Iron accumulation in tumor-associated macrophages marks an improved overall survival in patients with lung adenocarcinoma

by Carl Maximilian Thielmann, Milene Costa da Silva, Thomas Muley, Michael Meister, Esther Herpel, Martina U. Muckenthaler
Published 2019-08-01

Low Input Whole-Exome Sequencing to Determine the Representation of the Tumor Exome in Circulating DNA of Non-Small Cell Lung Cancer Patients.

by Steffen Dietz, Uwe Schirmer, Clémentine Mercé, Nikolas von Bubnoff, Edgar Dahl, Michael Meister, Thomas Muley, Michael Thomas, Holger Sültmann
Published 2016-01-01

FAM83A and FAM83B as Prognostic Biomarkers and Potential New Therapeutic Targets in NSCLC

by Sarah Richtmann, Dennis Wilkens, Arne Warth, Felix Lasitschka, Hauke Winter, Petros Christopoulos, Felix J. F. Herth, Thomas Muley, Michael Meister, Marc A. Schneider
Published 2019-05-01

Molecular signatures in IASLC/ATS/ERS classified growth patterns of lung adenocarcinoma.

by Heike Zabeck, Hendrik Dienemann, Hans Hoffmann, Joachim Pfannschmidt, Arne Warth, Philipp A Schnabel, Thomas Muley, Michael Meister, Holger Sültmann, Holger Fröhlich, Ruprecht Kuner, Felix Lasitschka
Published 2018-01-01

Glycodelin as a Serum and Tissue Biomarker for Metastatic and Advanced NSCLC

by Marc A. Schneider, Thomas Muley, Rebecca Weber, Sabine Wessels, Michael Thomas, Felix J. F. Herth, Nicolas C. Kahn, Ralf Eberhardt, Hauke Winter, Gudula Heussel, Arne Warth, Christel Herold-Mende, Michael Meister
Published 2018-12-01

A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension

by Swati Dabral, Christian Muecke, Chanil Valasarajan, Mario Schmoranzer, Astrid Wietelmann, Gregg L. Semenza, Michael Meister, Thomas Muley, Tamina Seeger-Nukpezah, Christos Samakovlis, Norbert Weissmann, Friedrich Grimminger, Werner Seeger, Rajkumar Savai, Soni S. Pullamsetti
Published 2019-05-01

Fibroblast Growth Factor—14 Acts as Tumor Suppressor in Lung Adenocarcinomas

by Kati Turkowski, Frederik Herzberg, Stefan Günther, David Brunn, Andreas Weigert, Michael Meister, Thomas Muley, Mark Kriegsmann, Marc A. Schneider, Hauke Winter, Michael Thomas, Friedrich Grimminger, Werner Seeger, Soni Savai Pullamsetti, Rajkumar Savai
Published 2020-07-01

Novel Chimeric Gene Therapy Vectors Based on Adeno-Associated Virus and Four Different Mammalian Bocaviruses

by Julia Fakhiri, Marc A. Schneider, Jens Puschhof, Megan Stanifer, Verena Schildgen, Stefan Holderbach, Yannik Voss, Jihad El Andari, Oliver Schildgen, Steeve Boulant, Michael Meister, Hans Clevers, Ziying Yan, Jianming Qiu, Dirk Grimm
Published 2019-03-01

Iron Induces Anti-tumor Activity in Tumor-Associated Macrophages

by Milene Costa da Silva, Milene Costa da Silva, Milene Costa da Silva, Milene Costa da Silva, Milene Costa da Silva, Michael O. Breckwoldt, Michael O. Breckwoldt, Francesca Vinchi, Francesca Vinchi, Margareta P. Correia, Ana Stojanovic, Carl Maximilian Thielmann, Carl Maximilian Thielmann, Michael Meister, Michael Meister, Thomas Muley, Thomas Muley, Arne Warth, Arne Warth, Michael Platten, Michael Platten, Matthias W. Hentze, Adelheid Cerwenka, Adelheid Cerwenka, Martina U. Muckenthaler, Martina U. Muckenthaler, Martina U. Muckenthaler
Published 2017-11-01

Germline Genetic Variants of the Renin-Angiotensin System, Hypoxia and Angiogenesis in Non-Small Cell Lung Cancer Progression: Discovery and Validation Studies

by Maria Joana Catarata, Rui Medeiros, Maria José Oliveira, Alice Pêgo, João Gonçalo Frade, Maria Fátima Martins, Carlos Robalo Cordeiro, Felix J F Herth, Michael Thomas, Mark Kriegsmann, Michael Meister, Marc A Schneider, Thomas Muley, Ricardo Ribeiro
Published 2020-12-01

Novel Liquid Biomarker Panels for A Very Early Response Capturing of NSCLC Therapies in Advanced Stages

by Florian Janke, Farastuk Bozorgmehr, Sabine Wrenger, Steffen Dietz, Claus P. Heussel, Gudula Heussel, Carlos F. Silva, Stephan Rheinheimer, Manuel Feisst, Michael Thomas, Heiko Golpon, Andreas Günther, Holger Sültmann, Thomas Muley, Sabina Janciauskiene, Michael Meister, Marc A. Schneider
Published 2020-04-01

CT characteristics in pulmonary adenocarcinoma with epidermal growth factor receptor mutation.

by Jing Zhao, Julien Dinkel, Arne Warth, Roland Penzel, Niels Reinmuth, Philipp Schnabel, Thomas Muley, Michael Meister, Heike Zabeck, Martin Steins, Jian-Yong Yang, Qian Zhou, Heinz-Peter Schlemmer, Felix J F Herth, Hans-Ulrich Kauczor, Claus Peter Heussel
Published 2017-01-01

A gene expression signature associated with B cells predicts benefit from immune checkpoint blockade in lung adenocarcinoma

by Jan Budczies, Martina Kirchner, Klaus Kluck, Daniel Kazdal, Julia Glade, Michael Allgäuer, Mark Kriegsmann, Claus-Peter Heußel, Felix J. Herth, Hauke Winter, Michael Meister, Thomas Muley, Stefan Fröhling, Solange Peters, Barbara Seliger, Peter Schirmacher, Michael Thomas, Petros Christopoulos, Albrecht Stenzinger
Published 2021-01-01

Clinical Significance of <i>SERPINA1</i> Gene and Its Encoded Alpha1-antitrypsin Protein in NSCLC

by Evrim Ercetin, Sarah Richtmann, Beatriz Martinez Delgado, Gema Gomez-Mariano, Sabine Wrenger, Elena Korenbaum, Bin Liu, David DeLuca, Mark P. Kühnel, Danny Jonigk, Kadriya Yuskaeva, Arne Warth, Thomas Muley, Hauke Winter, Michael Meister, Tobias Welte, Sabina Janciauskiene, Marc A. Schneider
Published 2019-09-01

Detection of TP53 Mutations in Tissue or Liquid Rebiopsies at Progression Identifies ALK+ Lung Cancer Patients with Poor Survival

by Petros Christopoulos, Steffen Dietz, Martina Kirchner, Anna-Lena Volckmar, Volker Endris, Olaf Neumann, Simon Ogrodnik, Claus-Peter Heussel, Felix J. Herth, Martin Eichhorn, Michael Meister, Jan Budczies, Michael Allgäuer, Jonas Leichsenring, Tomasz Zemojtel, Helge Bischoff, Peter Schirmacher, Michael Thomas, Holger Sültmann, Albrecht Stenzinger
Published 2019-01-01

Real-world implementation of sequential targeted therapies for EGFR-mutated lung cancer

by Nikolaus Magios, Farastuk Bozorgmehr, Anna-Lena Volckmar, Daniel Kazdal, Martina Kirchner, Felix J. Herth, Claus-Peter Heussel, Florian Eichhorn, Michael Meister, Thomas Muley, Rami A. Elshafie, Jürgen R. Fischer, Martin Faehling, Mark Kriegsmann, Peter Schirmacher, Helge Bischoff, Albrecht Stenzinger, Michael Thomas, Petros Christopoulos
Published 2021-03-01

Longitudinal therapy monitoring of ALK-positive lung cancer by combined copy number and targeted mutation profiling of cell-free DNA

by Steffen Dietz, Petros Christopoulos, Zhao Yuan, Arlou Kristina Angeles, Lisa Gu, Anna-Lena Volckmar, Simon J. Ogrodnik, Florian Janke, Chiara Dalle Fratte, Tomasz Zemojtel, Marc A. Schneider, Daniel Kazdal, Volker Endris, Michael Meister, Thomas Muley, Erika Cecchin, Martin Reck, Matthias Schlesner, Michael Thomas, Albrecht Stenzinger, Holger Sültmann
Published 2020-12-01

Informed conditioning on clinical covariates increases power in case-control association studies.

by Noah Zaitlen, Sara Lindström, Bogdan Pasaniuc, Marilyn Cornelis, Giulio Genovese, Samuela Pollack, Anne Barton, Heike Bickeböller, Donald W Bowden, Steve Eyre, Barry I Freedman, David J Friedman, John K Field, Leif Groop, Aage Haugen, Joachim Heinrich, Brian E Henderson, Pamela J Hicks, Lynne J Hocking, Laurence N Kolonel, Maria Teresa Landi, Carl D Langefeld, Loic Le Marchand, Michael Meister, Ann W Morgan, Olaide Y Raji, Angela Risch, Albert Rosenberger, David Scherf, Sophia Steer, Martin Walshaw, Kevin M Waters, Anthony G Wilson, Paul Wordsworth, Shanbeh Zienolddiny, Eric Tchetgen Tchetgen, Christopher Haiman, David J Hunter, Robert M Plenge, Jane Worthington, David C Christiani, Debra A Schaumberg, Daniel I Chasman, David Altshuler, Benjamin Voight, Peter Kraft, Nick Patterson, Alkes L Price
Published 2012-01-01