Recent advances in immunotherapies: from infection and autoimmunity, to cancer, and back again

by Samantha L. Bucktrout, Jeffrey A. Bluestone, Fred Ramsdell
Published 2018-10-01

Thymically-derived Foxp3+ regulatory T cells are the primary regulators of type 1 diabetes in the non-obese diabetic mouse model.

by Daniel R Holohan, Frédéric Van Gool, Jeffrey A Bluestone
Published 2019-01-01

DGCR8-mediated production of canonical microRNAs is critical for regulatory T cell function and stability.

by Lukas T Jeker, Xuyu Zhou, Robert Blelloch, Jeffrey A Bluestone
Published 2013-01-01

Peripherally induced Tregs – Role in immune homeostasis and autoimmunity

by Mahesh eYadav, Jeffrey A Bluestone, Stephen eStephan
Published 2013-08-01

Inducing and administering Tregs to treat human disease

by Ana Luisa Perdigoto, Lucienne eChatenoud, Jeffrey A Bluestone, Kevan C Herold
Published 2016-01-01

Aberrant innate immune activation following tissue injury impairs pancreatic regeneration.

by Alexandra E Folias, Cristina Penaranda, Anthony L Su, Jeffrey A Bluestone, Matthias Hebrok
Published 2014-01-01

NK cells are not required for spontaneous autoimmune diabetes in NOD mice.

by Joshua N Beilke, Craig T Meagher, Karoline Hosiawa, Marine Champsaur, Jeffrey A Bluestone, Lewis L Lanier
Published 2012-01-01

Pathological conversion of regulatory T cells is associated with loss of allotolerance

by Jing Hua, Takenori Inomata, Yihe Chen, William Foulsham, William Stevenson, Tina Shiang, Jeffrey A. Bluestone, Reza Dana
Published 2018-05-01

Retinoic acid and rapamycin differentially affect and synergistically promote the ex vivo expansion of natural human T regulatory cells.

by Tatiana N Golovina, Tatiana Mikheeva, Todd M Brusko, Bruce R Blazar, Jeffrey A Bluestone, James L Riley
Published 2011-01-01

Cytokines, Chemokines, and Other Biomarkers of Response for Checkpoint Inhibitor Therapy in Skin Cancer

by Jennifer A. Bridge, James C. Lee, James C. Lee, Adil Daud, James W. Wells, Jeffrey A. Bluestone
Published 2018-12-01

MicroRNA 10a marks regulatory T cells.

by Lukas T Jeker, Xuyu Zhou, Kseniya Gershberg, Dimitri de Kouchkovsky, Malika M Morar, Gustavo Stadthagen, Anders H Lund, Jeffrey A Bluestone
Published 2012-01-01

Avidity and Bystander Suppressive Capacity of Human Regulatory T Cells Expressing De Novo Autoreactive T-Cell Receptors in Type 1 Diabetes

by Wen-I Yeh, Howard R. Seay, Brittney Newby, Amanda L. Posgai, Filipa Botelho Moniz, Aaron Michels, Clayton E. Mathews, Jeffrey A. Bluestone, Todd M. Brusko
Published 2017-10-01

Production of α-galactosylceramide by a prominent member of the human gut microbiota.

by Laura C Wieland Brown, Cristina Penaranda, Purna C Kashyap, Brianna B Williams, Jon Clardy, Mitchell Kronenberg, Justin L Sonnenburg, Laurie E Comstock, Jeffrey A Bluestone, Michael A Fischbach
Published 2013-07-01

Precision Engineering of an Anti-HLA-A2 Chimeric Antigen Receptor in Regulatory T Cells for Transplant Immune Tolerance

by Yannick D. Muller, Yannick D. Muller, Leonardo M. R. Ferreira, Leonardo M. R. Ferreira, Leonardo M. R. Ferreira, Emilie Ronin, Emilie Ronin, Patrick Ho, Patrick Ho, Patrick Ho, Vinh Nguyen, Vinh Nguyen, Gaetano Faleo, Gaetano Faleo, Yu Zhou, Karim Lee, Kevin K. Leung, Nikolaos Skartsis, Nikolaos Skartsis, Anupurna M. Kaul, Arend Mulder, Frans H. J. Claas, James A. Wells, Jeffrey A. Bluestone, Jeffrey A. Bluestone, Qizhi Tang, Qizhi Tang
Published 2021-09-01

Human antigen-specific regulatory T cells generated by T cell receptor gene transfer.

by Todd M Brusko, Richard C Koya, Shirley Zhu, Michael R Lee, Amy L Putnam, Stephanie A McClymont, Michael I Nishimura, Shuhong Han, Lung-Ji Chang, Mark A Atkinson, Antoni Ribas, Jeffrey A Bluestone
Published 2010-07-01

Targeting EZH2 Reprograms Intratumoral Regulatory T Cells to Enhance Cancer Immunity

by David Wang, Jason Quiros, Kelly Mahuron, Chien-Chun Pai, Valeria Ranzani, Arabella Young, Stephanie Silveria, Tory Harwin, Arbi Abnousian, Massimiliano Pagani, Michael D. Rosenblum, Frederic Van Gool, Lawrence Fong, Jeffrey A. Bluestone, Michel DuPage
Published 2018-06-01

The CD28-Transmembrane Domain Mediates Chimeric Antigen Receptor Heterodimerization With CD28

by Yannick D. Muller, Yannick D. Muller, Yannick D. Muller, Duy P. Nguyen, Leonardo M. R. Ferreira, Leonardo M. R. Ferreira, Leonardo M. R. Ferreira, Patrick Ho, Patrick Ho, Patrick Ho, Caroline Raffin, Caroline Raffin, Roxxana Valeria Beltran Valencia, Zion Congrave-Wilson, Theodore L. Roth, Theodore L. Roth, Justin Eyquem, Frederic Van Gool, Frederic Van Gool, Alexander Marson, Alexander Marson, Alexander Marson, Laurent Perez, James A. Wells, James A. Wells, Jeffrey A. Bluestone, Jeffrey A. Bluestone, Qizhi Tang, Qizhi Tang
Published 2021-03-01

A Resource for the Conditional Ablation of microRNAs in the Mouse

by Chong Yon Park, Lukas T. Jeker, Karen Carver-Moore, Alyssia Oh, Huey Jiin Liu, Rachel Cameron, Hunter Richards, Zhongmei Li, David Adler, Yuko Yoshinaga, Maria Martinez, Michael Nefadov, Abul K. Abbas, Art Weiss, Lewis L. Lanier, Pieter J. de Jong, Jeffrey A. Bluestone, Deepak Srivastava, Michael T. McManus
Published 2012-04-01

Expansion of Human Tregs from Cryopreserved Umbilical Cord Blood for GMP-Compliant Autologous Adoptive Cell Transfer Therapy

by Howard R. Seay, Amy L. Putnam, Judit Cserny, Amanda L. Posgai, Emma H. Rosenau, John R. Wingard, Kate F. Girard, Morey Kraus, Angela P. Lares, Heather L. Brown, Katherine S. Brown, Kristi T. Balavage, Leeana D. Peters, Ashley N. Bushdorf, Mark A. Atkinson, Jeffrey A. Bluestone, Michael J. Haller, Todd M. Brusko
Published 2017-03-01

Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization

by Anke Fuchs, Mateusz Gliwiński, Nathali Grageda, Rachel Spiering, Abul K. Abbas, Silke Appel, Rosa Bacchetta, Manuela Battaglia, David Berglund, Bruce Blazar, Jeffrey A. Bluestone, Martin Bornhäuser, Anja ten Brinke, Todd M. Brusko, Nathalie Cools, Maria Cristina Cuturi, Edward Geissler, Nick Giannoukakis, Karolina Gołab, David A. Hafler, S. Marieke van Ham, Joanna Hester, Keli Hippen, Mauro Di Ianni, Natasa Ilic, John Isaacs, John Isaacs, Fadi Issa, Dorota Iwaszkiewicz-Grześ, Elmar Jaeckel, Irma Joosten, David Klatzmann, Hans Koenen, Cees van Kooten, Olle Korsgren, Olle Korsgren, Karsten Kretschmer, Karsten Kretschmer, Megan Levings, Natalia Maria Marek-Trzonkowska, Marc Martinez-Llordella, Djordje Miljkovic, Kingston H.G. Mills, Joana P. Miranda, Ciriaco A. Piccirillo, Amy L. Putnam, Thomas Ritter, Maria Grazia Roncarolo, Shimon Sakaguchi, Silvia Sánchez-Ramón, Birgit Sawitzki, Ljiljana Sofronic-Milosavljevic, Megan Sykes, Qizhi Tang, Marta Vives-Pi, Herman Waldmann, Piotr Witkowski, Kathryn J. Wood, Silvia Gregori, Catharien M. U. Hilkens, Giovanna Lombardi, Phillip Lord, Eva M. Martinez-Caceres, Piotr Trzonkowski
Published 2018-01-01