Structure-Based Design of Nipah Virus Vaccines: A Generalizable Approach to Paramyxovirus Immunogen Development

by Rebecca J. Loomis, Guillaume B. E. Stewart-Jones, Yaroslav Tsybovsky, Ria T. Caringal, Kaitlyn M. Morabito, Jason S. McLellan, Amy L. Chamberlain, Sean T. Nugent, Geoffrey B. Hutchinson, Lisa A. Kueltzo, John R. Mascola, Barney S. Graham
Published 2020-06-01

Comparison of neutralizing antibody responses elicited from highly diverse polyvalent heterotrimeric HIV-1 gp140 cocktail immunogens versus a monovalent counterpart in rhesus macaq...

by Emma J Bowles, Torben Schiffner, Maximillian Rosario, Gemma A Needham, Meghna Ramaswamy, Joanna McGouran, Benedikt Kessler, Celia LaBranche, Andrew J McMichael, David Montefiori, Quentin J Sattentau, Tomáš Hanke, Guillaume B E Stewart-Jones
Published 2014-01-01

Generation of neutralizing antibodies and divergence of SIVmac239 in cynomolgus macaques following short-term early antiretroviral therapy.

by Gülşen Ozkaya Sahin, Emma J Bowles, Joe Parker, Hannes Uchtenhagen, Enas Sheik-Khalil, Stephen Taylor, Oliver G Pybus, Barbro Mäkitalo, Lilian Walther-Jallow, Mats Spångberg, Rigmor Thorstensson, Adnane Achour, Eva Maria Fenyö, Guillaume B E Stewart-Jones, Anna-Lena Spetz
Published 2010-09-01

Protection of calves by a prefusion-stabilized bovine RSV F vaccine

by Baoshan Zhang, Lei Chen, Chiara Silacci, Michelle Thom, Jeffrey C. Boyington, Aliaksandr Druz, M. Gordon Joyce, Efrain Guzman, Wing- Pui Kong, Yen-Ting Lai, Guillaume B. E. Stewart-Jones, Yaroslav Tsybovsky, Yongping Yang, Tongqing Zhou, Ulrich Baxa, John R. Mascola, Davide Corti, Antonio Lanzavecchia, Geraldine Taylor, Peter D. Kwong
Published 2017-03-01

Structure-Based Design of Head-Only Fusion Glycoprotein Immunogens for Respiratory Syncytial Virus.

by Jeffrey C Boyington, M Gordon Joyce, Mallika Sastry, Guillaume B E Stewart-Jones, Man Chen, Wing-Pui Kong, Joan O Ngwuta, Paul V Thomas, Yaroslav Tsybovsky, Yongping Yang, Baoshan Zhang, Lei Chen, Aliaksandr Druz, Ivelin S Georgiev, Kiyoon Ko, Tongqing Zhou, John R Mascola, Barney S Graham, Peter D Kwong
Published 2016-01-01

Star nanoparticles delivering HIV-1 peptide minimal immunogens elicit near-native envelope antibody responses in nonhuman primates.

by Joseph R Francica, Richard Laga, Geoffrey M Lynn, Gabriela Mužíková, Ladislav Androvič, Baptiste Aussedat, William E Walkowicz, Kartika Padhan, Ramiro Andrei Ramirez-Valdez, Robert Parks, Stephen D Schmidt, Barbara J Flynn, Yaroslav Tsybovsky, Guillaume B E Stewart-Jones, Kevin O Saunders, Faezzah Baharom, Constantinos Petrovas, Barton F Haynes, Robert A Seder
Published 2019-06-01

A Cysteine Zipper Stabilizes a Pre-Fusion F Glycoprotein Vaccine for Respiratory Syncytial Virus.

by Guillaume B E Stewart-Jones, Paul V Thomas, Man Chen, Aliaksandr Druz, M Gordon Joyce, Wing-Pui Kong, Mallika Sastry, Cinque Soto, Yongping Yang, Baoshan Zhang, Lei Chen, Gwo-Yu Chuang, Ivelin S Georgiev, Jason S McLellan, Sanjay Srivatsan, Tongqing Zhou, Ulrich Baxa, John R Mascola, Barney S Graham, Peter D Kwong
Published 2015-01-01

Soluble Prefusion Closed DS-SOSIP.664-Env Trimers of Diverse HIV-1 Strains

by M. Gordon Joyce, Ivelin S. Georgiev, Yongping Yang, Aliaksandr Druz, Hui Geng, Gwo-Yu Chuang, Young Do Kwon, Marie Pancera, Reda Rawi, Mallika Sastry, Guillaume B.E. Stewart-Jones, Angela Zheng, Tongqing Zhou, Misook Choe, Joseph G. Van Galen, Rita E. Chen, Christopher R. Lees, Sandeep Narpala, Michael Chambers, Yaroslav Tsybovsky, Ulrich Baxa, Adrian B. McDermott, John R. Mascola, Peter D. Kwong
Published 2017-12-01

Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation

by Tongqing Zhou, Nicole A. Doria-Rose, Cheng Cheng, Guillaume B.E. Stewart-Jones, Gwo-Yu Chuang, Michael Chambers, Aliaksandr Druz, Hui Geng, Krisha McKee, Young Do Kwon, Sijy O’Dell, Mallika Sastry, Stephen D. Schmidt, Kai Xu, Lei Chen, Rita E. Chen, Mark K. Louder, Marie Pancera, Timothy G. Wanninger, Baoshan Zhang, Anqi Zheng, S. Katie Farney, Kathryn E. Foulds, Ivelin S. Georgiev, M. Gordon Joyce, Thomas Lemmin, Sandeep Narpala, Reda Rawi, Cinque Soto, John-Paul Todd, Chen-Hsiang Shen, Yaroslav Tsybovsky, Yongping Yang, Peng Zhao, Barton F. Haynes, Leonidas Stamatatos, Michael Tiemeyer, Lance Wells, Diana G. Scorpio, Lawrence Shapiro, Adrian B. McDermott, John R. Mascola, Peter D. Kwong
Published 2017-04-01