Progress on the Prevention and Treatment of Hantavirus Disease

by Rebecca L. Brocato, Jay W. Hooper
Published 2019-07-01

Ribavirin Protects Syrian Hamsters against Lethal Hantavirus Pulmonary Syndrome — After Intranasal Exposure to Andes Virus

by Jay W. Hooper, Colleen B. Jonsson, Monica Ogg, Jeremy V. Camp
Published 2013-11-01

DNA vaccine-generated duck polyclonal antibodies as a postexposure prophylactic to prevent hantavirus pulmonary syndrome (HPS).

by Rebecca Brocato, Matthew Josleyn, John Ballantyne, Pablo Vial, Jay W Hooper
Published 2012-01-01

A lethal disease model for New World hantaviruses using immunosuppressed Syrian hamsters.

by Valentijn Vergote, Lies Laenen, Bert Vanmechelen, Marc Van Ranst, Erik Verbeken, Jay W Hooper, Piet Maes
Published 2017-10-01

Intranasal monkeypox marmoset model: Prophylactic antibody treatment provides benefit against severe monkeypox virus disease.

by Eric M Mucker, Suzanne E Wollen-Roberts, Adrienne Kimmel, Josh Shamblin, Darryl Sampey, Jay W Hooper
Published 2018-06-01

An attenuated Machupo virus with a disrupted L-segment intergenic region protects guinea pigs against lethal Guanarito virus infection

by Joseph W. Golden, Brett Beitzel, Jason T. Ladner, Eric M. Mucker, Steven A. Kwilas, Gustavo Palacios, Jay W. Hooper
Published 2017-07-01

Side-by-side comparison of gene-based smallpox vaccine with MVA in nonhuman primates.

by Joseph W Golden, Matthew Josleyn, Eric M Mucker, Chien-Fu Hung, Peter T Loudon, T C Wu, Jay W Hooper
Published 2012-01-01

Protective efficacy of a SARS-CoV-2 DNA vaccine in wild-type and immunosuppressed Syrian hamsters

by Rebecca L. Brocato, Steven A. Kwilas, Robert K. Kim, Xiankun Zeng, Lucia M. Principe, Jeffrey M. Smith, Jay W. Hooper
Published 2021-01-01

Comparison of transcriptional responses between pathogenic and nonpathogenic hantavirus infections in Syrian hamsters using NanoString.

by Rebecca L Brocato, Louis A Altamura, Brian D Carey, Casey C Perley, Candace D Blancett, Timothy D Minogue, Jay W Hooper
Published 2021-08-01

Gastrointestinal Tract As Entry Route for Hantavirus Infection

by Peter T. Witkowski, Casey C. Perley, Rebecca L. Brocato, Jay W. Hooper, Christian Jürgensen, Jörg-Dieter Schulzke, Detlev H. Krüger, Roland Bücker
Published 2017-09-01

Three asymptomatic animal infection models of hemorrhagic fever with renal syndrome caused by hantaviruses.

by Casey C Perley, Rebecca L Brocato, Steven A Kwilas, Sharon Daye, Alicia Moreau, Donald K Nichols, Kelly S Wetzel, Joshua Shamblin, Jay W Hooper
Published 2019-01-01

Human Polyclonal Antibodies Produced from Transchromosomal Bovine Provides Prophylactic and Therapeutic Protections Against Zika Virus Infection in <i>STAT2</i> KO Syrian Hamsters

by Venkatraman Siddharthan, Jinxin Miao, Arnaud J Van Wettere, Rong Li, Hua Wu, Eddie Sullivan, Jinan Jiao, Jay W. Hooper, David Safronetz, John D. Morrey, Justin G. Julander, Zhongde Wang
Published 2019-01-01

Antiviral Biologic Produced in DNA Vaccine/Goose Platform Protects Hamsters Against Hantavirus Pulmonary Syndrome When Administered Post-exposure.

by Nicole Haese, Rebecca L Brocato, Thomas Henderson, Matthew L Nilles, Steve A Kwilas, Matthew D Josleyn, Christopher D Hammerbeck, James Schiltz, Michael Royals, John Ballantyne, Jay W Hooper, David S Bradley
Published 2015-01-01

Anti-HFRS Human IgG Produced in Transchromosomic Bovines Has Potent Hantavirus Neutralizing Activity and Is Protective in Animal Models

by Casey C. Perley, Rebecca L. Brocato, Hua Wu, Christoph Bausch, Priya P. Karmali, Jerel B. Vega, Melanie V. Cohen, Brandon Somerville, Steven A. Kwilas, Lucia M. Principe, Joshua Shamblin, Padmanabh Chivukula, Eddie Sullivan, Jay W. Hooper
Published 2020-05-01

Human Polyclonal Antibodies Produced through DNA Vaccination of Transchromosomal Cattle Provide Mice with Post-Exposure Protection against Lethal Zaire and Sudan Ebolaviruses.

by Callie E Bounds, Steven A Kwilas, Ana I Kuehne, Jennifer M Brannan, Russell R Bakken, John M Dye, Jay W Hooper, Lesley C Dupuy, Barry Ellefsen, Drew Hannaman, Hua Wu, Jin-an Jiao, Eddie J Sullivan, Connie S Schmaljohn
Published 2015-01-01

Comparison of VSV Pseudovirus and Focus Reduction Neutralization Assays for Measurement of Anti-Andes orthohantavirus Neutralizing Antibodies in Patient Samples

by Cecilia Vial, Annalis Whitaker, Annalis Whitaker, Jan Wilhelm, Jan Wilhelm, Jimena Ovalle, Ruth Perez, Francisca Valdivieso, Marcela Ferres, Constanza Martinez-Valdebenito, Philip Eisenhauer, Gregory J. Mertz, Jay W. Hooper, Jason W. Botten, Jason W. Botten, Pablo A. Vial, Pablo A. Vial
Published 2020-09-01

Human angiotensin-converting enzyme 2 transgenic mice infected with SARS-CoV-2 develop severe and fatal respiratory disease

by Joseph W. Golden, Curtis R. Cline, Xiankun Zeng, Aura R. Garrison, Brian D. Carey, Eric M. Mucker, Lauren E. White, Joshua D. Shamblin, Rebecca L. Brocato, Jun Liu, April M. Babka, Hypaitia B. Rauch, Jeffrey M. Smith, Bradley S. Hollidge, Collin Fitzpatrick, Catherine V. Badger, Jay W. Hooper
Published 2020-10-01

Broad and potently neutralizing monoclonal antibodies isolated from human survivors of New World hantavirus infection

by Taylor B. Engdahl, Natalia A. Kuzmina, Adam J. Ronk, Chad E. Mire, Matthew A. Hyde, Nurgun Kose, Matthew D. Josleyn, Rachel E. Sutton, Apoorva Mehta, Rachael M. Wolters, Nicole M. Lloyd, Francisca R. Valdivieso, Thomas G. Ksiazek, Jay W. Hooper, Alexander Bukreyev, James E. Crowe, Jr.
Published 2021-05-01

Correction: A prophylactic multivalent vaccine against different filovirus species is immunogenic and provides protection from lethal infections with Ebolavirus and Marburgvirus sp...

by Benoit Callendret, Jort Vellinga, Kerstin Wunderlich, Ariane Rodriguez, Robin Steigerwald, Ulrike Dirmeier, Cedric Cheminay, Ariane Volkmann, Trevor Brasel, Ricardo Carrion, Luis D Giavedoni, Jean L Patterson, Chad E Mire, Thomas W Geisbert, Jay W Hooper, Mo Weijtens, Jutta Hartkoorn-Pasma, Jerome Custers, Maria Grazia Pau, Hanneke Schuitemaker, Roland Zahn
Published 2018-01-01

A prophylactic multivalent vaccine against different filovirus species is immunogenic and provides protection from lethal infections with Ebolavirus and Marburgvirus species in non...

by Benoit Callendret, Jort Vellinga, Kerstin Wunderlich, Ariane Rodriguez, Robin Steigerwald, Ulrike Dirmeier, Cedric Cheminay, Ariane Volkmann, Trevor Brasel, Ricardo Carrion, Luis D Giavedoni, Jean L Patterson, Chad E Mire, Thomas W Geisbert, Jay W Hooper, Mo Weijtens, Jutta Hartkoorn-Pasma, Jerome Custers, Maria Grazia Pau, Hanneke Schuitemaker, Roland Zahn
Published 2018-01-01