khawaja, Koichi Fujiwara, Mizuki Watanabe, Kristine S. Wilhelmsen, Christina B. Falk-Petersen, Bente Frølund, Satoshi Shuto, Gerhard F. Ecker, Petrine Wellendorph
Published 2021-09-01

Characterization of Imidazopyridine Compounds as Negative Allosteric Modulators of Proton-Sensing GPR4 in Extracellular Acidification-Induced Responses.

by Ayaka Tobo, Masayuki Tobo, Takashi Nakakura, Masashi Ebara, Hideaki Tomura, Chihiro Mogi, Dong-Soon Im, Naoya Murata, Atsushi Kuwabara, Saki Ito, Hayato Fukuda, Mitsuhiro Arisawa, Satoshi Shuto, Michio Nakaya, Hitoshi Kurose, Koichi Sato, Fumikazu Okajima
Published 2015-01-01