Autoencoder-based cluster ensembles for single-cell RNA-seq data analysis

by Thomas A. Geddes, Taiyun Kim, Lihao Nan, James G. Burchfield, Jean Y. H. Yang, Dacheng Tao, Pengyi Yang
Published 2019-12-01

The role of the Niemann-Pick disease, type C1 protein in adipocyte insulin action.

by Rachael Fletcher, Christopher Gribben, Xiuquan Ma, James G Burchfield, Kristen C Thomas, James R Krycer, David E James, Daniel J Fazakerley
Published 2014-01-01

Signaling Heterogeneity is Defined by Pathway Architecture and Intercellular Variability in Protein Expression

by Dougall Norris, Pengyi Yang, Sung-Young Shin, Alison L. Kearney, Hani Jieun Kim, Thomas Geddes, Alistair M. Senior, Daniel J. Fazakerley, Lan K. Nguyen, David E. James, James G. Burchfield
Published 2021-02-01

Glucose homeostasis in mice is transglutaminase 2 independent.

by Siiri E Iismaa, Mark Aplin, Sara Holman, Ting W Yiu, Kristy Jackson, James G Burchfield, Christopher J Mitchell, Liam O'Reilly, Aimee Davenport, James Cantley, Carsten Schmitz-Peiffer, Trevor J Biden, Gregory J Cooney, Robert M Graham
Published 2013-01-01

Akt phosphorylates insulin receptor substrate to limit PI3K-mediated PIP3 synthesis

by Alison L Kearney, Dougall M Norris, Milad Ghomlaghi, Martin Kin Lok Wong, Sean J Humphrey, Luke Carroll, Guang Yang, Kristen C Cooke, Pengyi Yang, Thomas A Geddes, Sungyoung Shin, Daniel J Fazakerley, Lan K Nguyen, David E James, James G Burchfield
Published 2021-07-01

Global redox proteome and phosphoproteome analysis reveals redox switch in Akt

by Zhiduan Su, James G. Burchfield, Pengyi Yang, Sean J. Humphrey, Guang Yang, Deanne Francis, Sabina Yasmin, Sung-Young Shin, Dougall M. Norris, Alison L. Kearney, Miro A. Astore, Jonathan Scavuzzo, Kelsey H. Fisher-Wellman, Qiao-Ping Wang, Benjamin L. Parker, G. Gregory Neely, Fatemeh Vafaee, Joyce Chiu, Reichelle Yeo, Philip J. Hogg, Daniel J. Fazakerley, Lan K. Nguyen, Serdar Kuyucak, David E. James
Published 2019-12-01

Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance

by Daniel J Fazakerley, Rima Chaudhuri, Pengyi Yang, Ghassan J Maghzal, Kristen C Thomas, James R Krycer, Sean J Humphrey, Benjamin L Parker, Kelsey H Fisher-Wellman, Christopher C Meoli, Nolan J Hoffman, Ciana Diskin, James G Burchfield, Mark J Cowley, Warren Kaplan, Zora Modrusan, Ganesh Kolumam, Jean YH Yang, Daniel L Chen, Dorit Samocha-Bonet, Jerry R Greenfield, Kyle L Hoehn, Roland Stocker, David E James
Published 2018-02-01