Kinetic Models of Secondary Active Transporters

by Verena Burtscher, Klaus Schicker, Michael Freissmuth, Walter Sandtner
Published 2019-10-01

Big Lessons from Tiny Flies: Drosophila melanogaster as a Model to Explore Dysfunction of Dopaminergic and Serotonergic Neurotransmitter Systems

by Ameya Sanjay Kasture, Thomas Hummel, Sonja Sucic, Michael Freissmuth
Published 2018-06-01

A label-free approach to detect ligand binding to cell surface proteins in real time

by Verena Burtscher, Matej Hotka, Yang Li, Michael Freissmuth, Walter Sandtner
Published 2018-04-01

The Creatine Transporter Unfolded: A Knotty Premise in the Cerebral Creatine Deficiency Syndrome

by Clemens V. Farr, Ali El-Kasaby, Michael Freissmuth, Sonja Sucic
Published 2020-10-01

Relax, Cool Down and Scaffold: How to Restore Surface Expression of Folding-Deficient Mutant GPCRs and SLC6 Transporters

by H.M. Mazhar Asjad, Shahrooz Nasrollahi-Shirazi, Sonja Sucic, Michael Freissmuth, Christian Nanoff
Published 2017-11-01

Descriptors of Secondary Active Transporter Function and How They Relate to Partial Reactions in the Transport Cycle

by Klaus Schicker, Shreyas Bhat, Clemens Farr, Verena Burtscher, Andreas Horner, Michael Freissmuth, Walter Sandtner
Published 2021-03-01

Handling of intracellular K+ determines voltage dependence of plasmalemmal monoamine transporter function

by Shreyas Bhat, Marco Niello, Klaus Schicker, Christian Pifl, Harald H Sitte, Michael Freissmuth, Walter Sandtner
Published 2021-06-01

Mutational analysis of the high-affinity zinc binding site validates a refined human dopamine transporter homology model.

by Thomas Stockner, Therese R Montgomery, Oliver Kudlacek, Rene Weissensteiner, Gerhard F Ecker, Michael Freissmuth, Harald H Sitte
Published 2013-01-01

Allosterically Linked Binding Sites in Serotonin Transporter Revealed by Single Molecule Force Spectroscopy

by Rong Zhu, Walter Sandtner, Joan E. A. Ahiable, Amy Hauck Newman, Michael Freissmuth, Harald H. Sitte, Peter Hinterdorfer
Published 2020-06-01

Refinement of the Central Steps of Substrate Transport by the Aspartate Transporter GltPh: Elucidating the Role of the Na2 Sodium Binding Site.

by SanthoshKannan Venkatesan, Kusumika Saha, Azmat Sohail, Walter Sandtner, Michael Freissmuth, Gerhard F Ecker, Harald H Sitte, Thomas Stockner
Published 2015-10-01

Assessing the Accuracy of Sales Forecasts Submitted by Pharmaceutical Companies Applying for Reimbursement in Austria

by Michael Kossmeier, Madeleine Themanns, Lena Hatapoglu, Bernhard Kogler, Simon Keuerleber, Jutta Lichtenecker, Robert Sauermann, Anna Bucsics, Michael Freissmuth, Eva Zebedin-Brandl
Published 2021-08-01

Optimization of an Antibody Light Chain Framework Enhances Expression, Biophysical Properties and Pharmacokinetics

by Patrice Douillard, Michael Freissmuth, Gerhard Antoine, Michael Thiele, Daniel Fleischanderl, Peter Matthiessen, Dirk Voelkel, Randolf J. Kerschbaumer, Friedrich Scheiflinger, Nicolas Sabarth
Published 2019-09-01

Binding and neutralization of C. difficile toxins A and B by purified clinoptilolite-tuff.

by Carmen Ranftler, Dietmar Nagl, Andreas Sparer, Andreas Röhrich, Michael Freissmuth, Ali El-Kasaby, Shahrooz Nasrollahi Shirazi, Florian Koban, Cornelius Tschegg, Stephane Nizet
Published 2021-01-01

Identification and characterization of the Fasciola hepatica sodium- and chloride-dependent taurine transporter.

by Bulut Hamali, Sandra Pichler, Elisabeth Wischnitzki, Klaus Schicker, Melanie Burger, Marion Holy, Kathrin Jaentsch, Martina Molin, Eva Maria Sehr, Oliver Kudlacek, Michael Freissmuth
Published 2018-04-01

Constitutive Endocytosis of the Neuronal Glutamate Transporter Excitatory Amino Acid Transporter-3 Requires ARFGAP1

by Kusumika Saha, Kusumika Saha, Jae-Won Yang, Tina Hofmaier, SanthoshKannan Venkatesan, Thomas Steinkellner, Oliver Kudlacek, Sonja Sucic, Michael Freissmuth, Harald H. Sitte
Published 2021-05-01

Concomitant oral intake of purified clinoptilolite tuff (G-PUR) reduces enteral lead uptake in healthy humans

by Karolina Samekova, Christa Firbas, Johanna Irrgeher, Christine Opper, Thomas Prohaska, Anika Retzmann, Cornelius Tschegg, Claudia Meisslitzer, Anastassiya Tchaikovsky, Ghazaleh Gouya, Michael Freissmuth, Michael Wolzt
Published 2021-07-01

The Environment Shapes the Inner Vestibule of LeuT.

by Azmat Sohail, Kumaresan Jayaraman, Santhoshkannan Venkatesan, Kamil Gotfryd, Markus Daerr, Ulrik Gether, Claus J Loland, Klaus T Wanner, Michael Freissmuth, Harald H Sitte, Walter Sandtner, Thomas Stockner
Published 2016-11-01

PI3Kδ is essential for tumor clearance mediated by cytotoxic T lymphocytes.

by Eva Maria Putz, Eva Maria Putz, Michaela Prchal-Murphy, Olivia Annabella Simma, Florian Forster, Xaver Koenig, Hannes Stockinger, Roland P Piekorz, Michael Freissmuth, Mathias Müller, Veronika Sexl, Eva Zebedin-Brandl
Published 2012-01-01

Platelet serotonin transporter function predicts default-mode network activity.

by Christian Scharinger, Ulrich Rabl, Christian H Kasess, Bernhard M Meyer, Tina Hofmaier, Kersten Diers, Lucie Bartova, Gerald Pail, Wolfgang Huf, Zeljko Uzelac, Beate Hartinger, Klaudius Kalcher, Thomas Perkmann, Helmuth Haslacher, Andreas Meyer-Lindenberg, Siegfried Kasper, Michael Freissmuth, Christian Windischberger, Matthäus Willeit, Rupert Lanzenberger, Harald Esterbauer, Burkhard Brocke, Ewald Moser, Harald H Sitte, Lukas Pezawas
Published 2014-01-01