Transition state analogue of MTAP extends lifespan of APCMin/+ mice

by Ross S. Firestone, Mu Feng, Indranil Basu, Karina Peregrina, Leonard H. Augenlicht, Vern L. Schramm
Published 2021-04-01

Immucillins ImmA and ImmH Are Effective and Non-toxic in the Treatment of Experimental Visceral Leishmaniasis.

by Elisangela Oliveira Freitas, Dirlei Nico, Marcus Vinícius Alves-Silva, Alexandre Morrot, Keith Clinch, Gary B Evans, Peter C Tyler, Vern L Schramm, Clarisa B Palatnik-de-Sousa
Published 2015-12-01

Immucillins Impair Leishmania (L.) infantum chagasi and Leishmania (L.) amazonensis Multiplication In Vitro.

by Elisangela Oliveira Freitas, Dirlei Nico, Rong Guan, José Roberto Meyer-Fernandes, Keith Clinch, Gary B Evans, Peter C Tyler, Vern L Schramm, Clarisa B Palatnik-de-Sousa
Published 2015-01-01

Plasmodium falciparum parasites are killed by a transition state analogue of purine nucleoside phosphorylase in a primate animal model.

by María B Cassera, Keith Z Hazleton, Emilio F Merino, Nicanor Obaldia, Meng-Chiao Ho, Andrew S Murkin, Richard DePinto, Jemy A Gutierrez, Steven C Almo, Gary B Evans, Yarlagadda S Babu, Vern L Schramm
Published 2011-01-01