Functional genomics in sand fly-derived Leishmania promastigotes.

by Pedro J Alcolea, Ana Alonso, Ricardo Molina, Maribel Jiménez, Peter J Myler, Vicente Larraga
Published 2019-05-01

The role of medical structural genomics in discovering new drugs for infectious diseases.

by Wesley C Van Voorhis, Wim G J Hol, Peter J Myler, Lance J Stewart
Published 2009-10-01

Disclosing 3' UTR cis-elements and putative partners involved in gene expression regulation in Leishmania spp.

by Monica Cristina Terrão, Elton José Rosas de Vasconcelos, Tânia Aquino Defina, Peter J Myler, Angela Kaysel Cruz
Published 2017-01-01

The putative Leishmania telomerase RNA (LeishTER) undergoes trans-splicing and contains a conserved template sequence.

by Elton J R Vasconcelos, Vinícius S Nunes, Marcelo S da Silva, Marcela Segatto, Peter J Myler, Maria Isabel N Cano
Published 2014-01-01

A Phenotarget Approach for Identifying an Alkaloid Interacting with the Tuberculosis Protein Rv1466

by Yan Xie, Yunjiang Feng, Angela Di Capua, Tin Mak, Garry W. Buchko, Peter J. Myler, Miaomiao Liu, Ronald J. Quinn
Published 2020-03-01

Chromatin-Associated Protein Complexes Link DNA Base J and Transcription Termination in <i>Leishmania</i>

by Bryan C. Jensen, Isabelle Q. Phan, Jacquelyn R. McDonald, Aakash Sur, Mark A. Gillespie, Jeffrey A. Ranish, Marilyn Parsons, Peter J. Myler
Published 2021-02-01

An Arginine Deprivation Response Pathway Is Induced in Leishmania during Macrophage Invasion.

by Adele Goldman-Pinkovich, Caitlin Balno, Rona Strasser, Michal Zeituni-Molad, Keren Bendelak, Doris Rentsch, Moshe Ephros, Martin Wiese, Armando Jardim, Peter J Myler, Dan Zilberstein
Published 2016-04-01

Dramatic changes in gene expression in different forms of Crithidia fasciculata reveal potential mechanisms for insect-specific adhesion in kinetoplastid parasites.

by John N Filosa, Corbett T Berry, Gordon Ruthel, Stephen M Beverley, Wesley C Warren, Chad Tomlinson, Peter J Myler, Elizabeth A Dudkin, Megan L Povelones, Michael Povelones
Published 2019-07-01

Evolutionary Diversification of Host-Targeted <i>Bartonella</i> Effectors Proteins Derived from a Conserved FicTA Toxin-Antitoxin Module

by Tilman Schirmer, Tjaart A. P. de Beer, Stefanie Tamegger, Alexander Harms, Nikolaus Dietz, David M. Dranow, Thomas E. Edwards, Peter J. Myler, Isabelle Phan, Christoph Dehio
Published 2021-07-01

Multiplexed Spliced-Leader Sequencing: A high-throughput, selective method for RNA-seq in Trypanosomatids

by Bart Cuypers, Malgorzata A. Domagalska, Pieter Meysman, Géraldine de Muylder, Manu Vanaerschot, Hideo Imamura, Franck Dumetz, Thomas Wolf Verdonckt, Peter J. Myler, Gowthaman Ramasamy, Kris Laukens, Jean-Claude Dujardin
Published 2017-06-01

Discovery of a Natural Product That Binds to the <i>Mycobacterium tuberculosis</i> Protein Rv1466 Using Native Mass Spectrometry

by Ali R. Elnaas, Darren Grice, Jianying Han, Yunjiang Feng, Angela Di Capua, Tin Mak, Joseph A. Laureanti, Garry W. Buchko, Peter J. Myler, Gregory Cook, Ronald J. Quinn, Miaomiao Liu
Published 2020-05-01

Ligand co-crystallization of aminoacyl-tRNA synthetases from infectious disease organisms

by Spencer O. Moen, Thomas E. Edwards, David M. Dranow, Matthew C. Clifton, Banumathi Sankaran, Wesley C. Van Voorhis, Amit Sharma, Colin Manoil, Bart L. Staker, Peter J. Myler, Donald D. Lorimer
Published 2017-03-01

Structural characterization of a Type B chloramphenicol acetyltransferase from the emerging pathogen Elizabethkingia anophelis NUHP1

by Seyed Mohammad Ghafoori, Alyssa M. Robles, Angelika M. Arada, Paniz Shirmast, David M. Dranow, Stephen J. Mayclin, Donald D. Lorimer, Peter J. Myler, Thomas E. Edwards, Misty L. Kuhn, Jade K. Forwood
Published 2021-05-01

Structure of a Burkholderia pseudomallei trimeric autotransporter adhesin head.

by Thomas E Edwards, Isabelle Phan, Jan Abendroth, Shellie H Dieterich, Amir Masoudi, Wenjin Guo, Stephen N Hewitt, Angela Kelley, David Leibly, Mitch J Brittnacher, Bart L Staker, Samuel I Miller, Wesley C Van Voorhis, Peter J Myler, Lance J Stewart
Published 2010-09-01

Metabolic reprogramming during purine stress in the protozoan pathogen Leishmania donovani.

by Jessica L Martin, Phillip A Yates, Radika Soysa, Joshua F Alfaro, Feng Yang, Kristin E Burnum-Johnson, Vladislav A Petyuk, Karl K Weitz, David G Camp, Richard D Smith, Phillip A Wilmarth, Larry L David, Gowthaman Ramasamy, Peter J Myler, Nicola S Carter
Published 2014-02-01

In silico detection of SARS-CoV-2 specific B-cell epitopes and validation in ELISA for serological diagnosis of COVID-19

by Isabelle Q. Phan, Sandhya Subramanian, David Kim, Michael Murphy, Deleah Pettie, Lauren Carter, Ivan Anishchenko, Lynn K. Barrett, Justin Craig, Logan Tillery, Roger Shek, Whitney E. Harrington, David M. Koelle, Anna Wald, David Veesler, Neil King, Jim Boonyaratanakornkit, Nina Isoherranen, Alexander L. Greninger, Keith R. Jerome, Helen Chu, Bart Staker, Lance Stewart, Peter J. Myler, Wesley C. Van Voorhis
Published 2021-02-01

Biological and structural characterization of a host-adapting amino acid in influenza virus.

by Shinya Yamada, Masato Hatta, Bart L Staker, Shinji Watanabe, Masaki Imai, Kyoko Shinya, Yuko Sakai-Tagawa, Mutsumi Ito, Makoto Ozawa, Tokiko Watanabe, Saori Sakabe, Chengjun Li, Jin Hyun Kim, Peter J Myler, Isabelle Phan, Amy Raymond, Eric Smith, Robin Stacy, Chairul A Nidom, Simon M Lank, Roger W Wiseman, Benjamin N Bimber, David H O'Connor, Gabriele Neumann, Lance J Stewart, Yoshihiro Kawaoka
Published 2010-08-01

Combining functional and structural genomics to sample the essential Burkholderia structome.

by Loren Baugh, Larry A Gallagher, Rapatbhorn Patrapuvich, Matthew C Clifton, Anna S Gardberg, Thomas E Edwards, Brianna Armour, Darren W Begley, Shellie H Dieterich, David M Dranow, Jan Abendroth, James W Fairman, David Fox, Bart L Staker, Isabelle Phan, Angela Gillespie, Ryan Choi, Steve Nakazawa-Hewitt, Mary Trang Nguyen, Alberto Napuli, Lynn Barrett, Garry W Buchko, Robin Stacy, Peter J Myler, Lance J Stewart, Colin Manoil, Wesley C Van Voorhis
Published 2013-01-01

Naegleria fowleri: Protein structures to facilitate drug discovery for the deadly, pathogenic free-living amoeba.

by Logan Tillery, Kayleigh Barrett, Jenna Goldstein, Jared W Lassner, Bram Osterhout, Nathan L Tran, Lily Xu, Ryan M Young, Justin Craig, Ian Chun, David M Dranow, Jan Abendroth, Silvia L Delker, Douglas R Davies, Stephen J Mayclin, Brandy Calhoun, Madison J Bolejack, Bart Staker, Sandhya Subramanian, Isabelle Phan, Donald D Lorimer, Peter J Myler, Thomas E Edwards, Dennis E Kyle, Christopher A Rice, James C Morris, James W Leahy, Roman Manetsch, Lynn K Barrett, Craig L Smith, Wesley C Van Voorhis
Published 2021-01-01