PARP-1 modulation of mTOR signaling in response to a DNA alkylating agent.

by Chantal Ethier, Maxime Tardif, Laura Arul, Guy G Poirier
Published 2012-01-01

Crystallographic and biochemical analysis of the mouse poly(ADP-ribose) glycohydrolase.

by Zhizhi Wang, Jean-Philippe Gagné, Guy G Poirier, Wenqing Xu
Published 2014-01-01

Proteomic and genomic analyses of antimony resistant Leishmania infantum mutant.

by Marie-Christine Brotherton, Sylvie Bourassa, Philippe Leprohon, Danielle Légaré, Guy G Poirier, Arnaud Droit, Marc Ouellette
Published 2013-01-01

DNA Damage Signalling and Repair Inhibitors: The Long-Sought-After Achilles’ Heel of Cancer

by Denis Velic, Anthony M. Couturier, Maria Tedim Ferreira, Amélie Rodrigue, Guy G. Poirier, Fabrice Fleury, Jean-Yves Masson
Published 2015-11-01

Urinary Elimination of Bile Acid Glucuronides under Severe Cholestatic Situations: Contribution of Hepatic and Renal Glucuronidation Reactions

by Martin Perreault, Ewa Wunsch, Andrzej Białek, Jocelyn Trottier, Mélanie Verreault, Patrick Caron, Guy G. Poirier, Piotr Milkiewicz, Olivier Barbier
Published 2018-01-01

Emerging roles of eraser enzymes in the dynamic control of protein ADP-ribosylation

by Julia O’Sullivan, Maria Tedim Ferreira, Jean-Philippe Gagné, Ajit K. Sharma, Michael J. Hendzel, Jean-Yves Masson, Guy G. Poirier
Published 2019-03-01

A key role for poly(ADP-ribose) polymerase 3 in ectodermal specification and neural crest development.

by Michèle Rouleau, Vishal Saxena, Amélie Rodrigue, Eric R Paquet, Abbie Gagnon, Michael J Hendzel, Jean-Yves Masson, Marc Ekker, Guy G Poirier
Published 2011-01-01

The prefoldin complex stabilizes the von Hippel-Lindau protein against aggregation and degradation.

by Franck Chesnel, Anne Couturier, Adrien Alusse, Jean-Philippe Gagné, Guy G Poirier, Dominique Jean, François-Michel Boisvert, Pauline Hascoet, Luc Paillard, Yannick Arlot-Bonnemains, Xavier Le Goff
Published 2020-11-01

Aurora kinase A localises to mitochondria to control organelle dynamics and energy production

by Giulia Bertolin, Anne-Laure Bulteau, Marie-Clotilde Alves-Guerra, Agnes Burel, Marie-Thérèse Lavault, Olivia Gavard, Stephanie Le Bras, Jean-Philippe Gagné, Guy G Poirier, Roland Le Borgne, Claude Prigent, Marc Tramier
Published 2018-08-01

ARTD1/PARP1 Negatively Regulates Glycolysis by Inhibiting Hexokinase 1 Independent of NAD+ Depletion

by Elise Fouquerel, Eva M. Goellner, Zhongxun Yu, Jean-Philippe Gagné, Michelle Barbi de Moura, Tim Feinstein, David Wheeler, Philip Redpath, Jianfeng Li, Guillermo Romero, Marie Migaud, Bennett Van Houten, Guy G. Poirier, Robert W. Sobol
Published 2014-09-01

Poly(ADP-ribose) polymerase-1 antagonizes DNA resection at double-strand breaks

by Marie-Christine Caron, Ajit K. Sharma, Julia O’Sullivan, Logan R. Myler, Maria Tedim Ferreira, Amélie Rodrigue, Yan Coulombe, Chantal Ethier, Jean-Philippe Gagné, Marie-France Langelier, John M. Pascal, Ilya J. Finkelstein, Michael J. Hendzel, Guy G. Poirier, Jean-Yves Masson
Published 2019-07-01