Development and validation of a quantitative, high-throughput, fluorescent-based bioassay to detect schistosoma viability.

by Emily Peak, Iain W Chalmers, Karl F Hoffmann
Published 2010-07-01

Identification of 6-(piperazin-1-yl)-1,3,5-triazine as a chemical scaffold with broad anti-schistosomal activities [version 1; peer review: 1 approved, 2 approved with reservations...

by Gilda Padalino, Iain W. Chalmers, Andrea Brancale, Karl F. Hoffmann
Published 2020-07-01

Identification of 6-(piperazin-1-yl)-1,3,5-triazine as a chemical scaffold with broad anti-schistosomal activities [version 2; peer review: 1 approved, 2 approved with reservations...

by Gilda Padalino, Iain W. Chalmers, Andrea Brancale, Karl F. Hoffmann
Published 2020-11-01

Combining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma mansoni

by Gilda Padalino, Salvatore Ferla, Andrea Brancale, Iain W. Chalmers, Karl F. Hoffmann
Published 2018-12-01

Anti-schistosomal intervention targets identified by lifecycle transcriptomic analyses.

by Jennifer M Fitzpatrick, Emily Peak, Samirah Perally, Iain W Chalmers, John Barrett, Timothy P Yoshino, Alasdair C Ivens, Karl F Hoffmann
Published 2009-11-01

The plain language Glossary of Evaluation Terms for Informed Treatment choices (GET-IT) at www.getitglossary.org

by Jenny Moberg, Astrid Austvoll-Dahlgren, Shaun Treweek, Douglas Badenoch, Robin Layfield, Robin Harbour, Sarah Rosenbaum, Andrew D Oxman, Patricia Atkinson, Iain W. Chalmers
Published 2018-01-01

The Schistosoma mansoni tegumental-allergen-like (TAL) protein family: influence of developmental expression on human IgE responses.

by Colin M Fitzsimmons, Frances M Jones, Alex Stearn, Iain W Chalmers, Karl F Hoffmann, Jakub Wawrzyniak, Shona Wilson, Narcis B Kabatereine, David W Dunne
Published 2012-01-01

The repositioning of epigenetic probes/inhibitors identifies new anti-schistosomal lead compounds and chemotherapeutic targets.

by Kezia C L Whatley, Gilda Padalino, Helen Whiteland, Kathrin K Geyer, Benjamin J Hulme, Iain W Chalmers, Josephine Forde-Thomas, Salvatore Ferla, Andrea Brancale, Karl F Hoffmann
Published 2019-11-01

Human IgG1 Responses to Surface Localised Schistosoma mansoni Ly6 Family Members Drop following Praziquantel Treatment.

by Iain W Chalmers, Colin M Fitzsimmons, Martha Brown, Christine Pierrot, Frances M Jones, Jakub M Wawrzyniak, Narcis Fernandez-Fuentes, Edridah M Tukahebwa, David W Dunne, Jamal Khalife, Karl F Hoffmann
Published 2015-01-01

Drug-induced exposure of Schistosoma mansoni antigens SmCD59a and SmKK7.

by Natalie Reimers, Arne Homann, Beate Höschler, Kristina Langhans, R Alan Wilson, Christine Pierrot, Jamal Khalife, Christoph G Grevelding, Iain W Chalmers, Maria Yazdanbakhsh, Karl F Hoffmann, Cornelis H Hokke, Helmut Haas, Gabriele Schramm
Published 2015-03-01

The Biomphalaria glabrata DNA methylation machinery displays spatial tissue expression, is differentially active in distinct snail populations and is modulated by interactions with...

by Kathrin K Geyer, Umar H Niazi, David Duval, Céline Cosseau, Chad Tomlinson, Iain W Chalmers, Martin T Swain, David J Cutress, Utibe Bickham-Wright, Sabrina E Munshi, Christoph Grunau, Timothy P Yoshino, Karl F Hoffmann
Published 2017-05-01

Correction: Corrigendum: Whole genome analysis of a schistosomiasis-transmitting freshwater snail

by Coen M. Adema, LaDeana W. Hillier, Catherine S. Jones, Eric S. Loker, Matty Knight, Patrick Minx, Guilherme Oliveira, Nithya Raghavan, Andrew Shedlock, Laurence Rodrigues do Amaral, Halime D. Arican-Goktas, Juliana G. Assis, Elio Hideo Baba, Olga L. Baron, Christopher J. Bayne, Utibe Bickham-Wright, Kyle K. Biggar, Michael Blouin, Bryony C. Bonning, Chris Botka, Joanna M. Bridger, Katherine M. Buckley, Sarah K. Buddenborg, Roberta Lima Caldeira, Julia Carleton, Omar S. Carvalho, Maria G. Castillo, Iain W. Chalmers, Mikkel Christensens, Sandra Clifton, Celine Cosseau, Christine Coustau, Richard M. Cripps, Yesid Cuesta-Astroz, Scott F. Cummins, Leon Di Stefano, Nathalie Dinguirard, David Duval, Scott Emrich, Cédric Feschotte, Rene Feyereisen, Peter FitzGerald, Catrina Fronick, Lucinda Fulton, Richard Galinier, Sandra G. Gava, Michael Geusz, Kathrin K. Geyer, Gloria I. Giraldo-Calderón, Matheus de Souza Gomes, Michelle A. Gordy, Benjamin Gourbal, Christoph Grunau, Patrick C. Hanington, Karl F. Hoffmann, Daniel Hughes, Judith Humphries, Daniel J. Jackson, Liana K. Jannotti-Passos, Wander de Jesus Jeremias, Susan Jobling, Bishoy Kamel, Aurélie Kapusta, Satwant Kaur, Joris M. Koene, Andrea B. Kohn, Dan Lawson, Scott P. Lawton, Di Liang, Yanin Limpanont, Sijun Liu, Anne E. Lockyer, Ty Anna L. Lovato, Fernanda Ludolf, Vince Magrini, Donald P. McManus, Monica Medina, Milind Misra, Guillaume Mitta, Gerald M. Mkoji, Michael J. Montague, Cesar Montelongo, Leonid L. Moroz, Monica C. Munoz-Torres, Umar Niazi, Leslie R. Noble, Francislon S. Oliveira, Fabiano S. Pais, Anthony T. Papenfuss, Rob Peace, Janeth J. Pena, Emmanuel A. Pila, Titouan Quelais, Brian J. Raney, Jonathan P. Rast, David Rollinson, Izinara C. Rosse, Bronwyn Rotgans, Edwin J. Routledge, Kathryn M. Ryan, Larissa L. S. Scholte, Kenneth B. Storey, Martin Swain, Jacob A. Tennessen, Chad Tomlinson, Damian L. Trujillo, Emanuela V. Volpi, Anthony J. Walker, Tianfang Wang, Ittiprasert Wannaporn, Wesley C. Warren, Xiao-Jun Wu, Timothy P. Yoshino, Mohammed Yusuf, Si-Ming Zhang, Min Zhao, Richard K. Wilson
Published 2017-08-01

Whole genome analysis of a schistosomiasis-transmitting freshwater snail

by Coen M. Adema, LaDeana W. Hillier, Catherine S. Jones, Eric S. Loker, Matty Knight, Patrick Minx, Guilherme Oliveira, Nithya Raghavan, Andrew Shedlock, Laurence Rodrigues do Amaral, Halime D. Arican-Goktas, Juliana G. Assis, Elio Hideo Baba, Olga L. Baron, Christopher J. Bayne, Utibe Bickham-Wright, Kyle K. Biggar, Michael Blouin, Bryony C. Bonning, Chris Botka, Joanna M. Bridger, Katherine M. Buckley, Sarah K. Buddenborg, Roberta Lima Caldeira, Julia Carleton, Omar S. Carvalho, Maria G. Castillo, Iain W. Chalmers, Mikkel Christensens, Sandra Clifton, Celine Cosseau, Christine Coustau, Richard M. Cripps, Yesid Cuesta-Astroz, Scott F. Cummins, Leon di Stefano, Nathalie Dinguirard, David Duval, Scott Emrich, Cédric Feschotte, Rene Feyereisen, Peter FitzGerald, Catrina Fronick, Lucinda Fulton, Richard Galinier, Sandra G. Gava, Michael Geusz, Kathrin K. Geyer, Gloria I. Giraldo-Calderón, Matheus de Souza Gomes, Michelle A. Gordy, Benjamin Gourbal, Christoph Grunau, Patrick C. Hanington, Karl F. Hoffmann, Daniel Hughes, Judith Humphries, Daniel J. Jackson, Liana K. Jannotti-Passos, Wander de Jesus Jeremias, Susan Jobling, Bishoy Kamel, Aurélie Kapusta, Satwant Kaur, Joris M. Koene, Andrea B. Kohn, Dan Lawson, Scott P Lawton, Di Liang, Yanin Limpanont, Sijun Liu, Anne E. Lockyer, TyAnna L. Lovato, Fernanda Ludolf, Vince Magrini, Donald P. McManus, Monica Medina, Milind Misra, Guillaume Mitta, Gerald M. Mkoji, Michael J. Montague, Cesar Montelongo, Leonid L. Moroz, Monica C. Munoz-Torres, Umar Niazi, Leslie R. Noble, Francislon S. Oliveira, Fabiano S. Pais, Anthony T. Papenfuss, Rob Peace, Janeth J. Pena, Emmanuel A. Pila, Titouan Quelais, Brian J. Raney, Jonathan P. Rast, David Rollinson, Izinara C. Rosse, Bronwyn Rotgans, Edwin J. Routledge, Kathryn M. Ryan, Larissa L. S. Scholte, Kenneth B. Storey, Martin Swain, Jacob A. Tennessen, Chad Tomlinson, Damian L. Trujillo, Emanuela V. Volpi, Anthony J. Walker, Tianfang Wang, Ittiprasert Wannaporn, Wesley C. Warren, Xiao-Jun Wu, Timothy P. Yoshino, Mohammed Yusuf, Si-Ming Zhang, Min Zhao, Richard K. Wilson
Published 2017-05-01