Reverse GWAS: Using genetics to identify and model phenotypic subtypes.

by Andy Dahl, Na Cai, Arthur Ko, Markku Laakso, Päivi Pajukanta, Jonathan Flint, Noah Zaitlen
Published 2019-04-01

Tracing cellular heterogeneity in pooled genetic screens via multi-level barcoding

by Michael Boettcher, Sergio Covarrubias, Anne Biton, James Blau, Haopeng Wang, Noah Zaitlen, Michael T. McManus
Published 2019-02-01

Using extended genealogy to estimate components of heritability for 23 quantitative and dichotomous traits.

by Noah Zaitlen, Peter Kraft, Nick Patterson, Bogdan Pasaniuc, Gaurav Bhatia, Samuela Pollack, Alkes L Price
Published 2013-05-01

GBAT: a gene-based association test for robust detection of trans-gene regulation

by Xuanyao Liu, Joel A. Mefford, Andrew Dahl, Yuan He, Meena Subramaniam, Alexis Battle, Alkes L. Price, Noah Zaitlen
Published 2020-08-01

Comprehensive cell type decomposition of circulating cell-free DNA with CelFiE

by Christa Caggiano, Barbara Celona, Fleur Garton, Joel Mefford, Brian L. Black, Robert Henderson, Catherine Lomen-Hoerth, Andrew Dahl, Noah Zaitlen
Published 2021-05-01

Modeling epistasis in mice and yeast using the proportion of two or more distinct genetic backgrounds: Evidence for "polygenic epistasis".

by Christoph D Rau, Natalia M Gonzales, Joshua S Bloom, Danny Park, Julien Ayroles, Abraham A Palmer, Aldons J Lusis, Noah Zaitlen
Published 2020-10-01

A comprehensive study of metabolite genetics reveals strong pleiotropy and heterogeneity across time and context

by Apolline Gallois, Joel Mefford, Arthur Ko, Amaury Vaysse, Hanna Julienne, Mika Ala-Korpela, Markku Laakso, Noah Zaitlen, Päivi Pajukanta, Hugues Aschard
Published 2019-10-01

Genetic and environmental perturbations lead to regulatory decoherence

by Amanda Lea, Meena Subramaniam, Arthur Ko, Terho Lehtimäki, Emma Raitoharju, Mika Kähönen, Ilkka Seppälä, Nina Mononen, Olli T Raitakari, Mika Ala-Korpela, Päivi Pajukanta, Noah Zaitlen, Julien F Ayroles
Published 2019-03-01

Genetic effects on the commensal microbiota in inflammatory bowel disease patients.

by Hugues Aschard, Vincent Laville, Eric Tchetgen Tchetgen, Dan Knights, Floris Imhann, Philippe Seksik, Noah Zaitlen, Mark S Silverberg, Jacques Cosnes, Rinse K Weersma, Ramnik Xavier, Laurent Beaugerie, David Skurnik, Harry Sokol
Published 2019-03-01

Cis-eQTL-based trans-ethnic meta-analysis reveals novel genes associated with breast cancer risk.

by Joshua D Hoffman, Rebecca E Graff, Nima C Emami, Caroline G Tai, Michael N Passarelli, Donglei Hu, Scott Huntsman, Dexter Hadley, Lancelote Leong, Arunabha Majumdar, Noah Zaitlen, Elad Ziv, John S Witte
Published 2017-03-01

Quantifying missing heritability at known GWAS loci.

by Alexander Gusev, Gaurav Bhatia, Noah Zaitlen, Bjarni J Vilhjalmsson, Dorothée Diogo, Eli A Stahl, Peter K Gregersen, Jane Worthington, Lars Klareskog, Soumya Raychaudhuri, Robert M Plenge, Bogdan Pasaniuc, Alkes L Price
Published 2013-01-01

Correction: Pleiotropic Mechanisms Indicated for Sex Differences in Autism.

by Ileena Mitra, Kathryn Tsang, Christine Ladd-Acosta, Lisa A Croen, Kimberly A Aldinger, Robert L Hendren, Michela Traglia, Alinoë Lavillaureix, Noah Zaitlen, Michael C Oldham, Pat Levitt, Stanley Nelson, David G Amaral, Irva Hertz-Picciotto, M Daniele Fallin, Lauren A Weiss
Published 2017-06-01

Pleiotropic Mechanisms Indicated for Sex Differences in Autism.

by Ileena Mitra, Kathryn Tsang, Christine Ladd-Acosta, Lisa A Croen, Kimberly A Aldinger, Robert L Hendren, Michela Traglia, Alinoë Lavillaureix, Noah Zaitlen, Michael C Oldham, Pat Levitt, Stanley Nelson, David G Amaral, Irva Hertz-Picciotto, M Daniele Fallin, Lauren A Weiss
Published 2016-11-01

Author Correction: Profiling immunoglobulin repertoires across multiple human tissues using RNA sequencing

by Igor Mandric, Jeremy Rotman, Harry Taegyun Yang, Nicolas Strauli, Dennis J. Montoya, William Van Der Wey, Jiem R. Ronas, Benjamin Statz, Douglas Yao, Velislava Petrova, Alex Zelikovsky, Roberto Spreafico, Sagiv Shifman, Noah Zaitlen, Maura Rossetti, K. Mark Ansel, Eleazar Eskin, Serghei Mangul
Published 2020-09-01

Profiling immunoglobulin repertoires across multiple human tissues using RNA sequencing

by Igor Mandric, Jeremy Rotman, Harry Taegyun Yang, Nicolas Strauli, Dennis J. Montoya, William Van Der Wey, Jiem R. Ronas, Benjamin Statz, Douglas Yao, Velislava Petrova, Alex Zelikovsky, Roberto Spreafico, Sagiv Shifman, Noah Zaitlen, Maura Rossetti, K. Mark Ansel, Eleazar Eskin, Serghei Mangul
Published 2020-06-01

On the cross-population generalizability of gene expression prediction models.

by Kevin L Keys, Angel C Y Mak, Marquitta J White, Walter L Eckalbar, Andrew W Dahl, Joel Mefford, Anna V Mikhaylova, María G Contreras, Jennifer R Elhawary, Celeste Eng, Donglei Hu, Scott Huntsman, Sam S Oh, Sandra Salazar, Michael A Lenoir, Jimmie C Ye, Timothy A Thornton, Noah Zaitlen, Esteban G Burchard, Christopher R Gignoux
Published 2020-08-01

Differential methylation between ethnic sub-groups reflects the effect of genetic ancestry and environmental exposures

by Joshua M Galanter, Christopher R Gignoux, Sam S Oh, Dara Torgerson, Maria Pino-Yanes, Neeta Thakur, Celeste Eng, Donglei Hu, Scott Huntsman, Harold J Farber, Pedro C Avila, Emerita Brigino-Buenaventura, Michael A LeNoir, Kelly Meade, Denise Serebrisky, William Rodríguez-Cintrón, Rajesh Kumar, Jose R Rodríguez-Santana, Max A Seibold, Luisa N Borrell, Esteban G Burchard, Noah Zaitlen
Published 2017-01-01

ROP: dumpster diving in RNA-sequencing to find the source of 1 trillion reads across diverse adult human tissues

by Serghei Mangul, Harry Taegyun Yang, Nicolas Strauli, Franziska Gruhl, Hagit T. Porath, Kevin Hsieh, Linus Chen, Timothy Daley, Stephanie Christenson, Agata Wesolowska-Andersen, Roberto Spreafico, Cydney Rios, Celeste Eng, Andrew D. Smith, Ryan D. Hernandez, Roel A. Ophoff, Jose Rodriguez Santana, Erez Y. Levanon, Prescott G. Woodruff, Esteban Burchard, Max A. Seibold, Sagiv Shifman, Eleazar Eskin, Noah Zaitlen
Published 2018-02-01

Informed conditioning on clinical covariates increases power in case-control association studies.

by Noah Zaitlen, Sara Lindström, Bogdan Pasaniuc, Marilyn Cornelis, Giulio Genovese, Samuela Pollack, Anne Barton, Heike Bickeböller, Donald W Bowden, Steve Eyre, Barry I Freedman, David J Friedman, John K Field, Leif Groop, Aage Haugen, Joachim Heinrich, Brian E Henderson, Pamela J Hicks, Lynne J Hocking, Laurence N Kolonel, Maria Teresa Landi, Carl D Langefeld, Loic Le Marchand, Michael Meister, Ann W Morgan, Olaide Y Raji, Angela Risch, Albert Rosenberger, David Scherf, Sophia Steer, Martin Walshaw, Kevin M Waters, Anthony G Wilson, Paul Wordsworth, Shanbeh Zienolddiny, Eric Tchetgen Tchetgen, Christopher Haiman, David J Hunter, Robert M Plenge, Jane Worthington, David C Christiani, Debra A Schaumberg, Daniel I Chasman, David Altshuler, Benjamin Voight, Peter Kraft, Nick Patterson, Alkes L Price
Published 2012-01-01

Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium.

by Bogdan Pasaniuc, Noah Zaitlen, Guillaume Lettre, Gary K Chen, Arti Tandon, W H Linda Kao, Ingo Ruczinski, Myriam Fornage, David S Siscovick, Xiaofeng Zhu, Emma Larkin, Leslie A Lange, L Adrienne Cupples, Qiong Yang, Ermeg L Akylbekova, Solomon K Musani, Jasmin Divers, Joe Mychaleckyj, Mingyao Li, George J Papanicolaou, Robert C Millikan, Christine B Ambrosone, Esther M John, Leslie Bernstein, Wei Zheng, Jennifer J Hu, Regina G Ziegler, Sarah J Nyante, Elisa V Bandera, Sue A Ingles, Michael F Press, Stephen J Chanock, Sandra L Deming, Jorge L Rodriguez-Gil, Cameron D Palmer, Sarah Buxbaum, Lynette Ekunwe, Joel N Hirschhorn, Brian E Henderson, Simon Myers, Christopher A Haiman, David Reich, Nick Patterson, James G Wilson, Alkes L Price
Published 2011-04-01