Characterization of a dual function macrocyclase enables design and use of efficient macrocyclization substrates

by Clarissa M. Czekster, Hannes Ludewig, Stephen A. McMahon, James H. Naismith
Published 2017-10-01

Preacinetobactin not acinetobactin is essential for iron uptake by the BauA transporter of the pathogen Acinetobacter baumannii

by Lucile Moynié, Ilaria Serra, Mariano A Scorciapino, Emilia Oueis, Malcolm GP Page, Matteo Ceccarelli, James H Naismith
Published 2018-12-01

Biochemical and Structural Analysis of the Role of the Wlb Gene Locus in Bordetella Pertussis Lipopolysaccharide Biosynthesis

by Velupillai S. Kannathasan, Chang J. Dong, Corin Wing, Andrew Preston, Duncan J. Maskell, James H. Naismith, Robert A. Field
Published 2002-01-01

Use of isotopically labeled substrates reveals kinetic differences between human and bacterial serine palmitoyltransferase

by Peter J. Harrison, Kenneth Gable, Niranjanakumari Somashekarappa, Van Kelly, David J. Clarke, James H. Naismith, Teresa M. Dunn, Dominic J. Campopiano
Published 2019-05-01

Erratum: Use of isotopically labeled substrates reveals kinetic differences between human and bacterial serine palmitoyltransferase

by Peter J. Harrison, Kenneth Gable, Niranjanakumari Somashekarappa, Van Kelly, David J. Clarke, James H. Naismith, Teresa M. Dunn, Dominic J. Campopiano
Published 2019-08-01

Single Cell Cryo-Soft X-ray Tomography Shows That Each <i>Chlamydia Trachomatis</i> Inclusion Is a Unique Community of Bacteria

by Patrick Phillips, James M. Parkhurst, Ilias Kounatidis, Chidinma Okolo, Thomas M. Fish, James H. Naismith, Martin A. Walsh, Maria Harkiolaki, Maud Dumoux
Published 2021-08-01

Rift Valley fever phlebovirus NSs protein core domain structure suggests molecular basis for nuclear filaments

by Michal Barski, Benjamin Brennan, Ona K Miller, Jane A Potter, Swetha Vijayakrishnan, David Bhella, James H Naismith, Richard M Elliott, Ulrich Schwarz-Linek
Published 2017-09-01

The use of nanobodies in a sensitive ELISA test for SARS-CoV-2 Spike 1 protein

by Georgina C. Girt, Abirami Lakshminarayanan, Jiandong Huo, Joshua Dormon, Chelsea Norman, Babak Afrough, Adam Harding, William James, Raymond J. Owens, James H. Naismith
Published 2021-09-01

Pironetin reacts covalently with cysteine-316 of α-tubulin to destabilize microtubule

by Jianhong Yang, Yuxi Wang, Taijing Wang, Jian Jiang, Catherine H. Botting, Huanting Liu, Qiang Chen, Jinliang Yang, James H. Naismith, Xiaofeng Zhu, Lijuan Chen
Published 2016-06-01

The molecular basis of regulation of bacterial capsule assembly by Wzc

by Yun Yang, Jiwei Liu, Bradley R. Clarke, Laura Seidel, Jani R. Bolla, Philip N. Ward, Peijun Zhang, Carol V. Robinson, Chris Whitfield, James H. Naismith
Published 2021-07-01

Hydrophobic recognition allows the glycosyltransferase UGT76G1 to catalyze its substrate in two orientations

by Ting Yang, Jinzhu Zhang, Dan Ke, Wenxian Yang, Minghai Tang, Jian Jiang, Guo Cheng, Jianshu Li, Wei Cheng, Yuquan Wei, Qintong Li, James H. Naismith, Xiaofeng Zhu
Published 2019-07-01

Altered antibiotic transport in OmpC mutants isolated from a series of clinical strains of multi-drug resistant E. coli.

by Hubing Lou, Min Chen, Susan S Black, Simon R Bushell, Matteo Ceccarelli, Tivadar Mach, Konstantinos Beis, Alison S Low, Victoria A Bamford, Ian R Booth, Hagan Bayley, James H Naismith
Published 2011-01-01

The respiratory arsenite oxidase: structure and the role of residues surrounding the rieske cluster.

by Thomas P Warelow, Muse Oke, Barbara Schoepp-Cothenet, Jan U Dahl, Nicole Bruselat, Ganesh N Sivalingam, Silke Leimkühler, Konstantinos Thalassinos, Ulrike Kappler, James H Naismith, Joanne M Santini
Published 2013-01-01

The complex of ferric-enterobactin with its transporter from Pseudomonas aeruginosa suggests a two-site model

by Lucile Moynié, Stefan Milenkovic, Gaëtan L. A. Mislin, Véronique Gasser, Giuliano Malloci, Etienne Baco, Rory P. McCaughan, Malcolm G. P. Page, Isabelle J. Schalk, Matteo Ceccarelli, James H. Naismith
Published 2019-08-01

A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19

by Jiandong Huo, Halina Mikolajek, Audrey Le Bas, Jordan J. Clark, Parul Sharma, Anja Kipar, Joshua Dormon, Chelsea Norman, Miriam Weckener, Daniel K. Clare, Peter J. Harrison, Julia A. Tree, Karen R. Buttigieg, Francisco J. Salguero, Robert Watson, Daniel Knott, Oliver Carnell, Didier Ngabo, Michael J. Elmore, Susan Fotheringham, Adam Harding, Lucile Moynié, Philip N. Ward, Maud Dumoux, Tessa Prince, Yper Hall, Julian A. Hiscox, Andrew Owen, William James, Miles W. Carroll, James P. Stewart, James H. Naismith, Raymond J. Owens
Published 2021-09-01