Metabolic Defects Caused by High-Fat Diet Modify Disease Risk through Inflammatory and Amyloidogenic Pathways in a Mouse Model of Alzheimer’s Disease

by Austin M. Reilly, Andy P. Tsai, Peter B. Lin, Aaron C. Ericsson, Adrian L. Oblak, Hongxia Ren
Published 2020-09-01

INPP5D expression is associated with risk for Alzheimer's disease and induced by plaque-associated microglia

by Andy P. Tsai, Peter Bor-Chian Lin, Chuanpeng Dong, Miguel Moutinho, Brad T. Casali, Yunlong Liu, Bruce T. Lamb, Gary E. Landreth, Adrian L. Oblak, Kwangsik Nho
Published 2021-06-01

Tau as a mediator of neurotoxicity associated to cerebral amyloid angiopathy

by Yingjian You, Abigail Perkins, Pablo Cisternas, Braulio Muñoz, Xavier Taylor, Yanwen You, Holly J. Garringer, Adrian L. Oblak, Brady K. Atwood, Ruben Vidal, Cristian A. Lasagna-Reeves
Published 2019-02-01

Moderate Ethanol Pre-treatment Mitigates ICH-Induced Injury via ER Stress Modulation in Rats

by Peter Bor-Chian Lin, Po-Kai Wang, Po-Kai Wang, Cheng-Yoong Pang, Cheng-Yoong Pang, Wei-Fen Hu, Andy Po-Yi Tsai, Adrian L. Oblak, Hock-Kean Liew, Hock-Kean Liew, Hock-Kean Liew
Published 2021-06-01

Comprehensive Evaluation of the 5XFAD Mouse Model for Preclinical Testing Applications: A MODEL-AD Study

by Adrian L. Oblak, Adrian L. Oblak, Peter B. Lin, Kevin P. Kotredes, Ravi S. Pandey, Dylan Garceau, Harriet M. Williams, Asli Uyar, Rita O’Rourke, Sarah O’Rourke, Cynthia Ingraham, Daria Bednarczyk, Melisa Belanger, Zackary A. Cope, Gabriela J. Little, Sean-Paul G. Williams, Carl Ash, Adam Bleckert, Tim Ragan, Benjamin A. Logsdon, Lara M. Mangravite, Stacey J. Sukoff Rizzo, Paul R. Territo, Paul R. Territo, Gregory W. Carter, Gareth R. Howell, Michael Sasner, Bruce T. Lamb, Bruce T. Lamb
Published 2021-07-01

Trem2 Y38C mutation and loss of Trem2 impairs neuronal synapses in adult mice

by Vaishnavi S. Jadhav, Peter B. C. Lin, Taylor Pennington, Gonzalo Viana Di Prisco, Asha Jacob Jannu, Guixiang Xu, Miguel Moutinho, Jie Zhang, Brady K. Atwood, Shweta S. Puntambekar, Stephanie J. Bissel, Adrian L. Oblak, Gary E. Landreth, Bruce T. Lamb
Published 2020-10-01

A novel systems biology approach to evaluate mouse models of late-onset Alzheimer’s disease

by Christoph Preuss, Ravi Pandey, Erin Piazza, Alexander Fine, Asli Uyar, Thanneer Perumal, Dylan Garceau, Kevin P. Kotredes, Harriet Williams, Lara M. Mangravite, Bruce T. Lamb, Adrian L. Oblak, Gareth R. Howell, Michael Sasner, Benjamin A. Logsdon, the MODEL-AD Consortium, Gregory W. Carter
Published 2020-11-01

Distinct Neurodegenerative Changes in an Induced Pluripotent Stem Cell Model of Frontotemporal Dementia Linked to Mutant TAU Protein

by Marc Ehrlich, Anna-Lena Hallmann, Peter Reinhardt, Marcos J. Araúzo-Bravo, Sabrina Korr, Albrecht Röpke, Olympia E. Psathaki, Petra Ehling, Sven G. Meuth, Adrian L. Oblak, Jill R. Murrell, Bernardino Ghetti, Holm Zaehres, Hans R. Schöler, Jared Sterneckert, Tanja Kuhlmann, Gunnar Hargus
Published 2015-07-01