Naloxonazine, an Amastigote-Specific Compound, Affects Leishmania Parasites through Modulation of Host-Encoded Functions.

by Géraldine De Muylder, Benoit Vanhollebeke, Guy Caljon, Alan R Wolfe, James McKerrow, Jean-Claude Dujardin
Published 2016-12-01

The Absence of C-5 DNA Methylation in <i>Leishmania donovani</i> Allows DNA Enrichment from Complex Samples

by Bart Cuypers, Franck Dumetz, Pieter Meysman, Kris Laukens, Géraldine De Muylder, Jean-Claude Dujardin, Malgorzata Anna Domagalska
Published 2020-08-01

A screen against Leishmania intracellular amastigotes: comparison to a promastigote screen and identification of a host cell-specific hit.

by Geraldine De Muylder, Kenny K H Ang, Steven Chen, Michelle R Arkin, Juan C Engel, James H McKerrow
Published 2011-07-01

Hit-to-lead development of the chamigrane endoperoxide merulin A for the treatment of African sleeping sickness.

by Gabriel Navarro, Supchar Chokpaiboon, Geraldine De Muylder, Walter M Bray, Sean C Nisam, James H McKerrow, Khanitha Pudhom, Roger G Linington
Published 2012-01-01

Macromolecular biosynthetic parameters and metabolic profile in different life stages of Leishmania braziliensis: Amastigotes as a functionally less active stage.

by Marlene Jara, Maya Berg, Guy Caljon, Geraldine de Muylder, Bart Cuypers, Denis Castillo, Ilse Maes, María Del Carmen Orozco, Manu Vanaerschot, Jean-Claude Dujardin, Jorge Arevalo
Published 2017-01-01

Multiplexed Spliced-Leader Sequencing: A high-throughput, selective method for RNA-seq in Trypanosomatids

by Bart Cuypers, Malgorzata A. Domagalska, Pieter Meysman, Géraldine de Muylder, Manu Vanaerschot, Hideo Imamura, Franck Dumetz, Thomas Wolf Verdonckt, Peter J. Myler, Gowthaman Ramasamy, Kris Laukens, Jean-Claude Dujardin
Published 2017-06-01

Targeting Ergosterol biosynthesis in Leishmania donovani: essentiality of sterol 14 alpha-demethylase.

by Laura-Isobel McCall, Amale El Aroussi, Jun Yong Choi, Debora F Vieira, Geraldine De Muylder, Jonathan B Johnston, Steven Chen, Danielle Kellar, Jair L Siqueira-Neto, William R Roush, Larissa M Podust, James H McKerrow
Published 2015-03-01

A Trypanosoma brucei kinesin heavy chain promotes parasite growth by triggering host arginase activity.

by Géraldine De Muylder, Sylvie Daulouède, Laurence Lecordier, Pierrick Uzureau, Yannick Morias, Jan Van Den Abbeele, Guy Caljon, Michel Hérin, Philippe Holzmuller, Silla Semballa, Pierrette Courtois, Luc Vanhamme, Benoît Stijlemans, Patrick De Baetselier, Michael P Barrett, Jillian L Barlow, Andrew N J McKenzie, Luke Barron, Thomas A Wynn, Alain Beschin, Philippe Vincendeau, Etienne Pays
Published 2013-10-01

Evolutionary genomics of epidemic visceral leishmaniasis in the Indian subcontinent

by Hideo Imamura, Tim Downing, Frederik Van den Broeck, Mandy J Sanders, Suman Rijal, Shyam Sundar, An Mannaert, Manu Vanaerschot, Maya Berg, Géraldine De Muylder, Franck Dumetz, Bart Cuypers, Ilse Maes, Malgorzata Domagalska, Saskia Decuypere, Keshav Rai, Surendra Uranw, Narayan Raj Bhattarai, Basudha Khanal, Vijay Kumar Prajapati, Smriti Sharma, Olivia Stark, Gabriele Schönian, Harry P De Koning, Luca Settimo, Benoit Vanhollebeke, Syamal Roy, Bart Ostyn, Marleen Boelaert, Louis Maes, Matthew Berriman, Jean-Claude Dujardin, James A Cotton
Published 2016-03-01