The future of faecal microbiota transplantation in gastrointestinal illness

by Jakob Begun, Hayley Reed
Published 2020-01-01

Malnutrition and quality of life among adult inflammatory bowel disease patients

by Jessica Pulley, Alwyn Todd, Christopher Flatley, Jakob Begun
Published 2020-06-01

Enterococcus faecalis AHG0090 is a Genetically Tractable Bacterium and Produces a Secreted Peptidic Bioactive that Suppresses Nuclear Factor Kappa B Activation in Human Gut Epithel...

by Páraic Ó Cuív, Rabina Giri, Emily C. Hoedt, Michael A. McGuckin, Jakob Begun, Mark Morrison
Published 2018-04-01

Staphylococcal biofilm exopolysaccharide protects against Caenorhabditis elegans immune defenses.

by Jakob Begun, Jessica M Gaiani, Holger Rohde, Dietrich Mack, Stephen B Calderwood, Frederick M Ausubel, Costi D Sifri
Published 2007-04-01

IgM and IgA augmented autoantibody signatures improve early‐stage detection of colorectal cancer prior to nodal and distant spread

by Md Saiful Islam Roney, Catharine Lanagan, Yong Hua Sheng, Karen Lawler, Christopher Schmidt, Nam‐Trung Nguyen, Jakob Begun, Gregor Stefan Kijanka
Published 2021-01-01

Gastrointestinal ultrasound in inflammatory bowel disease care: Patient perceptions and impact on disease‐related knowledge

by Arvind Rajagopalan, Dharshan Sathananthan, Yoon‐Kyo An, Lucinda Van De Ven, Serena Martin, James Fon, Samuel P Costello, Jakob Begun, Robert V Bryant
Published 2020-04-01

Expression of CD49f defines subsets of human regulatory T cells with divergent transcriptional landscape and function that correlate with ulcerative colitis disease activity

by Harshi Weerakoon, Jasmin Straube, Katie Lineburg, Leanne Cooper, Steven Lane, Corey Smith, Saleh Alabbas, Jakob Begun, John J Miles, Michelle M Hill, Ailin Lepletier
Published 2021-01-01

Gut microbiota shape the inflammatory response in mice with an epithelial defect

by Ran Wang, Md Moniruzzaman, Kuan Yau Wong, Percival Wiid, Alexa Harding, Rabina Giri, Wendy (Hui) Tong, Jackie Creagh, Jakob Begun, Michael A. McGuckin, Sumaira Z. Hasnain
Published 2021-01-01

A Nucleotide Analog Prevents Colitis-Associated Cancer via Beta-Catenin Independently of Inflammation and AutophagySummary

by Yong Hua Sheng, Rabina Giri, Julie Davies, Veronika Schreiber, Saleh Alabbas, Ramya Movva, Yaowu He, Andy Wu, John Hooper, Brett McWhinney, Iulia Oancea, Gregor Kijanka, Sumaira Hasnain, Andrew J. Lucke, David P. Fairlie, Michael A. McGuckin, Timothy H. Florin, Jakob Begun
Published 2021-01-01

Prospective randomised controlled trial of adults with perianal fistulising Crohn’s disease and optimised therapeutic infliximab levels: PROACTIVE trial study protocol

by Danny Liew, Ailsa Hart, Niels Vande Casteele, Jordi Rimola, Jane M Andrews, Jakob Begun, Yang Wu, Wei Xuan, Nik Sheng Ding, Bonita Gu, Michael De Gregorio, Joseph Louis Pipicella, William Connell, Basil D’Souza, Ali Gholamrezaei, Graham Radford-Smith, Tom Sutherland, Catherine Toong, Rodney Woods, Watson Ng
Published 2021-07-01

Integrated Genomics of Crohn’s Disease Risk Variant Identifies a Role for CLEC12A in Antibacterial Autophagy

by Jakob Begun, Kara G. Lassen, Humberto B. Jijon, Leigh A. Baxt, Gautam Goel, Robert J. Heath, Aylwin Ng, Jenny M. Tam, Szu-Yu Kuo, Eduardo J. Villablanca, Lola Fagbami, Marije Oosting, Vinod Kumar, Monica Schenone, Steven A. Carr, Leo A.B. Joosten, Jatin M. Vyas, Mark J. Daly, Mihai G. Netea, Gordon D. Brown, Cisca Wijmenga, Ramnik J. Xavier
Published 2015-06-01

Deep resequencing of GWAS loci identifies rare variants in CARD9, IL23R and RNF186 that are associated with ulcerative colitis.

by Mélissa Beaudoin, Philippe Goyette, Gabrielle Boucher, Ken Sin Lo, Manuel A Rivas, Christine Stevens, Azadeh Alikashani, Martin Ladouceur, David Ellinghaus, Leif Törkvist, Gautam Goel, Caroline Lagacé, Vito Annese, Alain Bitton, Jakob Begun, Steve R Brant, Francesca Bresso, Judy H Cho, Richard H Duerr, Jonas Halfvarson, Dermot P B McGovern, Graham Radford-Smith, Stefan Schreiber, Philip L Schumm, Yashoda Sharma, Mark S Silverberg, Rinse K Weersma, Quebec IBD Genetics Consortium, NIDDK IBD Genetics Consortium, International IBD Genetics Consortium, Mauro D'Amato, Severine Vermeire, Andre Franke, Guillaume Lettre, Ramnik J Xavier, Mark J Daly, John D Rioux
Published 2013-01-01