Therapeutic potential of nuclear receptor agonists in Alzheimer's disease

by Miguel Moutinho, Gary E. Landreth
Published 2017-10-01

Inflammation, microglia, and alzheimer's disease

by Brent Cameron, Gary E. Landreth
Published 2010-03-01

Nuclear receptor agonist-driven modification of inflammation and amyloid pathology enhances and sustains cognitive improvements in a mouse model of Alzheimer’s disease

by Brad T. Casali, Erin G. Reed-Geaghan, Gary E. Landreth
Published 2018-02-01

TREM2 in Neurodegenerative Diseases

by Taylor R. Jay, Victoria E. von Saucken, Gary E. Landreth
Published 2017-08-01

The effect of amyloid on microglia-neuron interactions before plaque onset occurs independently of TREM2 in a mouse model of Alzheimer's disease

by Victoria E. von Saucken, Taylor R. Jay, Gary E. Landreth
Published 2020-11-01

Microglia depletion rapidly and reversibly alters amyloid pathology by modification of plaque compaction and morphologies

by Brad T. Casali, Kathryn P. MacPherson, Erin G. Reed-Geaghan, Gary E. Landreth
Published 2020-08-01

ERK Signaling Is Essential for Macrophage Development.

by Edward T Richardson, Supriya Shukla, Nancy Nagy, W Henry Boom, Rose C Beck, Lan Zhou, Gary E Landreth, Clifford V Harding
Published 2015-01-01

Erk1 and Erk2 regulate endothelial cell proliferation and migration during mouse embryonic angiogenesis.

by Ruchika Srinivasan, Tahera Zabuawala, Hong Huang, Jianying Zhang, Parul Gulati, Soledad Fernandez, J Colleen Karlo, Gary E Landreth, Gustavo Leone, Michael C Ostrowski
Published 2009-12-01

INPP5D expression is associated with risk for Alzheimer's disease and induced by plaque-associated microglia

by Andy P. Tsai, Peter Bor-Chian Lin, Chuanpeng Dong, Miguel Moutinho, Brad T. Casali, Yunlong Liu, Bruce T. Lamb, Gary E. Landreth, Adrian L. Oblak, Kwangsik Nho
Published 2021-06-01

TREM2 deficiency exacerbates tau pathology through dysregulated kinase signaling in a mouse model of tauopathy

by Shane M. Bemiller, Tyler J. McCray, Kevin Allan, Shane V. Formica, Guixiang Xu, Gina Wilson, Olga N. Kokiko-Cochran, Samuel D. Crish, Cristian A. Lasagna-Reeves, Richard M. Ransohoff, Gary E. Landreth, Bruce T. Lamb
Published 2017-10-01

Trem2 Y38C mutation and loss of Trem2 impairs neuronal synapses in adult mice

by Vaishnavi S. Jadhav, Peter B. C. Lin, Taylor Pennington, Gonzalo Viana Di Prisco, Asha Jacob Jannu, Guixiang Xu, Miguel Moutinho, Jie Zhang, Brady K. Atwood, Shweta S. Puntambekar, Stephanie J. Bissel, Adrian L. Oblak, Gary E. Landreth, Bruce T. Lamb
Published 2020-10-01

The Trem2 R47H variant confers loss-of-function-like phenotypes in Alzheimer’s disease

by Paul J. Cheng-Hathaway, Erin G. Reed-Geaghan, Taylor R. Jay, Brad T. Casali, Shane M. Bemiller, Shweta S. Puntambekar, Victoria E. von Saucken, Roxanne Y. Williams, J. Colleen Karlo, Miguel Moutinho, Guixiang Xu, Richard M. Ransohoff, Bruce T. Lamb, Gary E. Landreth
Published 2018-06-01