TargetDB: A target information aggregation tool and tractability predictor.

by Stephane De Cesco, John B Davis, Paul E Brennan
Published 2020-01-01

A phenotypic high-content, high-throughput screen identifies inhibitors of NLRP3 inflammasome activation

by Sohaib Nizami, Val Millar, Kanisa Arunasalam, Tryfon Zarganes-Tzitzikas, David Brough, Gary Tresadern, Paul E. Brennan, John B. Davis, Daniel Ebner, Elena Di Daniel
Published 2021-07-01

BRD3 and BRD4 BET Bromodomain Proteins Differentially Regulate Skeletal Myogenesis

by Thomas C. Roberts, Usue Etxaniz, Alessandra Dall’Agnese, Shwu-Yuan Wu, Cheng-Ming Chiang, Paul E. Brennan, Matthew J. A. Wood, Pier Lorenzo Puri
Published 2017-07-01

A chemical toolbox for the study of bromodomains and epigenetic signaling

by Qin Wu, David Heidenreich, Stanley Zhou, Suzanne Ackloo, Andreas Krämer, Kiran Nakka, Evelyne Lima-Fernandes, Genevieve Deblois, Shili Duan, Ravi N. Vellanki, Fengling Li, Masoud Vedadi, Jeffrey Dilworth, Mathieu Lupien, Paul E. Brennan, Cheryl H. Arrowsmith, Susanne Müller, Oleg Fedorov, Panagis Filippakopoulos, Stefan Knapp
Published 2019-04-01

Highly selective inhibition of histone demethylases by de novo macrocyclic peptides

by Akane Kawamura, Martin Münzel, Tatsuya Kojima, Clarence Yapp, Bhaskar Bhushan, Yuki Goto, Anthony Tumber, Takayuki Katoh, Oliver N. F. King, Toby Passioura, Louise J. Walport, Stephanie B. Hatch, Sarah Madden, Susanne Müller, Paul E. Brennan, Rasheduzzaman Chowdhury, Richard J. Hopkinson, Hiroaki Suga, Christopher J. Schofield
Published 2017-04-01

Male sex chromosomal complement exacerbates the pathogenicity of Th17 cells in a chronic model of central nervous system autoimmunity

by Prenitha Mercy Ignatius Arokia Doss, Muhammad Umair, Joanie Baillargeon, Reda Fazazi, Neva Fudge, Irshad Akbar, Asmita Pradeep Yeola, John B. Williams, Mickael Leclercq, Charles Joly-Beauparlant, Philippe Beauchemin, Gian Filipo Ruda, Melanie Alpaugh, Ana C. Anderson, Paul E. Brennan, Arnaud Droit, Hans Lassmann, Craig S. Moore, Manu Rangachari
Published 2021-03-01

Xenobiotic metabolizing gene variants and renal cell cancer: a multicenter study

by Julia E. Heck, Julia E. Heck, Lee eMoore, Yuan-Chin Amy eLee, James eMcKay, Rayjean eHung, Sara eKarami, Valérie eGaborieau, Neonila eSzeszenia-Dabrowska, David eZaridze, Anush eMukeriya, Dana eMates, Lenka eForetova, Vladimir eJanout, Helena eKollárová, Vladimir eBencko, Nathaniel eRothman, Paul eBrennan, Wong-Ho eChow, Paolo eBoffetta
Published 2012-02-01

Sequence variants and the risk of head and neck cancer: pooled analysis in the INHANCE consortium

by Shu-Chun eChuang, Shu-Chun eChuang, Antonio eAgudo, Wolfgang eAhrens, Devasena eAnantharaman, Simone eBenhamou, Stefania eBoccia, Stefania eBoccia, Chu eChen, David eConway, Eleonora eFabianova, Richard B. Hayes, Claire eHealy, Ivana eHolcatova, Kristina eKjaerheim, Pagona eLagiou, Philip eLazarus, Tatiana V. Macfarlane, Manoj eMahimkar, Dana eMates, Keitaro eMatsuo, Franco eMerletti, Andres eMetspalu, Hal eMorgenstern, Joshua eMuscat, Gabriella eCadoni, Andrew F. Olshan, Mark ePurdue, Heribert eRamroth, Péter eRudnai, Stephen M. Schwartz, Lorenzo eSimonato, Elaine M Smith, Erich M. Sturgis, Neonila eSzeszenia-Dabrowska, Renato eTalamini, Peter eThomsom, Qingyi eWei, David eZaridze, Zuo-Feng eZhang, Ariana eZnaor, Paul eBrennan, Paolo eBoffetta, Paolo eBoffetta, Paolo eBoffetta, Mia eHashibe, Mia eHashibe
Published 2011-07-01