Distinct contributions of Orai1 and TRPC1 to agonist-induced [Ca(2+)](i) signals determine specificity of Ca(2+)-dependent gene expression.

by Hwei Ling Ong, Shyh-Ing Jang, Indu Suresh Ambudkar
Published 2012-01-01

Local Ca²+ entry via Orai1 regulates plasma membrane recruitment of TRPC1 and controls cytosolic Ca²+ signals required for specific cell functions.

by Kwong Tai Cheng, Xibao Liu, Hwei Ling Ong, William Swaim, Indu S Ambudkar
Published 2011-03-01

STIM2 Induces Activated Conformation of STIM1 to Control Orai1 Function in ER-PM Junctions

by Krishna Prasad Subedi, Hwei Ling Ong, Ga-Yeon Son, Xibao Liu, Indu Suresh Ambudkar
Published 2018-04-01

TRIC-A shapes oscillatory Ca2+ signals by interaction with STIM1/Orai1 complexes.

by Niroj Shrestha, Bernadett Bacsa, Hwei Ling Ong, Susanne Scheruebel, Helmut Bischof, Roland Malli, Indu Suresh Ambudkar, Klaus Groschner
Published 2020-04-01

Matriptase deletion initiates a Sjögren's syndrome-like disease in mice.

by Hongen Yin, Peter Kosa, Xibao Liu, William D Swaim, Zhennan Lai, Javier Cabrera-Perez, Giovanni Di Pasquale, Indu S Ambudkar, Thomas H Bugge, John A Chiorini
Published 2014-01-01

Store-operated Ca2+ entry is remodelled and controls in vitro angiogenesis in endothelial progenitor cells isolated from tumoral patients.

by Francesco Lodola, Umberto Laforenza, Elisa Bonetti, Dmitry Lim, Silvia Dragoni, Cinzia Bottino, Hwei Ling Ong, Germano Guerra, Carlo Ganini, Margherita Massa, Mariangela Manzoni, Indu S Ambudkar, Armando A Genazzani, Vittorio Rosti, Paolo Pedrazzoli, Franco Tanzi, Francesco Moccia, Camillo Porta
Published 2012-01-01