Self and non-self discrimination of intracellular membranes by the innate immune system.

by Jörn Coers
Published 2013-09-01

Modeling infectious disease in mice: co-adaptation and the role of host-specific IFNgamma responses.

by Jörn Coers, Michael N Starnbach, Jonathan C Howard
Published 2009-05-01

Guanylate Binding Proteins Restrict Leishmania donovani Growth in Nonphagocytic Cells Independent of Parasitophorous Vacuolar Targeting

by Arun Kumar Haldar, Utsav Nigam, Masahiro Yamamoto, Jörn Coers, Neena Goyal
Published 2020-07-01

The E2-like conjugation enzyme Atg3 promotes binding of IRG and Gbp proteins to Chlamydia- and Toxoplasma-containing vacuoles and host resistance.

by Arun K Haldar, Anthony S Piro, Danielle M Pilla, Masahiro Yamamoto, Jörn Coers
Published 2014-01-01

A Rapidly Evolving Polybasic Motif Modulates Bacterial Detection by Guanylate Binding Proteins

by Kristin M. Kohler, Miriam Kutsch, Anthony S. Piro, Graham D. Wallace, Jörn Coers, Matthew F. Barber
Published 2020-05-01

Compensatory T cell responses in IRG-deficient mice prevent sustained Chlamydia trachomatis infections.

by Jörn Coers, Dave C Gondek, Andrew J Olive, Amy Rohlfing, Gregory A Taylor, Michael N Starnbach
Published 2011-06-01

C57BL/6 and 129 inbred mouse strains differ in Gbp2 and Gbp2b expression in response to inflammatory stimuli in vivo [version 1; peer review: 2 approved]

by Barbara Clough, Ryan Finethy, Rabia T. Khan, Daniel Fisch, Sarah Jordan, Harshil Patel, Jörn Coers, Eva-Maria Frickel
Published 2019-08-01

Constitutive Interferon Maintains GBP Expression Required for Release of Bacterial Components Upstream of Pyroptosis and Anti-DNA Responses

by Beiyun C. Liu, Joseph Sarhan, Alexander Panda, Hayley I. Muendlein, Vladimir Ilyukha, Jörn Coers, Masahiro Yamamoto, Ralph R. Isberg, Alexander Poltorak
Published 2018-07-01

IRG1 and Inducible Nitric Oxide Synthase Act Redundantly with Other Interferon-Gamma-Induced Factors To Restrict Intracellular Replication of Legionella pneumophila

by Jordan V. Price, Daniel Russo, Daisy X. Ji, Roberto A. Chavez, Lucian DiPeso, Angus Yiu-Fai Lee, Jörn Coers, Russell E. Vance
Published 2019-11-01

Detection of Cytosolic Shigella flexneri via a C-Terminal Triple-Arginine Motif of GBP1 Inhibits Actin-Based Motility

by Anthony S. Piro, Dulcemaria Hernandez, Sarah Luoma, Eric M. Feeley, Ryan Finethy, Azeb Yirga, Eva M. Frickel, Cammie F. Lesser, Jorn Coers, Russell Vance
Published 2017-12-01

Chlamydia trachomatis Is Resistant to Inclusion Ubiquitination and Associated Host Defense in Gamma Interferon-Primed Human Epithelial Cells

by Arun K. Haldar, Anthony S. Piro, Ryan Finethy, Scott T. Espenschied, Hannah E. Brown, Amanda M. Giebel, Eva-Maria Frickel, David E. Nelson, Jorn Coers
Published 2016-12-01

IRG and GBP host resistance factors target aberrant, "non-self" vacuoles characterized by the missing of "self" IRGM proteins.

by Arun K Haldar, Hector A Saka, Anthony S Piro, Joe Dan Dunn, Stanley C Henry, Gregory A Taylor, Eva M Frickel, Raphael H Valdivia, Jörn Coers
Published 2013-01-01

Inflammasome Activation by Bacterial Outer Membrane Vesicles Requires Guanylate Binding Proteins

by Ryan Finethy, Sarah Luoma, Nichole Orench-Rivera, Eric M. Feeley, Arun K. Haldar, Masahiro Yamamoto, Thirumala-Devi Kanneganti, Meta J. Kuehn, Jorn Coers, David S. Weiss, Eric J. Rubin
Published 2017-10-01

The Listeria monocytogenes PASTA Kinase PrkA and Its Substrate YvcK Are Required for Cell Wall Homeostasis, Metabolism, and Virulence.

by Daniel A Pensinger, Kyle M Boldon, Grischa Y Chen, William J B Vincent, Kyle Sherman, Meng Xiong, Adam J Schaenzer, Emily R Forster, Jörn Coers, Rob Striker, John-Demian Sauer
Published 2016-11-01

Genetic Screen in Chlamydia muridarum Reveals Role for an Interferon-Induced Host Cell Death Program in Antimicrobial Inclusion Rupture

by Amanda M. Giebel, Shuai Hu, Krithika Rajaram, Ryan Finethy, Evelyn Toh, Julie A. Brothwell, Sandra G. Morrison, Robert J. Suchland, Barry D. Stein, Jörn Coers, Richard P. Morrison, David E. Nelson
Published 2019-04-01

Search for microRNAs expressed by intracellular bacterial pathogens in infected mammalian cells.

by Yuki Furuse, Ryan Finethy, Hector A Saka, Ana M Xet-Mull, Dana M Sisk, Kristen L Jurcic Smith, Sunhee Lee, Jörn Coers, Raphael H Valdivia, David M Tobin, Bryan R Cullen
Published 2014-01-01