Intratumour diversity of chromosome copy numbers in neuroblastoma mediated by on-going chromosome loss from a polyploid state.

by Gisela Lundberg, Yuesheng Jin, Daniel Sehic, Ingrid Øra, Rogier Versteeg, David Gisselsson
Published 2013-01-01

Joint binding of OTX2 and MYC in promotor regions is associated with high gene expression in medulloblastoma.

by Jens Bunt, Nancy E Hasselt, Danny A Zwijnenburg, Jan Koster, Rogier Versteeg, Marcel Kool
Published 2011-01-01

Targeting CDKs with Roscovitine Increases Sensitivity to DNA Damaging Drugs of Human Osteosarcoma Cells.

by Serena Vella, Elisa Tavanti, Claudia Maria Hattinger, Marilù Fanelli, Rogier Versteeg, Jan Koster, Piero Picci, Massimo Serra
Published 2016-01-01

CD44 expression in intestinal epithelium and colorectal cancer is independent of p53 status.

by Jurrit Zeilstra, Sander P J Joosten, Louis Vermeulen, Jan Koster, Jan Paul Medema, Rogier Versteeg, Marcel Spaargaren, Steven T Pals
Published 2013-01-01

DNA-Dependent Protein Kinase As Molecular Target for Radiosensitization of Neuroblastoma Cells.

by M Emmy M Dolman, Ida van der Ploeg, Jan Koster, Laurel Tabe Bate-Eya, Rogier Versteeg, Huib N Caron, Jan J Molenaar
Published 2015-01-01

Efficient double fragmentation ChIP-seq provides nucleotide resolution protein-DNA binding profiles.

by Michal Mokry, Pantelis Hatzis, Ewart de Bruijn, Jan Koster, Rogier Versteeg, Jurian Schuijers, Marc van de Wetering, Victor Guryev, Hans Clevers, Edwin Cuppen
Published 2010-11-01

Robust selection of cancer survival signatures from high-throughput genomic data using two-fold subsampling.

by Sangkyun Lee, Jörg Rahnenführer, Michel Lang, Katleen De Preter, Pieter Mestdagh, Jan Koster, Rogier Versteeg, Raymond L Stallings, Luigi Varesio, Shahab Asgharzadeh, Johannes H Schulte, Kathrin Fielitz, Melanie Schwermer, Katharina Morik, Alexander Schramm
Published 2014-01-01

CASP8 SNP D302H (rs1045485) is associated with worse survival in MYCN-amplified neuroblastoma patients.

by Ali Rihani, Bram De Wilde, Fjoralba Zeka, Geneviève Laureys, Nadine Francotte, Gian Paolo Tonini, Simona Coco, Rogier Versteeg, Rosa Noguera, Johannes H Schulte, Angelika Eggert, Raymond L Stallings, Frank Speleman, Jo Vandesompele, Tom Van Maerken
Published 2014-01-01

Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features.

by Marcel Kool, Jan Koster, Jens Bunt, Nancy E Hasselt, Arjan Lakeman, Peter van Sluis, Dirk Troost, Netteke Schouten-van Meeteren, Huib N Caron, Jacqueline Cloos, Alan Mrsić, Bauke Ylstra, Wieslawa Grajkowska, Wolfgang Hartmann, Torsten Pietsch, David Ellison, Steven C Clifford, Rogier Versteeg
Published 2008-08-01

A NOTCH feed-forward loop drives reprogramming from adrenergic to mesenchymal state in neuroblastoma

by Tim van Groningen, Nurdan Akogul, Ellen M. Westerhout, Alvin Chan, Nancy E. Hasselt, Danny A. Zwijnenburg, Marloes Broekmans, Peter Stroeken, Franciska Haneveld, Gerrit K. J. Hooijer, C. Dilara Savci-Heijink, Arjan Lakeman, Richard Volckmann, Peter van Sluis, Linda J. Valentijn, Jan Koster, Rogier Versteeg, Johan van Nes
Published 2019-04-01

Indian Hedgehog Suppresses a Stromal Cell–Driven Intestinal Immune Response

by B. Florien Westendorp, Nikè V.J.A. Büller, Olga N. Karpus, Willemijn A. van Dop, Jan Koster, Rogier Versteeg, Pim J. Koelink, Clinton Y. Snel, Sander Meisner, Joris J.T.H. Roelofs, Anja Uhmann, Emiel Ver Loren van Themaat, Jarom Heijmans, Heidi Hahn, Vanesa Muncan, Manon E. Wildenberg, Gijs R. van den Brink
Published 2018-01-01

TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets

by Bieke Decaesteker, Geertrui Denecker, Christophe Van Neste, Emmy M. Dolman, Wouter Van Loocke, Moritz Gartlgruber, Carolina Nunes, Fanny De Vloed, Pauline Depuydt, Karen Verboom, Dries Rombaut, Siebe Loontiens, Jolien De Wyn, Waleed M. Kholosy, Bianca Koopmans, Anke H. W. Essing, Carl Herrmann, Daniel Dreidax, Kaat Durinck, Dieter Deforce, Filip Van Nieuwerburgh, Anton Henssen, Rogier Versteeg, Valentina Boeva, Gudrun Schleiermacher, Johan van Nes, Pieter Mestdagh, Suzanne Vanhauwaert, Johannes H. Schulte, Frank Westermann, Jan J. Molenaar, Katleen De Preter, Frank Speleman
Published 2018-11-01

A G316A Polymorphism in the Ornithine Decarboxylase Gene Promoter Modulates MYCN-Driven Childhood Neuroblastoma

by Laura D. Gamble, Stefania Purgato, Michelle J. Henderson, Simone Di Giacomo, Amanda J. Russell, Paolo Pigini, Jayne Murray, Emanuele Valli, Giorgio Milazzo, Federico M. Giorgi, Mark Cowley, Lesley J. Ashton, Jaydutt Bhalshankar, Gudrun Schleiermacher, Ali Rihani, Tom Van Maerken, Jo Vandesompele, Frank Speleman, Rogier Versteeg, Jan Koster, Angelika Eggert, Rosa Noguera, Raymond L. Stallings, Gian Paolo Tonini, Kwun Fong, Zalman Vaksman, Sharon J. Diskin, John M. Maris, Wendy B. London, Glenn M. Marshall, David S. Ziegler, Michael D. Hogarty, Giovanni Perini, Murray D. Norris, Michelle Haber
Published 2021-04-01

A cancer drug atlas enables synergistic targeting of independent drug vulnerabilities

by Ravi S. Narayan, Piet Molenaar, Jian Teng, Fleur M. G. Cornelissen, Irene Roelofs, Renee Menezes, Rogier Dik, Tonny Lagerweij, Yoran Broersma, Naomi Petersen, Jhon Alexander Marin Soto, Eelke Brands, Philip van Kuiken, Maria C. Lecca, Kristiaan J. Lenos, Sjors G. J. G. In ‘t Veld, Wessel van Wieringen, Frederick F. Lang, Erik Sulman, Roel Verhaak, Brigitta G. Baumert, Lucas J. A. Stalpers, Louis Vermeulen, Colin Watts, David Bailey, Ben J. Slotman, Rogier Versteeg, David Noske, Peter Sminia, Bakhos A. Tannous, Tom Wurdinger, Jan Koster, Bart A. Westerman
Published 2020-06-01