The Effect of Wnt Pathway Modulators on Human iPSC-Derived Pancreatic Beta Cell Maturation

by Heidrun Vethe, Luiza Ghila, Magnus Berle, Magnus Berle, Laurence Hoareau, Øystein A. Haaland, Hanne Scholz, Hanne Scholz, Joao A. Paulo, Simona Chera, Helge Ræder, Helge Ræder
Published 2019-05-01

Springboard to an academic career-A national medical student research program.

by Geir W Jacobsen, Helge Ræder, Marianne H Stien, Ludvig A Munthe, Vegard Skogen
Published 2018-01-01

In vivo Environment Swiftly Restricts Human Pancreatic Progenitors Toward Mono-Hormonal Identity via a HNF1A/HNF4A Mechanism

by Thomas Aga Legøy, Andreas F. Mathisen, Zaidon Salim, Heidrun Vethe, Yngvild Bjørlykke, Shadab Abadpour, Shadab Abadpour, Joao A. Paulo, Hanne Scholz, Hanne Scholz, Helge Ræder, Helge Ræder, Luiza Ghila, Simona Chera
Published 2020-02-01

Bioinformatic Analyses of miRNA–mRNA Signature during hiPSC Differentiation towards Insulin-Producing Cells upon HNF4α Mutation

by Luiza Ghila, Yngvild Bjørlykke, Thomas Aga Legøy, Heidrun Vethe, Kenichiro Furuyama, Simona Chera, Helge Ræder
Published 2020-06-01

Probing the missing mature β-cell proteomic landscape in differentiating patient iPSC-derived cells

by Heidrun Vethe, Yngvild Bjørlykke, Luiza M. Ghila, Joao A. Paulo, Hanne Scholz, Steven P. Gygi, Simona Chera, Helge Ræder
Published 2017-07-01

Early Developmental Perturbations in a Human Stem Cell Model of MODY5/HNF1B Pancreatic Hypoplasia

by Adrian Kee Keong Teo, Hwee Hui Lau, Ivan Achel Valdez, Ercument Dirice, Erling Tjora, Helge Raeder, Rohit N. Kulkarni
Published 2016-03-01

Chronically Elevated Exogenous Glucose Elicits Antipodal Effects on the Proteome Signature of Differentiating Human iPSC-Derived Pancreatic Progenitors

by Luiza Ghila, Thomas Aga Legøy, Andreas Frøslev Mathisen, Shadab Abadpour, Joao A. Paulo, Hanne Scholz, Helge Ræder, Simona Chera
Published 2021-04-01

Reprogrammed Cells Display Distinct Proteomic Signatures Associated with Colony Morphology Variability

by Yngvild Bjørlykke, Anne M. Søviknes, Laurence Hoareau, Heidrun Vethe, Andreas F. Mathisen, Simona Chera, Marc Vaudel, Luiza M. Ghila, Helge Ræder
Published 2019-01-01

Induction of alveolar and bronchiolar phenotypes in human lung organoids

by Laurence Hoareau, Agnete S. T. Engelsen, Marianne Aanerud, Maria Paula Ramnefjell, Pirjo‐Riitta Salminen, Fabian Gärtner, Thomas Halvorsen, Helge Ræder, Mariann H. L. Bentsen
Published 2021-06-01

The Chromosome 9p21 CVD- and T2D-Associated Regions in a Norwegian Population (The HUNT2 Survey)

by Øyvind Helgeland, Jens K. Hertel, Anders Molven, Helge Ræder, Carl G. P. Platou, Kristian Midthjell, Kristian Hveem, Ottar Nygård, Pål R. Njølstad, Stefan Johansson
Published 2015-01-01

HNF4A Haploinsufficiency in MODY1 Abrogates Liver and Pancreas Differentiation from Patient-Derived Induced Pluripotent Stem Cells

by Natasha Hui Jin Ng, Joanita Binte Jasmen, Chang Siang Lim, Hwee Hui Lau, Vidhya Gomathi Krishnan, Juned Kadiwala, Rohit N. Kulkarni, Helge Ræder, Ludovic Vallier, Shawn Hoon, Adrian Kee Keong Teo
Published 2019-06-01

Absence of diabetes and pancreatic exocrine dysfunction in a transgenic model of carboxyl-ester lipase-MODY (maturity-onset diabetes of the young).

by Helge Ræder, Mette Vesterhus, Abdelfattah El Ouaamari, Joao A Paulo, Fiona E McAllister, Chong Wee Liew, Jiang Hu, Dan Kawamori, Anders Molven, Steven P Gygi, Pål R Njølstad, C Ronald Kahn, Rohit N Kulkarni
Published 2013-01-01