Patched Knockout Mouse Models of Basal Cell Carcinoma

by Frauke Nitzki, Marco Becker, Anke Frommhold, Walter Schulz-Schaeffer, Heidi Hahn
Published 2012-01-01

Genetic Activation of Hedgehog Signaling Unbalances the Rate of Neural Stem Cell Renewal by Increasing Symmetric Divisions

by Julien Ferent, Loïc Cochard, Hélène Faure, Maurizio Taddei, Heidi Hahn, Martial Ruat, Elisabeth Traiffort
Published 2014-08-01

The hedgehog receptor patched1 in T cells is dispensable for adaptive immunity in mice.

by Kai D Michel, Anja Uhmann, Ralf Dressel, Jens van den Brandt, Heidi Hahn, Holger M Reichardt
Published 2013-01-01

Hedgehog Controls Quiescence and Activation of Neural Stem Cells in the Adult Ventricular-Subventricular Zone

by Mathieu Daynac, Linda Tirou, Hélène Faure, Marc-André Mouthon, Laurent R. Gauthier, Heidi Hahn, François D. Boussin, Martial Ruat
Published 2016-10-01

Calcitriol Inhibits Hedgehog Signaling and Induces Vitamin D Receptor Signaling and Differentiation in the Patched Mouse Model of Embryonal Rhabdomyosarcoma

by Anja Uhmann, Hannah Niemann, Bérénice Lammering, Cornelia Henkel, Ina Heß, Albert Rosenberger, Christian Dullin, Anke Schraepler, Walter Schulz-Schaeffer, Heidi Hahn
Published 2012-01-01

Different Response of Ptch Mutant and Ptch Wildtype Rhabdomyosarcoma Toward SMO and PI3K Inhibitors

by Natalie Geyer, Rosalie Ridzewski, Julia Bauer, Maria Kuzyakova, Kai Dittmann, Christian Dullin, Albert Rosenberger, Hans-Ulrich Schildhaus, Anja Uhmann, Simone Fulda, Heidi Hahn
Published 2018-09-01

Spreading of Isolated <i>Ptch</i> Mutant Basal Cell Carcinoma Precursors Is Physiologically Suppressed and Counteracts Tumor Formation in Mice

by Nadine Brandes, Slavica Hristomanova Mitkovska, Dominik Simon Botermann, Wiebke Maurer, Anna Müllen, Hanna Scheile, Sebastian Zabel, Anke Frommhold, Ina Heß, Heidi Hahn, Anja Uhmann
Published 2020-12-01

PI3K inhibition enhances doxorubicin-induced apoptosis in sarcoma cells.

by Diana Marklein, Ulrike Graab, Ivonne Naumann, Tiandong Yan, Rosalie Ridzewski, Frauke Nitzki, Albert Rosenberger, Kai Dittmann, Jürgen Wienands, Leszek Wojnowski, Simone Fulda, Heidi Hahn
Published 2012-01-01

Depletion of cutaneous macrophages and dendritic cells promotes growth of basal cell carcinoma in mice.

by Simone König, Frauke Nitzki, Anja Uhmann, Kai Dittmann, Jennifer Theiss-Suennemann, Markus Herrmann, Holger M Reichardt, Reto Schwendener, Tobias Pukrop, Walter Schulz-Schaeffer, Heidi Hahn
Published 2014-01-01

Regulation and Role of GLI1 in Cutaneous Squamous Cell Carcinoma Pathogenesis

by Joanna Pyczek, Natalia Khizanishvili, Maria Kuzyakova, Sebastian Zabel, Julia Bauer, Frauke Nitzki, Steffen Emmert, Michael P. Schön, Petra Boukamp, Hans-Ulrich Schildhaus, Anja Uhmann, Heidi Hahn
Published 2019-12-01

Canonical WNT/β-Catenin Signaling Plays a Subordinate Role in Rhabdomyosarcomas

by Nada Ragab, Florian Viehweger, Florian Viehweger, Julia Bauer, Natalie Geyer, Mingya Yang, Anna Seils, Djeda Belharazem, Felix H. Brembeck, Hans-Ulrich Schildhaus, Alexander Marx, Heidi Hahn, Katja Simon-Keller
Published 2018-12-01

Mechanochemical control of epidermal stem cell divisions by B-plexins

by Chen Jiang, Ahsan Javed, Laura Kaiser, Michele M. Nava, Rui Xu, Dominique T. Brandt, Dandan Zhao, Benjamin Mayer, Javier Fernández-Baldovinos, Luping Zhou, Carsten Höß, Kovilen Sawmynaden, Arkadiusz Oleksy, David Matthews, Lee S. Weinstein, Heidi Hahn, Hermann-Josef Gröne, Peter L. Graumann, Carien M. Niessen, Stefan Offermanns, Sara A. Wickström, Thomas Worzfeld
Published 2021-02-01

Indian Hedgehog Suppresses a Stromal Cell–Driven Intestinal Immune Response

by B. Florien Westendorp, Nikè V.J.A. Büller, Olga N. Karpus, Willemijn A. van Dop, Jan Koster, Rogier Versteeg, Pim J. Koelink, Clinton Y. Snel, Sander Meisner, Joris J.T.H. Roelofs, Anja Uhmann, Emiel Ver Loren van Themaat, Jarom Heijmans, Heidi Hahn, Vanesa Muncan, Manon E. Wildenberg, Gijs R. van den Brink
Published 2018-01-01