Maintenance of redox homeostasis by hypoxia-inducible factors

by Debangshu Samanta, Gregg L. Semenza
Published 2017-10-01

BIRC2 Expression Impairs Anti-Cancer Immunity and Immunotherapy Efficacy

by Debangshu Samanta, Tina Yi-Ting Huang, Rima Shah, Yongkang Yang, Fan Pan, Gregg L. Semenza
Published 2020-08-01

HIF-1α activation by intermittent hypoxia requires NADPH oxidase stimulation by xanthine oxidase.

by Jayasri Nanduri, Damodara Reddy Vaddi, Shakil A Khan, Ning Wang, Vladislav Makarenko, Gregg L Semenza, Nanduri R Prabhakar
Published 2015-01-01

Chemotherapy-Induced Ca2+ Release Stimulates Breast Cancer Stem Cell Enrichment

by Haiquan Lu, Ivan Chen, Larissa A. Shimoda, Youngrok Park, Chuanzhao Zhang, Linh Tran, Huimin Zhang, Gregg L. Semenza
Published 2017-02-01

Macrophage migration inhibitory factor activates hypoxia-inducible factor in a p53-dependent manner.

by Seiko Oda, Tomoyuki Oda, Kenichiro Nishi, Satoshi Takabuchi, Takuhiko Wakamatsu, Tomoharu Tanaka, Takehiko Adachi, Kazuhiko Fukuda, Gregg L Semenza, Kiichi Hirota
Published 2008-01-01

HIF-1 recruits NANOG as a coactivator for TERT gene transcription in hypoxic breast cancer stem cells

by Haiquan Lu, Yajing Lyu, Linh Tran, Jie Lan, Yangyiran Xie, Yongkang Yang, Naveena L. Murugan, Yueyang J. Wang, Gregg L. Semenza
Published 2021-09-01

Hypoxia regulates CD44 and its variant isoforms through HIF-1α in triple negative breast cancer.

by Balaji Krishnamachary, Marie-France Penet, Sridhar Nimmagadda, Yelena Mironchik, Venu Raman, Meiyappan Solaiyappan, Gregg L Semenza, Martin G Pomper, Zaver M Bhujwalla
Published 2012-01-01

Expression of the angiogenic mediator, angiopoietin-like 4, in the eyes of patients with proliferative sickle retinopathy.

by Kathleen Jee, Murilo Rodrigues, Fabiana Kashiwabuchi, Brooks P Applewhite, Ian Han, Gerard Lutty, Morton F Goldberg, Gregg L Semenza, Silvia Montaner, Akrit Sodhi
Published 2017-01-01

HIF-1-Mediated Suppression of Acyl-CoA Dehydrogenases and Fatty Acid Oxidation Is Critical for Cancer Progression

by De Huang, Tingting Li, Xinghua Li, Long Zhang, Linchong Sun, Xiaoping He, Xiuying Zhong, Dongya Jia, Libing Song, Gregg L. Semenza, Ping Gao, Huafeng Zhang
Published 2014-09-01

A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension

by Swati Dabral, Christian Muecke, Chanil Valasarajan, Mario Schmoranzer, Astrid Wietelmann, Gregg L. Semenza, Michael Meister, Thomas Muley, Tamina Seeger-Nukpezah, Christos Samakovlis, Norbert Weissmann, Friedrich Grimminger, Werner Seeger, Rajkumar Savai, Soni S. Pullamsetti
Published 2019-05-01