Regulatory Considerations for the Mother, Fetus and Neonate in Fetal Pharmacology Modeling

by Dionna J. Green, Kyunghun Park, Varsha Bhatt-Mehta, Donna Snyder, Gilbert J. Burckart
Published 2021-07-01

Assessing CYP2C19 Ontogeny in Neonates and Infants Using Physiologically Based Pharmacokinetic Models: Impact of Enzyme Maturation Versus Inhibition

by Peng Duan, Fang Wu, Jason N. Moore, Jeffrey Fisher, Victor Crentsil, Daniel Gonzalez, Lei Zhang, Gilbert J. Burckart, Jian Wang
Published 2019-03-01

Approaches to Dose Finding in Neonates, Illustrating the Variability between Neonatal Drug Development Programs

by John N. Van den Anker, Susan McCune, Pieter Annaert, Gerri R. Baer, Yeruk Mulugeta, Ramy Abdelrahman, Kunyi Wu, Kevin M. Krudys, Jeffrey Fisher, William Slikker, Connie Chen, Gilbert J. Burckart, Karel Allegaert
Published 2020-07-01