Protospacer adjacent motif (PAM)-distal sequences engage CRISPR Cas9 DNA target cleavage.

by Regina Cencic, Hisashi Miura, Abba Malina, Francis Robert, Sylvain Ethier, T Martin Schmeing, Josée Dostie, Jerry Pelletier
Published 2014-01-01

Regulation of mammalian 3D genome organization and histone H3K9 dimethylation by H3K9 methyltransferases

by Kei Fukuda, Chikako Shimura, Hisashi Miura, Akie Tanigawa, Takehiro Suzuki, Naoshi Dohmae, Ichiro Hiratani, Yoichi Shinkai
Published 2021-05-01

The Eleanor ncRNAs activate the topological domain of the ESR1 locus to balance against apoptosis

by Mohamed Osama Ali Abdalla, Tatsuro Yamamoto, Kazumitsu Maehara, Jumpei Nogami, Yasuyuki Ohkawa, Hisashi Miura, Rawin Poonperm, Ichiro Hiratani, Hideki Nakayama, Mitsuyoshi Nakao, Noriko Saitoh
Published 2019-08-01

Srf destabilizes cellular identity by suppressing cell-type-specific gene expression programs

by Takashi Ikeda, Takafusa Hikichi, Hisashi Miura, Hirofumi Shibata, Kanae Mitsunaga, Yosuke Yamada, Knut Woltjen, Kei Miyamoto, Ichiro Hiratani, Yasuhiro Yamada, Akitsu Hotta, Takuya Yamamoto, Keisuke Okita, Shinji Masui
Published 2018-04-01