Post translational changes to α-synuclein control iron and dopamine trafficking; a concept for neuron vulnerability in Parkinson’s disease

by James A. Duce, Bruce X. Wong, Hannah Durham, Jean-Christophe Devedjian, David P. Smith, David Devos
Published 2017-06-01

β-Amyloid precursor protein does not possess ferroxidase activity but does stabilize the cell surface ferrous iron exporter ferroportin.

by Bruce X Wong, Andrew Tsatsanis, Linh Q Lim, Paul A Adlard, Ashley I Bush, James A Duce
Published 2014-01-01

Recapitulating Parkinson's disease pathology in a three-dimensional human neural cell culture model

by Teresa R. Taylor-Whiteley, Christine L. Le Maitre, James A. Duce, Caroline F. Dalton, David P. Smith
Published 2019-04-01

Correction: Iron Accumulates in Huntington’s Disease Neurons: Protection by Deferoxamine

by Jianfang Chen, Eileen Marks, Barry Lai, Zhaojie Zhang, James A. Duce, Linh Q. Lam, Irene Volitakis, Ashley I. Bush, Steven Hersch, Jonathan H. Fox
Published 2013-01-01

Correction: Iron Accumulates in Huntington’s Disease Neurons: Protection by Deferoxamine.

by Jianfang Chen, Eileen Marks, Barry Lai, Zhaojie Zhang, James A. Duce, Linh Q. Lam, Irene Volitakis, Ashley I. Bush, Steven Hersch, Jonathan H. Fox
Published 2013-01-01

Iron accumulates in Huntington's disease neurons: protection by deferoxamine.

by Jianfang Chen, Eileen Marks, Barry Lai, Zhaojie Zhang, James A Duce, Linh Q Lam, Irene Volitakis, Ashley I Bush, Steven Hersch, Jonathan H Fox
Published 2013-01-01

iPSC-derived neuronal models of PANK2-associated neurodegeneration reveal mitochondrial dysfunction contributing to early disease.

by Charles Arber, Plamena R Angelova, Sarah Wiethoff, Yugo Tsuchiya, Francesca Mazzacuva, Elisavet Preza, Kailash P Bhatia, Kevin Mills, Ivan Gout, Andrey Y Abramov, John Hardy, James A Duce, Henry Houlden, Selina Wray
Published 2017-01-01