A Tangled Web - Tau and Sporadic Parkinson's Disease

by Selina Wray, Patrick A Lewis
Published 2010-12-01

Stem cell models of Alzheimer’s disease: progress and challenges

by Charles Arber, Christopher Lovejoy, Selina Wray
Published 2017-06-01

Computational modelling of pathogenic protein spread in neurodegenerative diseases.

by Konstantinos Georgiadis, Selina Wray, Sébastien Ourselin, Jason D Warren, Marc Modat
Published 2018-01-01

Genetically engineered MAPT 10+16 mutation causes pathophysiological excitability of human iPSC-derived neurons related to 4R tau-induced dementia

by Olga Kopach, Noemí Esteras, Selina Wray, Andrey Y. Abramov, Dmitri A. Rusakov
Published 2021-07-01

Mitochondrial hyperpolarization in iPSC-derived neurons from patients of FTDP-17 with 10+16 MAPT mutation leads to oxidative stress and neurodegeneration

by Noemí Esteras, Jonathan D. Rohrer, John Hardy, Selina Wray, Andrey Y. Abramov
Published 2017-08-01

A new TAO kinase inhibitor reduces tau phosphorylation at sites associated with neurodegeneration in human tauopathies

by Caterina Giacomini, Chuay-Yeng Koo, Natalia Yankova, Ignatius A. Tavares, Selina Wray, Wendy Noble, Diane P. Hanger, Jonathan D. H. Morris
Published 2018-05-01

Amyloid β peptides are differentially vulnerable to preanalytical surface exposure, an effect incompletely mitigated by the use of ratios

by Jamie Toombs, Martha S. Foiani, Henrietta Wellington, Ross W. Paterson, Charles Arber, Amanda Heslegrave, Michael P. Lunn, Jonathan M. Schott, Selina Wray, Henrik Zetterberg
Published 2018-01-01

Conceptualising and Understanding Artistic Creativity in the Dementias: Interdisciplinary Approaches to Research and Practise

by Paul M. Camic, Paul M. Camic, Sebastian J. Crutch, Sebastian J. Crutch, Charlie Murphy, Nicholas C. Firth, Nicholas C. Firth, Emma Harding, Emma Harding, Charles R. Harrison, Susannah Howard, Susannah Howard, Sarah Strohmaier, Sarah Strohmaier, Janneke Van Leewen, Janneke Van Leewen, Julian West, Julian West, Gill Windle, Gill Windle, Selina Wray, Selina Wray, Hannah Zeilig, Hannah Zeilig
Published 2018-10-01

Excess α-synuclein compromises phagocytosis in iPSC-derived macrophages

by Walther Haenseler, Federico Zambon, Heyne Lee, Jane Vowles, Federica Rinaldi, Galbha Duggal, Henry Houlden, Katrina Gwinn, Selina Wray, Kelvin C. Luk, Richard Wade-Martins, William S. James, Sally A. Cowley
Published 2017-08-01

Tau Protein Hyperphosphorylation and Aggregation in Alzheimer’s Disease and Other Tauopathies, and Possible Neuroprotective Strategies

by Goran Šimić, Mirjana Babić Leko, Selina Wray, Charles Harrington, Ivana Delalle, Nataša Jovanov-Milošević, Danira Bažadona, Luc Buée, Rohan de Silva, Giuseppe Di Giovanni, Claude Wischik, Patrick R. Hof
Published 2016-01-01

iPSC-derived neuronal models of PANK2-associated neurodegeneration reveal mitochondrial dysfunction contributing to early disease.

by Charles Arber, Plamena R Angelova, Sarah Wiethoff, Yugo Tsuchiya, Francesca Mazzacuva, Elisavet Preza, Kailash P Bhatia, Kevin Mills, Ivan Gout, Andrey Y Abramov, John Hardy, James A Duce, Henry Houlden, Selina Wray
Published 2017-01-01

Familial Alzheimer’s Disease Mutations in PSEN1 Lead to Premature Human Stem Cell Neurogenesis

by Charles Arber, Christopher Lovejoy, Lachlan Harris, Nanet Willumsen, Argyro Alatza, Jackie M. Casey, Georgie Lines, Caoimhe Kerins, Anika K. Mueller, Henrik Zetterberg, John Hardy, Natalie S. Ryan, Nick C. Fox, Tammaryn Lashley, Selina Wray
Published 2021-01-01

Genetically Engineered iPSC-Derived FTDP-17 MAPT Neurons Display Mutation-Specific Neurodegenerative and Neurodevelopmental Phenotypes

by An Verheyen, Annick Diels, Joke Reumers, Kirsten Van Hoorde, Ilse Van den Wyngaert, Constantin van Outryve d’Ydewalle, An De Bondt, Jacobine Kuijlaars, Louis De Muynck, Ronald De Hoogt, Alexis Bretteville, Steffen Jaensch, Arjan Buist, Alfredo Cabrera-Socorro, Selina Wray, Andreas Ebneth, Peter Roevens, Ines Royaux, Pieter J. Peeters
Published 2018-08-01

Progressive Motor Neuron Pathology and the Role of Astrocytes in a Human Stem Cell Model of VCP-Related ALS

by Claire E. Hall, Zhi Yao, Minee Choi, Giulia E. Tyzack, Andrea Serio, Raphaelle Luisier, Jasmine Harley, Elisavet Preza, Charlie Arber, Sarah J. Crisp, P. Marc D. Watson, Dimitri M. Kullmann, Andrey Y. Abramov, Selina Wray, Russell Burley, Samantha H.Y. Loh, L. Miguel Martins, Molly M. Stevens, Nicholas M. Luscombe, Christopher R. Sibley, Andras Lakatos, Jernej Ule, Sonia Gandhi, Rickie Patani
Published 2017-05-01

Preparatory planning framework for Created Out of Mind: Shaping perceptions of dementia through art and science [version 1; referees: 2 approved]

by Emilie Brotherhood, Philip Ball, Paul M Camic, Caroline Evans, Nick Fox, Charlie Murphy, Fergus Walsh, Julian West, Gill Windle, Sarah Billiald, Nicholas Firth, Emma Harding, Charles Harrison, Catherine Holloway, Susanna Howard, Roberta McKee-Jackson, Esther Jones, Janette Junghaus, Harriet Martin, Kailey Nolan, Bridie Rollins, Lillian Shapiro, Lionel Shapiro, Jane Twigg, Janneke van Leeuwen, Jill Walton, Jason Warren, Selina Wray, Keir Yong, Hannah Zeilig, Sebastian Crutch
Published 2017-11-01

G‐quadruplex‐binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo

by Roberto Simone, Rubika Balendra, Thomas G Moens, Elisavet Preza, Katherine M Wilson, Amanda Heslegrave, Nathan S Woodling, Teresa Niccoli, Javier Gilbert‐Jaramillo, Samir Abdelkarim, Emma L Clayton, Mica Clarke, Marie‐Therese Konrad, Andrew J Nicoll, Jamie S Mitchell, Andrea Calvo, Adriano Chio, Henry Houlden, James M Polke, Mohamed A Ismail, Chad E Stephens, Tam Vo, Abdelbasset A Farahat, W David Wilson, David W Boykin, Henrik Zetterberg, Linda Partridge, Selina Wray, Gary Parkinson, Stephen Neidle, Rickie Patani, Pietro Fratta, Adrian M Isaacs
Published 2018-01-01

Creation of an open-access, mutation-defined fibroblast resource for neurological disease research.

by Selina Wray, Matthew Self, NINDS Parkinson's Disease iPSC Consortium, NINDS Huntington's Disease iPSC Consortium, NINDS ALS iPSC Consortium, Patrick A Lewis, Jan-Willem Taanman, Natalie S Ryan, Colin J Mahoney, Yuying Liang, Michael J Devine, Una-Marie Sheerin, Henry Houlden, Huw R Morris, Daniel Healy, Jose-Felix Marti-Masso, Elisavet Preza, Suzanne Barker, Margaret Sutherland, Roderick A Corriveau, Michael D'Andrea, Anthony H V Schapira, Ryan J Uitti, Mark Guttman, Grzegorz Opala, Barbara Jasinska-Myga, Andreas Puschmann, Christer Nilsson, Alberto J Espay, Jaroslaw Slawek, Ludwig Gutmann, Bradley F Boeve, Kevin Boylan, A Jon Stoessl, Owen A Ross, Nicholas J Maragakis, Jay Van Gerpen, Melissa Gerstenhaber, Katrina Gwinn, Ted M Dawson, Ole Isacson, Karen S Marder, Lorraine N Clark, Serge E Przedborski, Steven Finkbeiner, Jeffrey D Rothstein, Zbigniew K Wszolek, Martin N Rossor, John Hardy
Published 2012-01-01