Retrospective Identification of Herpes Simplex 2 Virus-Associated Acute Liver Failure in an Immunocompetent Patient Detected Using Whole Transcriptome Shotgun Sequencing

by Atsushi Ono, C. Nelson Hayes, Sakura Akamatsu, Michio Imamura, Hiroshi Aikata, Kazuaki Chayama
Published 2017-01-01

Third-Generation Capsule Endoscopy Outperforms Second-Generation Based on the Detectability of Esophageal Varices

by Sayoko Kunihara, Shiro Oka, Shinji Tanaka, Ichiro Otani, Atsushi Igawa, Yuko Nagaoki, Hiroshi Aikata, Kazuaki Chayama
Published 2016-01-01

Significance of liver resection for intermediate stage hepatocellular carcinoma according to subclassification

by Masateru Yamamoto, Tsuyoshi Kobayashi, Masakazu Hashimoto, Shintaro Kuroda, Tomokazu Kawaoka, Hiroshi Aikata, Kazuaki Chayama, Hideki Ohdan
Published 2021-06-01

The Time Course of Dynamic Computed Tomographic Appearance of Radiation Injury to the Cirrhotic Liver Following Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma.

by Tomoki Kimura, Shigeo Takahashi, Ippei Takahashi, Ikuno Nishibuchi, Yoshiko Doi, Masahiro Kenjo, Yuji Murakami, Yohji Honda, Hiroshi Aikata, Kazuaki Chayama, Yasushi Nagata
Published 2015-01-01

Liver fibrosis assessments using FibroScan, virtual-touch tissue quantification, the FIB-4 index, and mac-2 binding protein glycosylation isomer levels compared with pathological f...

by Naoyuki Ueda, Tomokazu Kawaoka, Michio Imamura, Hiroshi Aikata, Takashi Nakahara, Eisuke Murakami, Masataka Tsuge, Akira Hiramatsu, C. Nelson Hayes, Michiya Yokozaki, Kazuaki Chayama
Published 2020-09-01

Migration to the pulmonary artery of nine metallic coils placed in the internal iliac vein for treatment of giant rectal varices

by Wataru Yamasaki, Hideaki Kakizawa, Masaki Ishikawa, Shuji Date, Fuminari Tatsugami, Hiroaki Terada, Keiichi Masaki, Tomokazu Kawaoka, Masataka Tsuge, Hiroshi Aikata, Kazuaki Chayama, Kazuo Awai
Published 2012-07-01

Rapid, Sensitive, and Accurate Evaluation of Drug Resistant Mutant (NS5A-Y93H) Strain Frequency in Genotype 1b HCV by Invader Assay.

by Satoshi Yoshimi, Hidenori Ochi, Eisuke Murakami, Takuro Uchida, Hiromi Kan, Sakura Akamatsu, C Nelson Hayes, Hiromi Abe, Daiki Miki, Nobuhiko Hiraga, Michio Imamura, Hiroshi Aikata, Kazuaki Chayama
Published 2015-01-01

Pruritus in patients with chronic liver disease and serum autotaxin levels in patients with primary biliary cholangitis

by Hatsue Fujino, Mio Tanaka, Michio Imamura, Kei Morio, Atsushi Ono, Takashi Nakahara, Eisuke Murakami, Tomokazu Kawaoka, Shoichi Takahashi, Daiki Miki, Masataka Tsuge, Akira Hiramatsu, Hiroshi Aikata, C. Nelson Hayes, Kazuaki Chayama
Published 2019-10-01

Hepatitis B virus-specific miRNAs and Argonaute2 play a role in the viral life cycle.

by C Nelson Hayes, Sakura Akamatsu, Masataka Tsuge, Daiki Miki, Rie Akiyama, Hiromi Abe, Hidenori Ochi, Nobuhiko Hiraga, Michio Imamura, Shoichi Takahashi, Hiroshi Aikata, Tomokazu Kawaoka, Yoshiiku Kawakami, Waka Ohishi, Kazuaki Chayama
Published 2012-01-01

Skeletal Muscle Volume Is an Independent Predictor of Survival after Sorafenib Treatment Failure for Hepatocellular Carcinoma

by Issei Saeki, Takahiro Yamasaki, Yurika Yamauchi, Taro Takami, Tomokazu Kawaoka, Shinsuke Uchikawa, Akira Hiramatsu, Hiroshi Aikata, Reo Kawano, Kazufumi Kobayashi, Takayuki Kondo, Sadahisa Ogasawara, Tetsuhiro Chiba, Kazuaki Chayama, Naoya Kato, Isao Sakaida
Published 2021-05-01

Randomized, phase II trial of sequential hepatic arterial infusion chemotherapy and sorafenib versus sorafenib alone as initial therapy for advanced hepatocellular carcinoma: SCOOP...

by Masaaki Kondo, Manabu Morimoto, Satoshi Kobayashi, Shinichi Ohkawa, Hisashi Hidaka, Takahide Nakazawa, Hiroshi Aikata, Takeshi Hatanaka, Daichi Takizawa, Kotaro Matsunaga, Chiaki Okuse, Michihiro Suzuki, Masataka Taguri, Takako Ishibashi, Kazushi Numata, Shin Maeda, Katsuaki Tanaka
Published 2019-10-01

Interferon alpha treatment stimulates interferon gamma expression in type I NKT cells and enhances their antiviral effect against hepatitis C virus.

by Eisuke Miyaki, Nobuhiko Hiraga, Michio Imamura, Takuro Uchida, Hiromi Kan, Masataka Tsuge, Hiromi Abe-Chayama, C Nelson Hayes, Grace Naswa Makokha, Masahiro Serikawa, Hiroshi Aikata, Hidenori Ochi, Yuji Ishida, Chise Tateno, Hideki Ohdan, Kazuaki Chayama
Published 2017-01-01

Identification and monitoring of mutations in circulating cell-free tumor DNA in hepatocellular carcinoma treated with lenvatinib

by Yasutoshi Fujii, Atsushi Ono, C. Nelson Hayes, Hiroshi Aikata, Masami Yamauchi, Shinsuke Uchikawa, Kenichiro Kodama, Yuji Teraoka, Hatsue Fujino, Takashi Nakahara, Eisuke Murakami, Daiki Miki, Wataru Okamoto, Tomokazu Kawaoka, Masataka Tsuge, Michio Imamura, Kazuaki Chayama
Published 2021-06-01

Evaluation of glycemic variability in chronic liver disease patients with type 2 diabetes mellitus using continuous glucose monitoring.

by Fumi Honda, Akira Hiramatsu, Hideyuki Hyogo, Hiroshi Aikata, Kana Daijo, Yuji Teraoka, Yuki Inagaki, Kei Morio, Tomoki Kobayashi, Takashi Nakahara, Yuko Nagaoki, Tomokazu Kawaoka, Masayasu Yoneda, Masataka Tsuge, Michio Imamura, Yoshiiku Kawakami, Hidenori Ochi, Kazuaki Chayama
Published 2018-01-01

A case of acute liver failure with echovirus infection diagnosed by a multi-virus real-time PCR system

by Yuki Yoshikawa, Michio Imamura, Kei Morio, Kenji Yamaoka, Yuwa Ando, Yumi Kosaka, Shinsuke Uchikawa, Hatsue Fujino, Takashi Nakahara, Eisuke Murakami, Masami Yamauchi, Tomokazu Kawaoka, Masataka Tsuge, Akira Hiramatsu, C. Nelson Hayes, Hiroshi Aikata, Takaji Wakita, Harutaka Katano, Kazuaki Chayama
Published 2021-01-01

Classification of primary liver cancer with immunosuppression mechanisms and correlation with genomic alterations

by Masashi Fujita, Rui Yamaguchi, Takanori Hasegawa, Shu Shimada, Koji Arihiro, Shuto Hayashi, Kazuhiro Maejima, Kaoru Nakano, Akihiro Fujimoto, Atsushi Ono, Hiroshi Aikata, Masaki Ueno, Shinya Hayami, Hiroko Tanaka, Satoru Miyano, Hiroki Yamaue, Kazuaki Chayama, Kazuhiro Kakimi, Shinji Tanaka, Seiya Imoto, Hidewaki Nakagawa
Published 2020-03-01

Hepatic Arterial Infusion Chemotherapy versus Sorafenib in Patients with Advanced Hepatocellular Carcinoma

by Kazuomi Ueshima, Sadahisa Ogasawara, Masafumi Ikeda, Yutaka Yasui, Takeshi Terashima, Tatsuya Yamashita, Shuntaro Obi, Shinpei Sato, Hiroshi Aikata, Takumi Ohmura, Hidekatsu Kuroda, Takamasa Ohki, Kengo Nagashima, Yoshihiko Ooka, Masahiro Takita, Masayuki Kurosaki, Kazuaki Chayama, Shuichi Kaneko, Namiki Izumi, Naoya Kato, Masatoshi Kudo, Masao Omata
Published 2020-07-01

Hepatic arterial infusion chemotherapy followed by sorafenib in patients with advanced hepatocellular carcinoma (HICS 55): an open label, non-comparative, phase II trial

by Masahiro Hatooka, Tomokazu Kawaoka, Hiroshi Aikata, Yuki Inagaki, Kei Morio, Takashi Nakahara, Eisuke Murakami, Masataka Tsuge, Akira Hiramatsu, Michio Imamura, Yoshiiku Kawakami, Kazuo Awai, Keiichi Masaki, Koji Waki, Hirotaka Kohno, Hiroshi Kohno, Takashi Moriya, Yuko Nagaoki, Toru Tamura, Hajime Amano, Yoshio Katamura, Kazuaki Chayama
Published 2018-06-01

Increasing incidence of non-HBV- and non-HCV-related hepatocellular carcinoma: single-institution 20-year study

by Yuko Nagaoki, Hideyuki Hyogo, Yuwa Ando, Yumi Kosaka, Shinsuke Uchikawa, Yuno Nishida, Yuji Teraoka, Kei Morio, Hatsue Fujino, Atsushi Ono, Takashi Nakahara, Eisuke Murakami, Masami Yamauchi, Wataru Okamoto, Tomokazu Kawaoka, Masataka Tsuge, Akira Hiramatsu, Daiki Miki, Michio Imamura, Shoichi Takahashi, Kazuaki Chayama, Hiroshi Aikata
Published 2021-07-01

Circulating cytokines and angiogenic factors based signature associated with the relative dose intensity during treatment in patients with advanced hepatocellular carcinoma receivi...

by Atsushi Ono, Hiroshi Aikata, Masami Yamauchi, Kenichiro Kodama, Waka Ohishi, Takeshi Kishi, Kazuki Ohya, Yuji Teraoka, Mitsutaka Osawa, Hatsue Fujino, Takashi Nakahara, Eisuke Murakami, Daiki Miki, Tomokazu Kawaoka, Hiromi Abe-Chayama, Peiyi Zhang, Songyao Liu, Grace Naswa Makokha, Masataka Tsuge, Michio Imamura, C. Nelson Hayes, Kazuaki Chayama
Published 2020-05-01