A Common Origin for B-1a and B-2 Lymphocytes in Clonal Pre- Hematopoietic Stem Cells

by Brandon K. Hadland, Barbara Varnum-Finney, Pankaj K. Mandal, Derrick J. Rossi, Michael G. Poulos, Jason M. Butler, Shahin Rafii, Mervin C. Yoder, Momoko Yoshimoto, Irwin D. Bernstein
Published 2017-06-01

Engineered Murine HSCs Reconstitute Multi-lineage Hematopoiesis and Adaptive Immunity

by Yi-Fen Lu, Patrick Cahan, Samantha Ross, Julie Sahalie, Patricia M. Sousa, Brandon K. Hadland, Wenqing Cai, Erik Serrao, Alan N. Engelman, Irwin D. Bernstein, George Q. Daley
Published 2016-12-01

Multipotent progenitors and hematopoietic stem cells arise independently from hemogenic endothelium in the mouse embryo

by Tessa Dignum, Barbara Varnum-Finney, Sanjay R. Srivatsan, Stacey Dozono, Olivia Waltner, Adam M. Heck, Takashi Ishida, Cynthia Nourigat-McKay, Dana L. Jackson, Shahin Rafii, Cole Trapnell, Irwin D. Bernstein, Brandon Hadland
Published 2021-09-01

NOTCH signaling specifies arterial-type definitive hemogenic endothelium from human pluripotent stem cells

by Gene I. Uenishi, Ho Sun Jung, Akhilesh Kumar, Mi Ae Park, Brandon K. Hadland, Ethan McLeod, Matthew Raymond, Oleg Moskvin, Catherine E. Zimmerman, Derek J. Theisen, Scott Swanson, Owen J. Tamplin, Leonard I. Zon, James A. Thomson, Irwin D. Bernstein, Igor I. Slukvin
Published 2018-05-01

Angiopoietin-like proteins stimulate HSPC development through interaction with notch receptor signaling

by Michelle I Lin, Emily N Price, Sonja Boatman, Elliott J Hagedorn, Eirini Trompouki, Sruthi Satishchandran, Charles W Carspecken, Audrey Uong, Anthony DiBiase, Song Yang, Matthew C Canver, Ann Dahlberg, Zhigang Lu, Cheng Cheng Zhang, Stuart H Orkin, Irwin D Bernstein, Jon C Aster, Richard M White, Leonard I Zon
Published 2015-02-01