Highly selective inhibition of Bruton’s tyrosine kinase attenuates skin and brain disease in murine lupus

by Samantha A. Chalmers, Jing Wen, Jessica Doerner, Ariel Stock, Carla M. Cuda, Hadijat M. Makinde, Harris Perlman, Todd Bosanac, Deborah Webb, Gerald Nabozny, Jay S. Fine, Elliott Klein, Meera Ramanujam, Chaim Putterman
Published 2018-01-01

Paradoxical Augmentation of Experimental Spondyloarthritis by RORC Inhibition in HLA-B27 Transgenic Rats

by Melissa N. van Tok, Melissa N. van Tok, Mohamed Mandour, Mohamed Mandour, Joseph Wahle, Mark E. Labadia, Marleen G. H. van de Sande, Marleen G. H. van de Sande, Gerald Nabozny, Dominique L. Baeten, Dominique L. Baeten, Leonie M. van Duivenvoorde, Leonie M. van Duivenvoorde
Published 2021-09-01

An RORγt Oral Inhibitor Modulates IL-17 Responses in Peripheral Blood and Intestinal Mucosa of Crohn's Disease Patients

by Helena Bassolas-Molina, Ernest Raymond, Mark Labadia, Joseph Wahle, Elena Ferrer-Picón, Mark Panzenbeck, Jie Zheng, Christian Harcken, Robert Hughes, Michael Turner, Dustin Smith, Elisabeth Calderón-Gómez, Míriam Esteller, Anna Carrasco, Anna Carrasco, Maria Esteve, Maria Esteve, Isabella Dotti, Ana Maria Corraliza, Maria Carme Masamunt, Clàudia Arajol, Jordi Guardiola, Elena Ricart, Gerald Nabozny, Azucena Salas
Published 2018-10-01

RORγt inhibition selectively targets IL-17 producing iNKT and γδ-T cells enriched in Spondyloarthritis patients

by Koen Venken, Peggy Jacques, Céline Mortier, Mark E. Labadia, Tine Decruy, Julie Coudenys, Kathleen Hoyt, Anita L. Wayne, Robert Hughes, Michael Turner, Sofie Van Gassen, Liesbet Martens, Dustin Smith, Christian Harcken, Joseph Wahle, Chao-Ting Wang, Eveline Verheugen, Nadia Schryvers, Gaëlle Varkas, Heleen Cypers, Ruth Wittoek, Yves Piette, Lieve Gyselbrecht, Serge Van Calenbergh, Filip Van den Bosch, Yvan Saeys, Gerald Nabozny, Dirk Elewaut
Published 2019-01-01

Kcnn4 Is a Regulator of Macrophage Multinucleation in Bone Homeostasis and Inflammatory Disease

by Heeseog Kang, Audrey Kerloc’h, Maxime Rotival, Xiaoqing Xu, Qing Zhang, Zelpha D’Souza, Michael Kim, Jodi Carlson Scholz, Jeong-Hun Ko, Prashant K. Srivastava, Jonathan R. Genzen, Weiguo Cui, Timothy J. Aitman, Laurence Game, James E. Melvin, Adedayo Hanidu, Janice Dimock, Jie Zheng, Donald Souza, Aruna K. Behera, Gerald Nabozny, H. Terence Cook, J.H. Duncan Bassett, Graham R. Williams, Jun Li, Agnès Vignery, Enrico Petretto, Jacques Behmoaras
Published 2014-08-01