Nonhuman Primate Models of Chikungunya Virus Infection and Disease (CHIKV NHP Model)

by Rebecca Broeckel, Nicole Haese, Ilhem Messaoudi, Daniel N. Streblow
Published 2015-09-01

Pyrimidone inhibitors targeting Chikungunya Virus nsP3 macrodomain by fragment-based drug design.

by Sixue Zhang, Atefeh Garzan, Nicole Haese, Robert Bostwick, Yohanka Martinez-Gzegozewska, Lynn Rasmussen, Daniel N Streblow, Mark T Haise, Ashish K Pathak, Corinne E Augelli-Szafran, Mousheng Wu
Published 2021-01-01

Antiviral Biologic Produced in DNA Vaccine/Goose Platform Protects Hamsters Against Hantavirus Pulmonary Syndrome When Administered Post-exposure.

by Nicole Haese, Rebecca L Brocato, Thomas Henderson, Matthew L Nilles, Steve A Kwilas, Matthew D Josleyn, Christopher D Hammerbeck, James Schiltz, Michael Royals, John Ballantyne, Jay W Hooper, David S Bradley
Published 2015-01-01

Vaccine-Induced Skewing of T Cell Responses Protects Against Chikungunya Virus Disease

by Rebecca M. Broeckel, Nicole Haese, Takeshi Ando, Igor Dmitriev, Craig N. Kreklywich, John Powers, Michael Denton, Patricia Smith, Thomas E. Morrison, Mark Heise, Mark Heise, Victor DeFilippis, Ilhem Messaoudi, David T. Curiel, Daniel N. Streblow, Daniel N. Streblow
Published 2019-10-01

Additives for vaccine storage to improve thermal stability of adenoviruses from hours to months

by Maria Pelliccia, Patrizia Andreozzi, Jayson Paulose, Marco D’Alicarnasso, Valeria Cagno, Manuela Donalisio, Andrea Civra, Rebecca M. Broeckel, Nicole Haese, Paulo Jacob Silva, Randy P. Carney, Varpu Marjomäki, Daniel N. Streblow, David Lembo, Francesco Stellacci, Vincenzo Vitelli, Silke Krol
Published 2016-11-01

Therapeutic administration of a recombinant human monoclonal antibody reduces the severity of chikungunya virus disease in rhesus macaques.

by Rebecca Broeckel, Julie M Fox, Nicole Haese, Craig N Kreklywich, Soila Sukulpovi-Petty, Alfred Legasse, Patricia P Smith, Michael Denton, Carsten Corvey, Shiv Krishnan, Lois M A Colgin, Rebecca M Ducore, Anne D Lewis, Michael K Axthelm, Marie Mandron, Pierre Cortez, Jonathan Rothblatt, Ercole Rao, Ingo Focken, Kara Carter, Gopal Sapparapau, James E Crowe, Michael S Diamond, Daniel N Streblow
Published 2017-06-01

Zika virus infection in pregnant rhesus macaques causes placental dysfunction and immunopathology

by Alec J. Hirsch, Victoria H. J. Roberts, Peta L. Grigsby, Nicole Haese, Matthias C. Schabel, Xiaojie Wang, Jamie O. Lo, Zheng Liu, Christopher D. Kroenke, Jessica L. Smith, Meredith Kelleher, Rebecca Broeckel, Craig N. Kreklywich, Christopher J. Parkins, Michael Denton, Patricia Smith, Victor DeFilippis, William Messer, Jay A. Nelson, Jon D. Hennebold, Marjorie Grafe, Lois Colgin, Anne Lewis, Rebecca Ducore, Tonya Swanson, Alfred W. Legasse, Michael K. Axthelm, Rhonda MacAllister, Ashlee V. Moses, Terry K. Morgan, Antonio E. Frias, Daniel N. Streblow
Published 2018-01-01