Plasmodium falciparum parasites are killed by a transition state analogue of purine nucleoside phosphorylase in a primate animal model.

by María B Cassera, Keith Z Hazleton, Emilio F Merino, Nicanor Obaldia, Meng-Chiao Ho, Andrew S Murkin, Richard DePinto, Jemy A Gutierrez, Steven C Almo, Gary B Evans, Yarlagadda S Babu, Vern L Schramm
Published 2011-01-01

Pharmacologic inhibition of ketohexokinase prevents fructose-induced metabolic dysfunction

by Jemy A. Gutierrez, Wei Liu, Sylvie Perez, Gang Xing, Gabriele Sonnenberg, Kou Kou, Matt Blatnik, Richard Allen, Yan Weng, Nicholas B. Vera, Kristin Chidsey, Arthur Bergman, Veena Somayaji, Collin Crowley, Michelle F. Clasquin, Anu Nigam, Melissa A. Fulham, Derek M. Erion, Trenton T. Ross, William P. Esler, Thomas V. Magee, Jeffrey A. Pfefferkorn, Kendra K. Bence, Morris J. Birnbaum, Gregory J. Tesz
Published 2021-06-01