Cancer as a System Failure

by Dennis Wigle, Igor Jurisica
Published 2007-01-01

Cancer as a System Failure

by Igor Jurisica, Dennis Wigle
Published 2007-01-01

In silico cancer research towards 3R

by Claire Jean-Quartier, Fleur Jeanquartier, Igor Jurisica, Andreas Holzinger
Published 2018-04-01

NAViGaTing the micronome--using multiple microRNA prediction databases to identify signalling pathway-associated microRNAs.

by Elize A Shirdel, Wing Xie, Tak W Mak, Igor Jurisica
Published 2011-02-01

Visual data mining of biological networks: one size does not fit all.

by Chiara Pastrello, David Otasek, Kristen Fortney, Giuseppe Agapito, Mario Cannataro, Elize Shirdel, Igor Jurisica
Published 2013-01-01

Prioritizing therapeutics for lung cancer: an integrative meta-analysis of cancer gene signatures and chemogenomic data.

by Kristen Fortney, Joshua Griesman, Max Kotlyar, Chiara Pastrello, Marc Angeli, Ming Sound-Tsao, Igor Jurisica
Published 2015-03-01

The Murine Caecal MicroRNA Signature Depends on the Presence of the Endogenous Microbiota

by Natasha Singh, Elize A. Shirdel, Levi Waldron, Regan-Heng Zhang, Igor Jurisica, Elena M. Comelli
Published 2012-01-01

Tumor cell endogenous HIF-1α activity induces aberrant angiogenesis and interacts with TRAF6 pathway required for colorectal cancer development

by Jesus F. Glaus Garzon, Chiara Pastrello, Igor Jurisica, Michael O. Hottiger, Roland H. Wenger, Lubor Borsig
Published 2020-12-01

Position- and Hippo signaling-dependent plasticity during lineage segregation in the early mouse embryo

by Eszter Posfai, Sophie Petropoulos, Flavia Regina Oliveira de Barros, John Paul Schell, Igor Jurisica, Rickard Sandberg, Fredrik Lanner, Janet Rossant
Published 2017-02-01

Stability and Heterogeneity of Expression Profiles in Lung Cancer Specimens Harvested Following Surgical Resection

by Fiona H. Blackhall, Melania Pintilie, Dennis A. Wigle, Igor Jurisica, Ni Liu, Nikolina Radulovich, Michael R. Johnston, Shaf Keshavjee, Ming-Sound Tsao
Published 2004-11-01

Split Intein-Mediated Protein Ligation for detecting protein-protein interactions and their inhibition

by Zhong Yao, Farzaneh Aboualizadeh, Jason Kroll, Indira Akula, Jamie Snider, Anna Lyakisheva, Priscilla Tang, Max Kotlyar, Igor Jurisica, Mike Boxem, Igor Stagljar
Published 2020-05-01

Rho-GTPase pathways may differentiate treatment response to TNF-alpha and IL-17A inhibitors in psoriatic arthritis

by Sara Rahmati, Darren D. O’Rielly, Quan Li, Dianne Codner, Amanda Dohey, Kari Jenkins, Igor Jurisica, Dafna D. Gladman, Vinod Chandran, Proton Rahman
Published 2020-12-01

Immune-enrichment of non-small cell lung cancer baseline biopsies for multiplex profiling define prognostic immune checkpoint combinations for patient stratification

by Anne Monette, Derek Bergeron, Amira Ben Amor, Liliane Meunier, Christine Caron, Anne-Marie Mes-Masson, Nidhameddine Kchir, Kamel Hamzaoui, Igor Jurisica, Réjean Lapointe
Published 2019-03-01

Effect of autotaxin inhibition in a surgically-induced mouse model of osteoarthritis

by Poulami Datta, Rajiv Gandhi, Sayaka Nakamura, Starlee Lively, Evgeny Rossomacha, Pratibha Potla, Konstantin Shestopaloff, Helal Endisha, Chiara Pastrello, Igor Jurisica, Jason S. Rockel, Mohit Kapoor
Published 2020-09-01

An integrative genomic and transcriptomic analysis reveals potential targets associated with cell proliferation in uterine leiomyomas.

by Priscila Daniele Ramos Cirilo, Fábio Albuquerque Marchi, Mateus de Camargo Barros Filho, Rafael Malagoli Rocha, Maria Aparecida Custódio Domingues, Igor Jurisica, Anagloria Pontes, Silvia Regina Rogatto
Published 2013-01-01

Automated microinjection of recombinant BCL-X into mouse zygotes enhances embryo development.

by Xinyu Liu, Roxanne Fernandes, Marina Gertsenstein, Alagammal Perumalsamy, Ingrid Lai, Maggie Chi, Kelle H Moley, Ellen Greenblatt, Igor Jurisica, Robert F Casper, Yu Sun, Andrea Jurisicova
Published 2011-01-01

Urinary proteomics links keratan sulfate degradation and lysosomal enzymes to early type 1 diabetes.

by Julie A D Van, Sergi Clotet-Freixas, Anne-Christin Hauschild, Ihor Batruch, Igor Jurisica, Yesmino Elia, Farid H Mahmud, Etienne Sochett, Eleftherios P Diamandis, James W Scholey, Ana Konvalinka
Published 2020-01-01

Large-scale discovery of previously undetected microRNAs specific to human liver

by Brenda C. Minatel, Victor D. Martinez, Kevin W. Ng, Adam P. Sage, Tomas Tokar, Erin A. Marshall, Christine Anderson, Katey S. S. Enfield, Greg L. Stewart, Patricia P. Reis, Igor Jurisica, Wan L. Lam
Published 2018-03-01

Reactivation of Multiple Fetal miRNAs in Lung Adenocarcinoma

by David E. Cohn, Mateus C. Barros-Filho, Brenda C. Minatel, Michelle E. Pewarchuk, Erin A. Marshall, Emily A. Vucic, Adam P. Sage, Nikita Telkar, Greg L. Stewart, Igor Jurisica, Patricia P. Reis, Wendy P. Robinson, Wan L. Lam
Published 2021-05-01

Epithelial tumor suppressor ELF3 is a lineage-specific amplified oncogene in lung adenocarcinoma

by Katey S. S. Enfield, Erin A. Marshall, Christine Anderson, Kevin W. Ng, Sara Rahmati, Zhaolin Xu, Megan Fuller, Katy Milne, Daniel Lu, Rocky Shi, David A. Rowbotham, Daiana D. Becker-Santos, Fraser D. Johnson, John C. English, Calum E. MacAulay, Stephen Lam, William W. Lockwood, Raj Chari, Aly Karsan, Igor Jurisica, Wan L. Lam
Published 2019-11-01