Quinolin-6-Yloxyacetamides Are Microtubule Destabilizing Agents That Bind to the Colchicine Site of Tubulin

by Ashwani Sharma, Gonzalo Sáez-Calvo, Natacha Olieric, Francisco de Asís Balaguer, Isabel Barasoain, Clemens Lamberth, J. Fernando Díaz, Michel O. Steinmetz
Published 2017-06-01

CTP promotes efficient ParB-dependent DNA condensation by facilitating one-dimensional diffusion from parS

by Francisco de Asis Balaguer, Clara Aicart-Ramos, Gemma LM Fisher, Sara de Bragança, Eva M Martin-Cuevas, Cesar L Pastrana, Mark Simon Dillingham, Fernando Moreno-Herrero
Published 2021-07-01

Crystal Structure of the Cyclostreptin-Tubulin Adduct: Implications for Tubulin Activation by Taxane-Site Ligands

by Francisco de Asís Balaguer, Tobias Mühlethaler, Juan Estévez-Gallego, Enrique Calvo, Juan Francisco Giménez-Abián, April L. Risinger, Erik J. Sorensen, Christopher D. Vanderwal, Karl-Heinz Altmann, Susan L. Mooberry, Michel O. Steinmetz, María Ángela Oliva, Andrea E. Prota, J. Fernando Díaz
Published 2019-03-01