Dopamine transporter oligomerization involves the scaffold domain, but spares the bundle domain.

by Kumaresan Jayaraman, Alex N Morley, Daniel Szöllősi, Tsjerk A Wassenaar, Harald H Sitte, Thomas Stockner
Published 2018-06-01

Active transport of rhodamine 123 by the human multidrug transporter P‐glycoprotein involves two independent outer gates

by Fauzia Nasim, Diethart Schmid, Gergely Szakács, Azmat Sohail, Harald H. Sitte, Peter Chiba, Thomas Stockner
Published 2020-04-01

Handling of intracellular K+ determines voltage dependence of plasmalemmal monoamine transporter function

by Shreyas Bhat, Marco Niello, Klaus Schicker, Christian Pifl, Harald H Sitte, Michael Freissmuth, Walter Sandtner
Published 2021-06-01

Direct PIP2 binding mediates stable oligomer formation of the serotonin transporter

by Andreas Anderluh, Tina Hofmaier, Enrico Klotzsch, Oliver Kudlacek, Thomas Stockner, Harald H. Sitte, Gerhard J. Schütz
Published 2017-01-01

Mutational analysis of the high-affinity zinc binding site validates a refined human dopamine transporter homology model.

by Thomas Stockner, Therese R Montgomery, Oliver Kudlacek, Rene Weissensteiner, Gerhard F Ecker, Michael Freissmuth, Harald H Sitte
Published 2013-01-01

Allosterically Linked Binding Sites in Serotonin Transporter Revealed by Single Molecule Force Spectroscopy

by Rong Zhu, Walter Sandtner, Joan E. A. Ahiable, Amy Hauck Newman, Michael Freissmuth, Harald H. Sitte, Peter Hinterdorfer
Published 2020-06-01

Refinement of the Central Steps of Substrate Transport by the Aspartate Transporter GltPh: Elucidating the Role of the Na2 Sodium Binding Site.

by SanthoshKannan Venkatesan, Kusumika Saha, Azmat Sohail, Walter Sandtner, Michael Freissmuth, Gerhard F Ecker, Harald H Sitte, Thomas Stockner
Published 2015-10-01

Transition metal ion FRET uncovers K+ regulation of a neurotransmitter/sodium symporter

by Christian B. Billesbølle, Jonas S. Mortensen, Azmat Sohail, Solveig G. Schmidt, Lei Shi, Harald H. Sitte, Ulrik Gether, Claus J. Loland
Published 2016-09-01

Effects of Hydroxylated Mephedrone Metabolites on Monoamine Transporter Activity in vitro

by Marco Niello, Daniela Cintulová, Philip Raithmayr, Marion Holy, Kathrin Jäntsch, Claire Colas, Gerhard F. Ecker, Harald H. Sitte, Marko D. Mihovilovic
Published 2021-04-01

Constitutive Endocytosis of the Neuronal Glutamate Transporter Excitatory Amino Acid Transporter-3 Requires ARFGAP1

by Kusumika Saha, Kusumika Saha, Jae-Won Yang, Tina Hofmaier, SanthoshKannan Venkatesan, Thomas Steinkellner, Oliver Kudlacek, Sonja Sucic, Michael Freissmuth, Harald H. Sitte
Published 2021-05-01

Cell-Based Radiotracer Binding and Uptake Inhibition Assays: A Comparison of In Vitro Methods to Assess the Potency of Drugs That Target Monoamine Transporters

by Marija Ilic, Marija Ilic, Marija Ilic, Marion Holy, Kathrin Jaentsch, Matthias E. Liechti, Gert Lubec, Michael H. Baumann, Harald H. Sitte, Dino Luethi, Dino Luethi
Published 2020-05-01

The Environment Shapes the Inner Vestibule of LeuT.

by Azmat Sohail, Kumaresan Jayaraman, Santhoshkannan Venkatesan, Kamil Gotfryd, Markus Daerr, Ulrik Gether, Claus J Loland, Klaus T Wanner, Michael Freissmuth, Harald H Sitte, Walter Sandtner, Thomas Stockner
Published 2016-11-01

R-Modafinil exerts weak effects on spatial memory acquisition and dentate gyrus synaptic plasticity.

by Bharanidharan Shanmugasundaram, Yogesh D Aher, Jana Aradska, Marija Ilic, Daniel Daba Feyissa, Predrag Kalaba, Nilima Y Aher, Vladimir Dragacevic, Babak Saber Marouf, Thierry Langer, Harald H Sitte, Harald Hoeger, Gert Lubec, Volker Korz
Published 2017-01-01

A novel heterocyclic compound CE-104 enhances spatial working memory in the radial arm maze in rats and modulates the dopaminergic system

by Yogesh D Aher, Saraswathi eSubramaniyan, Bharanidharan eShanmugasundaram, Ajinkya eSase, Sivaprakasam R Saroja, Marion eHoly, Harald eHoeger, Tetyana eBeryozkina, Harald H Sitte, Johann Jakob Leban, Gert eLubec
Published 2016-02-01

Insight into the Anticancer Activity of Copper(II) 5-Methylenetrimethylammonium-Thiosemicarbazonates and Their Interaction with Organic Cation Transporters

by Miljan N. M. Milunović, Oleg Palamarciuc, Angela Sirbu, Sergiu Shova, Dan Dumitrescu, Dana Dvoranová, Peter Rapta, Tatsiana V. Petrasheuskaya, Eva A. Enyedy, Gabriella Spengler, Marija Ilic, Harald H. Sitte, Gert Lubec, Vladimir B. Arion
Published 2020-08-01

The effect of modafinil on the rat dopamine transporter and dopamine receptors D1-D3 paralleling cognitive enhancement in the radial arm maze

by Yasemin eKarabacak, Sunetra eSase, Yogesh eAher, Ajinkya eSase, Sivaprakasam eSaroja, Ana eCicvaric, Harald eHoeger, Michael eBerger, Vasiliy eBakulev, Harald H Sitte, Johann eLeban, Francisco J Monje, Gert eLubec
Published 2015-08-01

Platelet serotonin transporter function predicts default-mode network activity.

by Christian Scharinger, Ulrich Rabl, Christian H Kasess, Bernhard M Meyer, Tina Hofmaier, Kersten Diers, Lucie Bartova, Gerald Pail, Wolfgang Huf, Zeljko Uzelac, Beate Hartinger, Klaudius Kalcher, Thomas Perkmann, Helmuth Haslacher, Andreas Meyer-Lindenberg, Siegfried Kasper, Michael Freissmuth, Christian Windischberger, Matthäus Willeit, Rupert Lanzenberger, Harald Esterbauer, Burkhard Brocke, Ewald Moser, Harald H Sitte, Lukas Pezawas
Published 2014-01-01