GPR142 Agonists Stimulate Glucose-Dependent Insulin Secretion via Gq-Dependent Signaling.

by Jingru Wang, Juan J Carrillo, Hua V Lin
Published 2016-01-01

InsR/FoxO1 signaling curtails hypothalamic POMC neuron number.

by Leona Plum, Hua V Lin, Kumiko S Aizawa, Yitian Liu, Domenico Accili
Published 2012-01-01

GPR142 Controls Tryptophan-Induced Insulin and Incretin Hormone Secretion to Improve Glucose Metabolism.

by Hua V Lin, Alexander M Efanov, Xiankang Fang, Lisa S Beavers, Xuesong Wang, Jingru Wang, Isabel C Gonzalez Valcarcel, Tianwei Ma
Published 2016-01-01

FOXO1 inhibition synergizes with FGF21 to normalize glucose control in diabetic mice

by Yun-Kyoung Lee, Bryan Diaz, Marianne Deroose, Samuel X. Lee, Sandro Belvedere, Domenico Accili, Rudolph L. Leibel, Hua V. Lin
Published 2021-07-01

GPR142 prompts glucagon-like Peptide-1 release from islets to improve β cell function

by Hua V. Lin, Jingru Wang, Jie Wang, Weiji Li, Xuesong Wang, James T. Alston, Melissa K. Thomas, Daniel A. Briere, Samreen K. Syed, Alexander M. Efanov
Published 2018-05-01

Butyrate and propionate protect against diet-induced obesity and regulate gut hormones via free fatty acid receptor 3-independent mechanisms.

by Hua V Lin, Andrea Frassetto, Edward J Kowalik, Andrea R Nawrocki, Mofei M Lu, Jennifer R Kosinski, James A Hubert, Daphne Szeto, Xiaorui Yao, Gail Forrest, Donald J Marsh
Published 2012-01-01

Identification and characterization of sebaceous gland atrophy-sparing DGAT1 inhibitors.

by Eric S Muise, Yonghua Zhu, Andreas Verras, Bindhu V Karanam, Judith Gorski, Drew Weingarth, Hua V Lin, Joyce Hwa, John R Thompson, Guanghui Hu, Jian Liu, Shuwen He, Robert J DeVita, Dong-Ming Shen, Shirly Pinto
Published 2014-01-01

Diacylglycerol acyltransferase-1 (DGAT1) inhibition perturbs postprandial gut hormone release.

by Hua V Lin, Dunlu Chen, Zhu Shen, Lei Zhu, Xuesong Ouyang, Aurawan Vongs, Yanqing Kan, John M Levorse, Edward J Kowalik, Daphne M Szeto, Xiaorui Yao, Jianying Xiao, Shirley Chen, Jinqi Liu, Marga Garcia-Calvo, Myung K Shin, Shirly Pinto
Published 2013-01-01