Mouse Models of Aneuploidy

by Olivia Sheppard, Frances K. Wiseman, Aarti Ruparelia, Victor L. J. Tybulewicz, Elizabeth M. C. Fisher
Published 2012-01-01

The effects of Cstb duplication on APP/amyloid-β pathology and cathepsin B activity in a mouse model.

by Yixing Wu, Heather T Whittaker, Suzanna Noy, Karen Cleverley, Veronique Brault, Yann Herault, Elizabeth M C Fisher, Frances K Wiseman
Published 2021-01-01

The integration site of the APP transgene in the J20 mouse model of Alzheimer’s disease [version 1; referees: 1 approved, 2 approved with reservations]

by Justin L. Tosh, Matthew Rickman, Ellie Rhymes, Frances E. Norona, Emma Clayton, Lennart Mucke, Adrian M. Isaacs, Elizabeth M.C. Fisher, Frances K. Wiseman
Published 2017-09-01

The integration site of the APP transgene in the J20 mouse model of Alzheimer’s disease [version 2; referees: 1 approved, 2 approved with reservations]

by Justin L. Tosh, Matthew Rickman, Ellie Rhymes, Frances E. Norona, Emma Clayton, Lennart Mucke, Adrian M. Isaacs, Elizabeth M.C. Fisher, Frances K. Wiseman
Published 2018-10-01

Altered Hippocampal-Prefrontal Neural Dynamics in Mouse Models of Down Syndrome

by Pishan Chang, Daniel Bush, Stephanie Schorge, Mark Good, Tara Canonica, Nathanael Shing, Suzanna Noy, Frances K. Wiseman, Neil Burgess, Victor L.J. Tybulewicz, Matthew C. Walker, Elizabeth M.C. Fisher
Published 2020-01-01

Plasma biomarkers for amyloid, tau, and cytokines in Down syndrome and sporadic Alzheimer’s disease

by Carla M. Startin, Nicholas J. Ashton, Sarah Hamburg, Rosalyn Hithersay, Frances K. Wiseman, Kin Y. Mok, John Hardy, Alberto Lleó, Simon Lovestone, Lucilla Parnetti, Henrik Zetterberg, Abdul Hye, LonDownS Consortium, André Strydom
Published 2019-03-01

Publisher Correction: Genetic dissection of down syndrome‑associated alterations in APP/amyloid‑β biology using mouse models

by Justin L. Tosh, Elena R. Rhymes, Paige Mumford, Heather T. Whittaker, Laura J. Pulford, Sue J. Noy, Karen Cleverley, LonDownS Consortium, Matthew C. Walker, Victor L. J. Tybulewicz, Rob C. Wykes, Elizabeth M. C. Fisher, Frances K. Wiseman
Published 2021-07-01

Genetic dissection of down syndrome-associated alterations in APP/amyloid-β biology using mouse models

by Justin L. Tosh, Elena R. Rhymes, Paige Mumford, Heather T. Whittaker, Laura J. Pulford, Sue J. Noy, Karen Cleverley, LonDownS Consortium, Matthew C. Walker, Victor L. J. Tybulewicz, Rob C. Wykes, Elizabeth M. C. Fisher, Frances K. Wiseman
Published 2021-03-01

Fully-Automated μMRI Morphometric Phenotyping of the Tc1 Mouse Model of Down Syndrome.

by Nick M Powell, Marc Modat, M Jorge Cardoso, Da Ma, Holly E Holmes, Yichao Yu, James O'Callaghan, Jon O Cleary, Ben Sinclair, Frances K Wiseman, Victor L J Tybulewicz, Elizabeth M C Fisher, Mark F Lythgoe, Sébastien Ourselin
Published 2016-01-01

Substantially thinner internal granular layer and reduced molecular layer surface in the cerebellar cortex of the Tc1 mouse model of down syndrome – a comprehensive morphometric an...

by Da Ma, Manuel J. Cardoso, Maria A. Zuluaga, Marc Modat, Nick M. Powell, Frances K. Wiseman, Jon O. Cleary, Benjamin Sinclair, Ian F. Harrison, Bernard Siow, Karteek Popuri, Sieun Lee, Joanne A. Matsubara, Marinko V. Sarunic, Mirza Faisal Beg, Victor L.J. Tybulewicz, Elizabeth M.C. Fisher, Mark F. Lythgoe, Sebastien Ourselin
Published 2020-12-01

Massively parallel sequencing reveals the complex structure of an irradiated human chromosome on a mouse background in the Tc1 model of Down syndrome.

by Susan M Gribble, Frances K Wiseman, Stephen Clayton, Elena Prigmore, Elizabeth Langley, Fengtang Yang, Sean Maguire, Beiyuan Fu, Diana Rajan, Olivia Sheppard, Carol Scott, Heidi Hauser, Philip J Stephens, Lucy A Stebbings, Bee Ling Ng, Tomas Fitzgerald, Michael A Quail, Ruby Banerjee, Kai Rothkamm, Victor L J Tybulewicz, Elizabeth M C Fisher, Nigel P Carter
Published 2013-01-01