Age-Related Epigenetic Derangement upon Reprogramming and Differentiation of Cells from the Elderly

by Francesco Ravaioli, Maria G. Bacalini, Claudio Franceschi, Paolo Garagnani
Published 2018-01-01

Gene Editing Correction of a Urea Cycle Defect in Organoid Stem Cell Derived Hepatocyte-like Cells

by Mihaela Zabulica, Tomas Jakobsson, Francesco Ravaioli, Massoud Vosough, Roberto Gramignoli, Ewa Ellis, Olav Rooyackers, Stephen C. Strom
Published 2021-01-01

Applying hydrodynamic pressure to efficiently generate induced pluripotent stem cells via reprogramming of centenarian skin fibroblasts.

by Massoud Vosough, Francesco Ravaioli, Mihaela Zabulica, Miriam Capri, Paolo Garagnani, Claudio Franceschi, Julie Piccand, Marine R-C Kraus, Kristina Kannisto, Roberto Gramignoli, Stephen C Strom
Published 2019-01-01

Aging and Caloric Restriction Modulate the DNA Methylation Profile of the Ribosomal RNA Locus in Human and Rat Liver

by Noémie Gensous, Francesco Ravaioli, Chiara Pirazzini, Roberto Gramignoli, Ewa Ellis, Gianluca Storci, Miriam Capri, Stephen Strom, Ezio Laconi, Claudio Franceschi, Paolo Garagnani, Fabio Marongiu, Maria Giulia Bacalini
Published 2020-01-01

A Meta-Analysis of Brain DNA Methylation Across Sex, Age, and Alzheimer's Disease Points for Accelerated Epigenetic Aging in Neurodegeneration

by Camilla Pellegrini, Chiara Pirazzini, Claudia Sala, Luisa Sambati, Luisa Sambati, Igor Yusipov, Alena Kalyakulina, Francesco Ravaioli, Katarzyna M. Kwiatkowska, Danielle F. Durso, Mikhail Ivanchenko, Daniela Monti, Raffaele Lodi, Raffaele Lodi, Claudio Franceschi, Pietro Cortelli, Pietro Cortelli, Paolo Garagnani, Paolo Garagnani, Paolo Garagnani, Paolo Garagnani, Maria Giulia Bacalini
Published 2021-03-01