Acid ceramidase deficiency: Farber disease and SMA-PME

by Fabian P. S. Yu, Samuel Amintas, Thierry Levade, Jeffrey A. Medin
Published 2018-07-01

The engineered thymidylate kinase (TMPK)/AZT enzyme-prodrug axis offers efficient bystander cell killing for suicide gene therapy of cancer.

by Takeya Sato, Anton Neschadim, Arnon Lavie, Teruyuki Yanagisawa, Jeffrey A Medin
Published 2013-01-01

Azidothymidine-triphosphate impairs mitochondrial dynamics by disrupting the quality control system

by Ryosuke Nomura, Takeya Sato, Yuka Sato, Jeffrey A. Medin, Shigeki Kushimoto, Teruyuki Yanagisawa
Published 2017-10-01

Development of Novel Immunotherapies for Multiple Myeloma

by Ensaf M. Al-Hujaily, Robyn A. A. Oldham, Parameswaran Hari, Jeffrey A. Medin
Published 2016-09-01

Anti-leukemia activity of in vitro-expanded human gamma delta T cells in a xenogeneic Ph+ leukemia model.

by Gabrielle M Siegers, Tania C Felizardo, A Mark Mathieson, Yoko Kosaka, Xing-Hua Wang, Jeffrey A Medin, Armand Keating
Published 2011-01-01

Sarcoma IL-12 overexpression facilitates NK cell immunomodulation

by Mary Jo Rademacher, Anahi Cruz, Mary Faber, Robyn A. A. Oldham, Dandan Wang, Jeffrey A. Medin, Nathan J. Schloemer
Published 2021-04-01

Neuraminidase 1 activates insulin receptor and reverses insulin resistance in obese mice

by Anne Fougerat, Xuefang Pan, Victoria Smutova, Nikolaus Heveker, Christopher W. Cairo, Tarik Issad, Bruno Larrivée, Jeffrey A. Medin, Alexey V. Pshezhetsky
Published 2018-06-01

Preclinical validation: LV/IL-12 transduction of patient leukemia cells for immunotherapy of AML

by Ju Huang, Yuanfeng Liu, Bryan C Au, Dwayne L Barber, Andrea Arruda, Axel Schambach, Michael Rothe, Mark D Minden, Christopher J Paige, Jeffrey A Medin
Published 2016-01-01

Interleukin-15 in cancer immunotherapy: IL-15 receptor complex versus soluble IL-15 in a cancer cell-delivered murine leukemia model

by Alexandra Berger, Sarah J. Colpitts, Melanie S. S. Seabrook, Caren L. Furlonger, Maura B. Bendix, Joshua M. Moreau, William M. McKillop, Jeffrey A. Medin, Christopher J. Paige
Published 2019-12-01

Direct Lymph Node Vaccination of Lentivector/Prostate-Specific Antigen is Safe and Generates Tissue-Specific Responses in Rhesus Macaques

by Bryan C. Au, Chyan-Jang Lee, Orlay Lopez-Perez, Warren Foltz, Tania C. Felizardo, James C.M. Wang, Ju Huang, Xin Fan, Melissa Madden, Alyssa Goldstein, David A. Jaffray, Badru Moloo, J. Andrea McCart, Jeffrey A. Medin
Published 2016-02-01

Lentivector Iterations and Pre-Clinical Scale-Up/Toxicity Testing: Targeting Mobilized CD34+ Cells for Correction of Fabry Disease

by Ju Huang, Aneal Khan, Bryan C. Au, Dwayne L. Barber, Lucía López-Vásquez, Nicole L. Prokopishyn, Michel Boutin, Michael Rothe, Jack W. Rip, Mona Abaoui, Murtaza S. Nagree, Shaalee Dworski, Axel Schambach, Armand Keating, Michael L. West, John Klassen, Patricia V. Turner, Sandra Sirrs, C. Anthony Rupar, Christiane Auray-Blais, Ronan Foley, Jeffrey A. Medin
Published 2017-06-01

Lentivirus-mediated gene therapy for Fabry disease

by Aneal Khan, Dwayne L. Barber, Ju Huang, C. Anthony Rupar, Jack W. Rip, Christiane Auray-Blais, Michel Boutin, Pamela O’Hoski, Kristy Gargulak, William M. McKillop, Graeme Fraser, Syed Wasim, Kaye LeMoine, Shelly Jelinski, Ahsan Chaudhry, Nicole Prokopishyn, Chantal F. Morel, Stephen Couban, Peter R. Duggan, Daniel H. Fowler, Armand Keating, Michael L. West, Ronan Foley, Jeffrey A. Medin
Published 2021-02-01