Serine protease(s) secreted by the nematode Trichuris muris degrade the mucus barrier.

by Sumaira Z Hasnain, Michael A McGuckin, Richard K Grencis, David J Thornton
Published 2012-01-01

Interleukin (IL)-22 from IL-20 Subfamily of Cytokines Induces Colonic Epithelial Cell Proliferation Predominantly through ERK1/2 Pathway

by Md. Moniruzzaman, Ran Wang, Varinder Jeet, Michael A. McGuckin, Sumaira Z. Hasnain
Published 2019-07-01

Pre-Diabetes Increases Tuberculosis Disease Severity, While High Body Fat Without Impaired Glucose Tolerance Is Protective

by Roma Sinha, Minh Dao Ngo, Stacey Bartlett, Helle Bielefeldt-Ohmann, Helle Bielefeldt-Ohmann, Sahar Keshvari, Sumaira Z. Hasnain, Sumaira Z. Hasnain, Meg L. Donovan, Jessica C. Kling, Antje Blumenthal, Antje Blumenthal, Chen Chen, Kirsty R. Short, Kirsty R. Short, Katharina Ronacher, Katharina Ronacher
Published 2021-07-01

Immune-driven alterations in mucin sulphation is an important mediator of Trichuris muris helminth expulsion.

by Sumaira Z Hasnain, Paul A Dawson, Rohan Lourie, Peter Hutson, Hui Tong, Richard K Grencis, Michael A McGuckin, David J Thornton
Published 2017-02-01

Fibre Intake Is Independently Associated with Increased Circulating Interleukin-22 in Individuals with Metabolic Syndrome

by Luciana Torquati, Jeff S. Coombes, Lydia Murray, Sumaira Z. Hasnain, Alistair R. Mallard, Michael A. McGuckin, Robert G. Fassett, Ilaria Croci, Joyce S. Ramos
Published 2019-04-01

Rationally Designed Dendritic Silica Nanoparticles for Oral Delivery of Exenatide

by Muhammad Mustafa Abeer, Anand Kumar Meka, Naisarg Pujara, Tushar Kumeria, Ekaterina Strounina, Rute Nunes, Ana Costa, Bruno Sarmento, Sumaira Z. Hasnain, Benjamin P. Ross, Amirali Popat
Published 2019-08-01

Gut microbiota shape the inflammatory response in mice with an epithelial defect

by Ran Wang, Md Moniruzzaman, Kuan Yau Wong, Percival Wiid, Alexa Harding, Rabina Giri, Wendy (Hui) Tong, Jackie Creagh, Jakob Begun, Michael A. McGuckin, Sumaira Z. Hasnain
Published 2021-01-01

Adult non-cystic fibrosis bronchiectasis is characterised by airway luminal Th17 pathway activation.

by Alice C-H Chen, Megan L Martin, Rohan Lourie, Geraint B Rogers, Lucy D Burr, Sumaira Z Hasnain, Simon D Bowler, Michael A McGuckin, David J Serisier
Published 2015-01-01

PPARγ is reduced in the airways of non-CF bronchiectasis subjects and is inversely correlated with the presence of Pseudomonas aeruginosa.

by Lucy D Burr, Geraint B Rogers, Alice C-H Chen, Steven L Taylor, Simon D Bowler, Rebecca L Keating, Megan L Martin, Sumaira Z Hasnain, Michael A McGuckin
Published 2018-01-01

Influence of the MUC1 Cell Surface Mucin on Gastric Mucosal Gene Expression Profiles in Response to Helicobacter pylori Infection in Mice

by Yong H. Sheng, Garrett Z. Ng, Kim M. Summers, Alison L. Every, Gareth Price, Sumaira Z. Hasnain, Philip Sutton, Philip Sutton, Michael A. McGuckin, Michael A. McGuckin
Published 2020-07-01

High glucose levels increase influenza-associated damage to the pulmonary epithelial-endothelial barrier

by Katina D Hulme, Limin Yan, Rebecca J Marshall, Conor J Bloxham, Kyle R Upton, Sumaira Z Hasnain, Helle Bielefeldt-Ohmann, Zhixuan Loh, Katharina Ronacher, Keng Yih Chew, Linda A Gallo, Kirsty R Short
Published 2020-07-01