Effect of Anticancer Quinones on Reactive Oxygen Production by Adult Rat Heart Myocytes

by James H. Doroshow
Published 2020-01-01

Mechanisms of Anthracycline-Enhanced Reactive Oxygen Metabolism in Tumor Cells

by James H. Doroshow
Published 2019-01-01

Control of doxorubicin-induced, reactive oxygen-related apoptosis by glutathione peroxidase 1 in cardiac fibroblasts

by James H. Doroshow, R. Steven Esworthy, Fong-Fong Chu
Published 2020-03-01

Role of the microbiota in ileitis of a mouse model of inflammatory bowel disease—Glutathione peroxide isoenzymes 1 and 2‐double knockout mice on a C57BL background

by Fong‐Fong Chu, R. Steven Esworthy, Binghui Shen, James H. Doroshow
Published 2020-10-01

Longitudinal Transcriptional Response of Glycosylation-Related Genes, Regulators, and Targets in Cancer Cell Lines Treated With 11 Antitumor Agents

by Julia Krushkal, Yingdong Zhao, Curtis Hose, Anne Monks, James H Doroshow, Richard Simon
Published 2017-12-01

Analysis of candidate colitis genes in the Gdac1 locus of mice deficient in glutathione peroxidase-1 and -2.

by R Steven Esworthy, Byung-Wook Kim, Guillermo E Rivas, Thomas L Leto, James H Doroshow, Fong-Fong Chu
Published 2012-01-01

Deficiency in Duox2 activity alleviates ileitis in GPx1- and GPx2-knockout mice without affecting apoptosis incidence in the crypt epithelium

by Fong-Fong Chu, R. Steven Esworthy, James H. Doroshow, Helmut Grasberger, Agnes Donko, Thomas L. Leto, Qiang Gao, Binghui Shen
Published 2017-04-01

Modeling pharmacodynamic response to the poly(ADP-Ribose) polymerase inhibitor ABT-888 in human peripheral blood mononuclear cells.

by Jiuping Ji, Robert J Kinders, Yiping Zhang, Larry Rubinstein, Shivaani Kummar, Ralph E Parchment, Joseph E Tomaszewski, James H Doroshow
Published 2011-01-01

Publisher Correction: Converting tabular data into images for deep learning with convolutional neural networks

by Yitan Zhu, Thomas Brettin, Fangfang Xia, Alexander Partin, Maulik Shukla, Hyunseung Yoo, Yvonne A. Evrard, James H. Doroshow, Rick L. Stevens
Published 2021-07-01

A spontaneously metastatic model of bladder cancer: imaging characterization

by James L. Tatum, Joseph D. Kalen, Paula M. Jacobs, Lilia V. Ileva, Lisa A. Riffle, Melinda G. Hollingshead, James H. Doroshow
Published 2019-12-01

Enhanced Co-Expression Extrapolation (COXEN) Gene Selection Method for Building Anti-Cancer Drug Response Prediction Models

by Yitan Zhu, Thomas Brettin, Yvonne A. Evrard, Fangfang Xia, Alexander Partin, Maulik Shukla, Hyunseung Yoo, James H. Doroshow, Rick L. Stevens
Published 2020-09-01

Converting tabular data into images for deep learning with convolutional neural networks

by Yitan Zhu, Thomas Brettin, Fangfang Xia, Alexander Partin, Maulik Shukla, Hyunseung Yoo, Yvonne A. Evrard, James H. Doroshow, Rick L. Stevens
Published 2021-05-01

TET2 and DNMT3A mutations and exceptional response to 4′-thio-2′-deoxycytidine in human solid tumor models

by Sherry X. Yang, Melinda Hollingshead, Larry Rubinstein, Dat Nguyen, Angelo B. A. Larenjeira, Robert J. Kinders, Michael Difilippantonio, James H. Doroshow
Published 2021-05-01

TPM, FPKM, or Normalized Counts? A Comparative Study of Quantification Measures for the Analysis of RNA-seq Data from the NCI Patient-Derived Models Repository

by Yingdong Zhao, Ming-Chung Li, Mariam M. Konaté, Li Chen, Biswajit Das, Chris Karlovich, P. Mickey Williams, Yvonne A. Evrard, James H. Doroshow, Lisa M. McShane
Published 2021-06-01

Learning curves for drug response prediction in cancer cell lines

by Alexander Partin, Thomas Brettin, Yvonne A. Evrard, Yitan Zhu, Hyunseung Yoo, Fangfang Xia, Songhao Jiang, Austin Clyde, Maulik Shukla, Michael Fonstein, James H. Doroshow, Rick L. Stevens
Published 2021-05-01

NADPH oxidase 1 is highly expressed in human large and small bowel cancers.

by Jiamo Lu, Guojian Jiang, Yongzhong Wu, Smitha Antony, Jennifer L Meitzler, Agnes Juhasz, Han Liu, Krishnendu Roy, Hala Makhlouf, Rodrigo Chuaqui, Donna Butcher, Mariam M Konaté, James H Doroshow
Published 2020-01-01

Design and Implementation of the Pre-Clinical DICOM Standard in Multi-Cohort Murine Studies

by Joseph D. Kalen, David A. Clunie, Yanling Liu, James L. Tatum, Paula M. Jacobs, Justin Kirby, John B. Freymann, Ulrike Wagner, Kirk E. Smith, Christian Suloway, James H. Doroshow
Published 2021-02-01

NCI-60 whole exome sequencing and pharmacological CellMiner analyses.

by William C Reinhold, Sudhir Varma, Fabricio Sousa, Margot Sunshine, Ogan D Abaan, Sean R Davis, Spencer W Reinhold, Kurt W Kohn, Joel Morris, Paul S Meltzer, James H Doroshow, Yves Pommier
Published 2014-01-01

Predicting tumor cell line response to drug pairs with deep learning

by Fangfang Xia, Maulik Shukla, Thomas Brettin, Cristina Garcia-Cardona, Judith Cohn, Jonathan E. Allen, Sergei Maslov, Susan L. Holbeck, James H. Doroshow, Yvonne A. Evrard, Eric A. Stahlberg, Rick L. Stevens
Published 2018-12-01

Antibody-independent capture of circulating tumor cells of non-epithelial origin with the ApoStream® system.

by Priya Balasubramanian, Robert J Kinders, Shivaani Kummar, Vishal Gupta, David Hasegawa, Anoop Menachery, Scott M Lawrence, Lihua Wang, Katherine Ferry-Galow, Darren Davis, Ralph E Parchment, Joseph E Tomaszewski, James H Doroshow
Published 2017-01-01