Parkinson's disease-associated genetic variation is linked to quantitative expression of inflammatory genes.

by Steven Pierce, Gerhard A Coetzee
Published 2017-01-01

Functions of Intracellular Alpha-Synuclein in Microglia: Implications for Parkinson’s Disease Risk

by Alix Booms, Gerhard A. Coetzee
Published 2021-10-01

Parkinson's disease genetic risk in a midbrain neuronal cell line

by Steven E. Pierce, Trevor Tyson, Alix Booms, Jordan Prahl, Gerhard A. Coetzee
Published 2018-06-01

CRISPR-mediated deletion of prostate cancer risk-associated CTCF loop anchors identifies repressive chromatin loops

by Yu Guo, Andrew A. Perez, Dennis J. Hazelett, Gerhard A. Coetzee, Suhn Kyong Rhie, Peggy J. Farnham
Published 2018-10-01

Comprehensive functional annotation of seventy-one breast cancer risk Loci.

by Suhn Kyong Rhie, Simon G Coetzee, Houtan Noushmehr, Chunli Yan, Jae Mun Kim, Christopher A Haiman, Gerhard A Coetzee
Published 2013-01-01

An enhancer from the 8q24 prostate cancer risk region is sufficient to direct reporter gene expression to a subset of prostate stem-like epithelial cells in transgenic mice

by Man-Chun Ting, Chun-Peng Liao, Chunli Yan, Li Jia, Susan Groshen, Baruch Frenkel, Pradip Roy-Burman, Gerhard A. Coetzee, Robert Maxson
Published 2012-05-01

Genomic androgen receptor-occupied regions with different functions, defined by histone acetylation, coregulators and transcriptional capacity.

by Li Jia, Benjamin P Berman, Unnati Jariwala, Xiting Yan, Jon P Cogan, Allison Walters, Ting Chen, Grant Buchanan, Baruch Frenkel, Gerhard A Coetzee
Published 2008-01-01

TPL2/COT/MAP3K8 (TPL2) activation promotes androgen depletion-independent (ADI) prostate cancer growth.

by Joseph H Jeong, Ayesha Bhatia, Zsolt Toth, Soohwan Oh, Kyung-Soo Inn, Chun-Peng Liao, Pradip Roy-Burman, Jonathan Melamed, Gerhard A Coetzee, Jae U Jung
Published 2011-01-01

Expression and functional role of orphan receptor GPR158 in prostate cancer growth and progression.

by Nitin Patel, Tatsuo Itakura, Shinwu Jeong, Chun-Peng Liao, Pradip Roy-Burman, Ebrahim Zandi, Susan Groshen, Jacek Pinski, Gerhard A Coetzee, Mitchell E Gross, M Elizabeth Fini
Published 2015-01-01

A 3-basepair deletion in repeat 1 of the LDL receptor promoter reduces transcriptional activity in a South African Pedi

by Armand V. Peeters, Maritha J. Kotze, Charlotte L. Scholtz, Linda F. De Waal, David C. Rubinsztein, Gerhard A. Coetzee, Giovanni Zuliani, Raphael Streiff, Jingwen Liu, Deneys R. van der Westhuyzen
Published 1998-05-01

Functional enhancers at the gene-poor 8q24 cancer-linked locus.

by Li Jia, Gilad Landan, Mark Pomerantz, Rami Jaschek, Paula Herman, David Reich, Chunli Yan, Omar Khalid, Phil Kantoff, William Oh, J Robert Manak, Benjamin P Berman, Brian E Henderson, Baruch Frenkel, Christopher A Haiman, Matthew Freedman, Amos Tanay, Gerhard A Coetzee
Published 2009-08-01

Comprehensive functional annotation of 77 prostate cancer risk loci.

by Dennis J Hazelett, Suhn Kyong Rhie, Malaina Gaddis, Chunli Yan, Daniel L Lakeland, Simon G Coetzee, Ellipse/GAME-ON consortium, Practical consortium, Brian E Henderson, Houtan Noushmehr, Wendy Cozen, Zsofia Kote-Jarai, Rosalind A Eeles, Douglas F Easton, Christopher A Haiman, Wange Lu, Peggy J Farnham, Gerhard A Coetzee
Published 2014-01-01