Heterodimeric IL-15 delays tumor growth and promotes intratumoral CTL and dendritic cell accumulation by a cytokine network involving XCL1, IFN-γ, CXCL9 and CXCL10

by George N Pavlakis, Antonio Valentin, Jenifer Bear, Barbara K Felber, Hrishikesh Pandit, Bethany A Nagy, Maggie Cam
Published 2020-06-01

Scalable, cGMP-compatible purification of extracellular vesicles carrying bioactive human heterodimeric IL-15/lactadherin complexes

by Dionysios C. Watson, Bryant C. Yung, Cristina Bergamaschi, Bhabadeb Chowdhury, Jenifer Bear, Dimitris Stellas, Aizea Morales-Kastresana, Jennifer C. Jones, Barbara K. Felber, Xiaoyuan Chen, George N. Pavlakis
Published 2018-12-01

Systemic IL-15, IFN-γ, and IP-10/CXCL10 signature associated with effective immune response to SARS-CoV-2 in BNT162b2 mRNA vaccine recipients

by Cristina Bergamaschi, Evangelos Terpos, Margherita Rosati, Matthew Angel, Jenifer Bear, Dimitris Stellas, Sevasti Karaliota, Filia Apostolakou, Tina Bagratuni, Dimitris Patseas, Sentiljana Gumeni, Ioannis P. Trougakos, Meletios A. Dimopoulos, Barbara K. Felber, George N. Pavlakis
Published 2021-08-01

Treatment with native heterodimeric IL-15 increases cytotoxic lymphocytes and reduces SHIV RNA in lymph nodes.

by Dionysios C Watson, Eirini Moysi, Antonio Valentin, Cristina Bergamaschi, Santhi Devasundaram, Sotirios P Fortis, Jenifer Bear, Elena Chertova, Julian Bess, Ray Sowder, David J Venzon, Claire Deleage, Jacob D Estes, Jeffrey D Lifson, Constantinos Petrovas, Barbara K Felber, George N Pavlakis
Published 2018-02-01

Correction: Treatment with native heterodimeric IL-15 increases cytotoxic lymphocytes and reduces SHIV RNA in lymph nodes.

by Dionysios C Watson, Eirini Moysi, Antonio Valentin, Cristina Bergamaschi, Santhi Devasundaram, Sotirios P Fortis, Jenifer Bear, Elena Chertova, Julian Bess, Ray Sowder, David J Venzon, Claire Deleage, Jacob D Estes, Jeffrey D Lifson, Constantinos Petrovas, Barbara K Felber, George N Pavlakis
Published 2018-10-01

DNA and protein co-immunization improves the magnitude and longevity of humoral immune responses in macaques.

by Rashmi Jalah, Viraj Kulkarni, Vainav Patel, Margherita Rosati, Candido Alicea, Jenifer Bear, Lei Yu, Yongjun Guan, Xiaoying Shen, Georgia D Tomaras, Celia LaBranche, David C Montefiori, Rajasekhar Prattipati, Abraham Pinter, Julian Bess, Jeffrey D Lifson, Steven G Reed, Niranjan Y Sardesai, David J Venzon, Antonio Valentin, George N Pavlakis, Barbara K Felber
Published 2014-01-01

Kinetics of Nucleocapsid, Spike and Neutralizing Antibodies, and Viral Load in Patients with Severe COVID-19 Treated with Convalescent Plasma

by Thomas P. Thomopoulos, Margherita Rosati, Evangelos Terpos, Dimitris Stellas, Xintao Hu, Sevasti Karaliota, Anthi Bouchla, Ioannis Katagas, Anastasia Antoniadou, Andreas Mentis, Sotirios G. Papageorgiou, Marianna Politou, Jenifer Bear, Duncan Donohue, Anastasia Kotanidou, Ioannis Kalomenidis, Eleni Korompoki, Robert Burns, Maria Pagoni, Elisavet Grouzi, Stavroula Labropoulou, Kostantinos Stamoulis, Aristotelis Bamias, Sotirios Tsiodras, Meletios-Athanasios Dimopoulos, George N. Pavlakis, Vasiliki Pappa, Barbara K. Felber
Published 2021-09-01

A Phase II Study on the Use of Convalescent Plasma for the Treatment of Severe COVID-19- A Propensity Score-Matched Control Analysis

by Vasiliki Pappa, Anthi Bouchla, Evangelos Terpos, Thomas P. Thomopoulos, Margherita Rosati, Dimitris Stellas, Anastasia Antoniadou, Andreas Mentis, Sotirios G. Papageorgiou, Marianna Politou, Anastasia Kotanidou, Ioannis Kalomenidis, Garyfalia Poulakou, Edison Jahaj, Eleni Korompoki, Sotiria Grigoropoulou, Xintao Hu, Jenifer Bear, Sevasti Karaliota, Robert Burns, Maria Pagoni, Ioannis Trontzas, Elisavet Grouzi, Stavroula Labropoulou, Kostantinos Stamoulis, Aristotelis Bamias, Sotirios Tsiodras, Barbara K. Felber, George N. Pavlakis, Meletios- Athanasios Dimopoulos
Published 2021-04-01

Anti–SARS-CoV-2 Antibody Responses in Convalescent Plasma Donors Are Increased in Hospitalized Patients; Subanalyses of a Phase 2 Clinical Study

by Evangelos Terpos, Marianna Politou, Theodoros N Sergentanis, Andreas Mentis, Margherita Rosati, Dimitris Stellas, Jenifer Bear, Xintao Hu, Barbara K. Felber, Vassiliki Pappa, Maria Pagoni, Elisavet Grouzi, Stavroula Labropoulou, Ioanna Charitaki, Ioannis Ntanasis-Stathopoulos, Dimitra Moschandreou, Anthi Bouhla, Stylianos Saridakis, Eleni Korompoki, Chara Giatra, Tina Bagratuni, Angelos Pefanis, Sotirios Papageorgiou, Alexandros Spyridonidis, Anastasia Antoniadou, Anastasia Kotanidou, Konstantinos Syrigos, Konstantinos Stamoulis, George Panayiotakopoulos, Sotirios Tsiodras, Leonidas Alexopoulos, Meletios A Dimopoulos, George N. Pavlakis
Published 2020-11-01