Carbamates as Potential Prodrugs and a New Warhead for HDAC Inhibition

by Kristina King, Alexander-Thomas Hauser, Jelena Melesina, Wolfgang Sippl, Manfred Jung
Published 2018-02-01

2-Benzazolyl-4-Piperazin-1-Ylsulfonylbenzenecarbohydroxamic Acids as Novel Selective Histone Deacetylase-6 Inhibitors with Antiproliferative Activity.

by Lei Wang, Marina Kofler, Gerald Brosch, Jelena Melesina, Wolfgang Sippl, Elisabeth D Martinez, Johnny Easmon
Published 2015-01-01

A Novel Class of Schistosoma mansoni Histone Deacetylase 8 (HDAC8) Inhibitors Identified by Structure-Based Virtual Screening and In Vitro Testing

by Conrad V. Simoben, Dina Robaa, Alokta Chakrabarti, Karin Schmidtkunz, Martin Marek, Julien Lancelot, Srinivasaraghavan Kannan, Jelena Melesina, Tajith B. Shaik, Raymond J. Pierce, Christophe Romier, Manfred Jung, Wolfgang Sippl
Published 2018-03-01