Quercetin potentializes the respective cytotoxic activity of gemcitabine or doxorubicin on 3D culture of AsPC-1 or HepG2 cells, through the inhibition of HIF-1α and MDR1.

by Sarah Hassan, Jean Peluso, Sandra Chalhoub, Ysia Idoux Gillet, Nadia Benkirane-Jessel, Natacha Rochel, Guy Fuhrmann, Genevieve Ubeaud-Sequier
Published 2020-01-01

Flavagline synthetic derivative induces senescence in glioblastoma cancer cells without being toxic to healthy astrocytes

by Ezeddine Harmouch, Joseph Seitlinger, Hassan Chaddad, Geneviève Ubeaud-Sequier, Jochen Barths, Sani Saidu, Laurent Désaubry, Stéphanie Grandemange, Thierry Massfelder, Guy Fuhrmann, Florence Fioretti, Monique Dontenwill, Nadia Benkirane-Jessel, Ysia Idoux-Gillet
Published 2020-08-01