Engineering Translation Components Improve Incorporation of Exotic Amino Acids

by Takayuki Katoh, Hiroaki Suga
Published 2019-01-01

Technologies for the Synthesis of mRNA-Encoding Libraries and Discovery of Bioactive Natural Product-Inspired Non-Traditional Macrocyclic Peptides

by Hiroaki Suga, Toby Passioura, Kenichiro Ito
Published 2013-03-01

Structural Features and Binding Modes of Thioether-Cyclized Peptide Ligands

by Manuel E. Otero-Ramirez, Toby Passioura, Hiroaki Suga
Published 2018-12-01

Posttranslational chemical installation of azoles into translated peptides

by Haruka Tsutsumi, Tomohiro Kuroda, Hiroyuki Kimura, Yuki Goto, Hiroaki Suga
Published 2021-01-01

Cyclic Peptide-Based Biologics Regulating HGF-MET

by Hiroki Sato, Ryu Imamura, Hiroaki Suga, Kunio Matsumoto, Katsuya Sakai
Published 2020-10-01

Essential structural elements in tRNAPro for EF-P-mediated alleviation of translation stalling

by Takayuki Katoh, Ingo Wohlgemuth, Masanobu Nagano, Marina V. Rodnina, Hiroaki Suga
Published 2016-05-01

Pyrrole-Mediated Peptide Cyclization Identified through Genetically Reprogrammed Peptide Synthesis

by Klaas W. Decoene, Willem Vannecke, Toby Passioura, Hiroaki Suga, Annemieke Madder
Published 2018-10-01

Recent Developments of Engineered Translational Machineries for the Incorporation of Non-Canonical Amino Acids into Polypeptides

by Naohiro Terasaka, Yoshihiko Iwane, Anna-Skrollan Geiermann, Yuki Goto, Hiroaki Suga
Published 2015-03-01

A Macrocyclic Peptide that Serves as a Cocrystallization Ligand and Inhibits the Function of a MATE Family Transporter

by Hiroaki Suga, Takayuki Katoh, Osamu Nureki, Christopher J. Hipolito, Yoshiki Tanaka
Published 2013-08-01

Methodologies for Backbone Macrocyclic Peptide Synthesis Compatible With Screening Technologies

by Koki Shinbara, Wenyu Liu, Renier Herman Pieter van Neer, Takayuki Katoh, Hiroaki Suga
Published 2020-06-01

Prognostic significance of vitamin D receptor polymorphisms in head and neck squamous cell carcinoma.

by Takanori Hama, Chihiro Norizoe, Hiroaki Suga, Takeshi Mimura, Takakuni Kato, Hiroshi Moriyama, Mitsuyoshi Urashima
Published 2011-01-01

MET Activation by a Macrocyclic Peptide Agonist that Couples to Biological Responses Differently from HGF in a Context-Dependent Manner

by Wenyu Miao, Katsuya Sakai, Ryu Imamura, Kenichiro Ito, Hiroaki Suga, Tetsushi Sakuma, Takashi Yamamoto, Kunio Matsumoto
Published 2018-10-01

De novo macrocyclic peptides dissect energy coupling of a heterodimeric ABC transporter by multimode allosteric inhibition

by Erich Stefan, Richard Obexer, Susanne Hofmann, Khanh Vu Huu, Yichao Huang, Nina Morgner, Hiroaki Suga, Robert Tampé
Published 2021-04-01

Minimal lactazole scaffold for in vitro thiopeptide bioengineering

by Alexander A. Vinogradov, Morito Shimomura, Yuki Goto, Taro Ozaki, Shumpei Asamizu, Yoshinori Sugai, Hiroaki Suga, Hiroyasu Onaka
Published 2020-05-01

Dissection of goadsporin biosynthesis by in vitro reconstitution leading to designer analogues expressed in vivo

by Taro Ozaki, Kona Yamashita, Yuki Goto, Morito Shimomura, Shohei Hayashi, Shumpei Asamizu, Yoshinori Sugai, Haruo Ikeda, Hiroaki Suga, Hiroyasu Onaka
Published 2017-02-01

Lasso-grafting of macrocyclic peptide pharmacophores yields multi-functional proteins

by Emiko Mihara, Satoshi Watanabe, Nasir K. Bashiruddin, Nozomi Nakamura, Kyoko Matoba, Yumi Sano, Rumit Maini, Yizhen Yin, Katsuya Sakai, Takao Arimori, Kunio Matsumoto, Hiroaki Suga, Junichi Takagi
Published 2021-03-01

Macrocycle peptides delineate locked-open inhibition mechanism for microorganism phosphoglycerate mutases

by Hao Yu, Patricia Dranchak, Zhiru Li, Ryan MacArthur, Matthew S. Munson, Nurjahan Mehzabeen, Nathan J. Baird, Kevin P. Battalie, David Ross, Scott Lovell, Clotilde K. S. Carlow, Hiroaki Suga, James Inglese
Published 2017-04-01

Interactions between serum vitamin D levels and vitamin D receptor gene FokI polymorphisms for renal function in patients with type 2 diabetes.

by Keitaro Yokoyama, Akio Nakashima, Mitsuyoshi Urashima, Hiroaki Suga, Takeshi Mimura, Yasuo Kimura, Yasushi Kanazawa, Tamotsu Yokota, Masaya Sakamoto, Sho Ishizawa, Rimei Nishimura, Hideaki Kurata, Yudo Tanno, Katsuyoshi Tojo, Shigeru Kageyama, Ichiro Ohkido, Kazunori Utsunomiya, Tatsuo Hosoya
Published 2012-01-01

Highly selective inhibition of histone demethylases by de novo macrocyclic peptides

by Akane Kawamura, Martin Münzel, Tatsuya Kojima, Clarence Yapp, Bhaskar Bhushan, Yuki Goto, Anthony Tumber, Takayuki Katoh, Oliver N. F. King, Toby Passioura, Louise J. Walport, Stephanie B. Hatch, Sarah Madden, Susanne Müller, Paul E. Brennan, Rasheduzzaman Chowdhury, Richard J. Hopkinson, Hiroaki Suga, Christopher J. Schofield
Published 2017-04-01

Macrocyclic peptides exhibit antiviral effects against influenza virus HA and prevent pneumonia in animal models

by Makoto Saito, Yasushi Itoh, Fumihiko Yasui, Tsubasa Munakata, Daisuke Yamane, Makoto Ozawa, Risa Ito, Takayuki Katoh, Hirohito Ishigaki, Misako Nakayama, Shintaro Shichinohe, Kenzaburo Yamaji, Naoki Yamamoto, Ai Ikejiri, Tomoko Honda, Takahiro Sanada, Yoshihiro Sakoda, Hiroshi Kida, Thi Quynh Mai Le, Yoshihiro Kawaoka, Kazumasa Ogasawara, Kyoko Tsukiyama-Kohara, Hiroaki Suga, Michinori Kohara
Published 2021-05-01