HIV DNA Vaccine: Stepwise Improvements Make a Difference

by Barbara K. Felber, Antonio Valentin, Margherita Rosati, Cristina Bergamaschi, George N. Pavlakis
Published 2014-05-01

Viral infection increases glucocorticoid-induced interleukin-10 production through ERK-mediated phosphorylation of the glucocorticoid receptor in dendritic cells: potential clinica...

by Sinnie Sin Man Ng, Andrew Li, George N Pavlakis, Keiko Ozato, Tomoshige Kino
Published 2013-01-01

Heterodimeric IL-15 in Cancer Immunotherapy

by Cristina Bergamaschi, Vasiliki Stravokefalou, Dimitris Stellas, Sevasti Karaliota, Barbara K. Felber, George N. Pavlakis
Published 2021-02-01

Temporal Dominance of B.1.1.7 over B.1.354 SARS-CoV-2 Variant: A Hypothesis Based on Areas of Variant Co-Circulation

by Evangelia Georgia Kostaki, Ioulia Tseti, Sotirios Tsiodras, George N. Pavlakis, Petros P. Sfikakis, Dimitrios Paraskevis
Published 2021-04-01

Heterodimeric IL-15 delays tumor growth and promotes intratumoral CTL and dendritic cell accumulation by a cytokine network involving XCL1, IFN-γ, CXCL9 and CXCL10

by George N Pavlakis, Antonio Valentin, Jenifer Bear, Barbara K Felber, Hrishikesh Pandit, Bethany A Nagy, Maggie Cam
Published 2020-06-01

HIV-1 conserved elements p24CE DNA vaccine induces humoral immune responses with broad epitope recognition in macaques.

by Viraj Kulkarni, Antonio Valentin, Margherita Rosati, Morgane Rolland, James I Mullins, George N Pavlakis, Barbara K Felber
Published 2014-01-01

The Emerging Role of Convalescent Plasma in the Treatment of COVID-19

by Theodora Psaltopoulou, Theodoros N. Sergentanis, Vasiliki Pappa, Marianna Politou, Evangelos Terpos, Sotirios Tsiodras, George N. Pavlakis, Meletios A. Dimopoulos
Published 2020-06-01

Evaluation of chimeric antigen receptor T cell therapy in non-human primates infected with SHIV or SIV.

by Nami Iwamoto, Bhavik Patel, Kaimei Song, Rosemarie Mason, Sara Bolivar-Wagers, Cristina Bergamaschi, George N Pavlakis, Edward Berger, Mario Roederer
Published 2021-01-01

Insights to SARS-CoV-2 life cycle, pathophysiology, and rationalized treatments that target COVID-19 clinical complications

by Ioannis P. Trougakos, Kimon Stamatelopoulos, Evangelos Terpos, Ourania E. Tsitsilonis, Evmorfia Aivalioti, Dimitrios Paraskevis, Efstathios Kastritis, George N. Pavlakis, Meletios A. Dimopoulos
Published 2021-01-01

Scalable, cGMP-compatible purification of extracellular vesicles carrying bioactive human heterodimeric IL-15/lactadherin complexes

by Dionysios C. Watson, Bryant C. Yung, Cristina Bergamaschi, Bhabadeb Chowdhury, Jenifer Bear, Dimitris Stellas, Aizea Morales-Kastresana, Jennifer C. Jones, Barbara K. Felber, Xiaoyuan Chen, George N. Pavlakis
Published 2018-12-01

Systemic IL-15, IFN-γ, and IP-10/CXCL10 signature associated with effective immune response to SARS-CoV-2 in BNT162b2 mRNA vaccine recipients

by Cristina Bergamaschi, Evangelos Terpos, Margherita Rosati, Matthew Angel, Jenifer Bear, Dimitris Stellas, Sevasti Karaliota, Filia Apostolakou, Tina Bagratuni, Dimitris Patseas, Sentiljana Gumeni, Ioannis P. Trougakos, Meletios A. Dimopoulos, Barbara K. Felber, George N. Pavlakis
Published 2021-08-01

Altered response hierarchy and increased T-cell breadth upon HIV-1 conserved element DNA vaccination in macaques.

by Viraj Kulkarni, Antonio Valentin, Margherita Rosati, Candido Alicea, Ashish K Singh, Rashmi Jalah, Kate E Broderick, Niranjan Y Sardesai, Sylvie Le Gall, Beatriz Mothe, Christian Brander, Morgane Rolland, James I Mullins, George N Pavlakis, Barbara K Felber
Published 2014-01-01

Treatment with native heterodimeric IL-15 increases cytotoxic lymphocytes and reduces SHIV RNA in lymph nodes.

by Dionysios C Watson, Eirini Moysi, Antonio Valentin, Cristina Bergamaschi, Santhi Devasundaram, Sotirios P Fortis, Jenifer Bear, Elena Chertova, Julian Bess, Ray Sowder, David J Venzon, Claire Deleage, Jacob D Estes, Jeffrey D Lifson, Constantinos Petrovas, Barbara K Felber, George N Pavlakis
Published 2018-02-01

Correction: Treatment with native heterodimeric IL-15 increases cytotoxic lymphocytes and reduces SHIV RNA in lymph nodes.

by Dionysios C Watson, Eirini Moysi, Antonio Valentin, Cristina Bergamaschi, Santhi Devasundaram, Sotirios P Fortis, Jenifer Bear, Elena Chertova, Julian Bess, Ray Sowder, David J Venzon, Claire Deleage, Jacob D Estes, Jeffrey D Lifson, Constantinos Petrovas, Barbara K Felber, George N Pavlakis
Published 2018-10-01

Labeling Extracellular Vesicles for Nanoscale Flow Cytometry

by Aizea Morales-Kastresana, Bill Telford, Thomas A. Musich, Katherine McKinnon, Cassandra Clayborne, Zach Braig, Ari Rosner, Thorsten Demberg, Dionysios C. Watson, Tatiana S. Karpova, Gordon J. Freeman, Rosemarie H. DeKruyff, George N. Pavlakis, Masaki Terabe, Marjorie Robert-Guroff, Jay A. Berzofsky, Jennifer C. Jones
Published 2017-05-01

An inducible and reversible mouse genetic rescue system.

by Hongkui Zeng, Kyoji Horie, Linda Madisen, Maria N Pavlova, Galina Gragerova, Alex D Rohde, Brian A Schimpf, Yuqiong Liang, Ethan Ojala, Farah Kramer, Patricia Roth, Olga Slobodskaya, Io Dolka, Eileen A Southon, Lino Tessarollo, Karin E Bornfeldt, Alexander Gragerov, George N Pavlakis, George A Gaitanaris
Published 2008-05-01

HIV-1 p24(gag) derived conserved element DNA vaccine increases the breadth of immune response in mice.

by Viraj Kulkarni, Margherita Rosati, Antonio Valentin, Brunda Ganneru, Ashish K Singh, Jian Yan, Morgane Rolland, Candido Alicea, Rachel Kelly Beach, Gen-Mu Zhang, Sylvie Le Gall, Kate E Broderick, Niranjan Y Sardesai, David Heckerman, Beatriz Mothe, Christian Brander, David B Weiner, James I Mullins, George N Pavlakis, Barbara K Felber
Published 2013-01-01

DNA and protein co-immunization improves the magnitude and longevity of humoral immune responses in macaques.

by Rashmi Jalah, Viraj Kulkarni, Vainav Patel, Margherita Rosati, Candido Alicea, Jenifer Bear, Lei Yu, Yongjun Guan, Xiaoying Shen, Georgia D Tomaras, Celia LaBranche, David C Montefiori, Rajasekhar Prattipati, Abraham Pinter, Julian Bess, Jeffrey D Lifson, Steven G Reed, Niranjan Y Sardesai, David J Venzon, Antonio Valentin, George N Pavlakis, Barbara K Felber
Published 2014-01-01

CTL responses of high functional avidity and broad variant cross-reactivity are associated with HIV control.

by Beatriz Mothe, Anuska Llano, Javier Ibarrondo, Jennifer Zamarreño, Mattia Schiaulini, Cristina Miranda, Marta Ruiz-Riol, Christoph T Berger, M José Herrero, Eduard Palou, Montse Plana, Morgane Rolland, Ashok Khatri, David Heckerman, Florencia Pereyra, Bruce D Walker, David Weiner, Roger Paredes, Bonaventura Clotet, Barbara K Felber, George N Pavlakis, James I Mullins, Christian Brander
Published 2012-01-01

Kinetics of Nucleocapsid, Spike and Neutralizing Antibodies, and Viral Load in Patients with Severe COVID-19 Treated with Convalescent Plasma

by Thomas P. Thomopoulos, Margherita Rosati, Evangelos Terpos, Dimitris Stellas, Xintao Hu, Sevasti Karaliota, Anthi Bouchla, Ioannis Katagas, Anastasia Antoniadou, Andreas Mentis, Sotirios G. Papageorgiou, Marianna Politou, Jenifer Bear, Duncan Donohue, Anastasia Kotanidou, Ioannis Kalomenidis, Eleni Korompoki, Robert Burns, Maria Pagoni, Elisavet Grouzi, Stavroula Labropoulou, Kostantinos Stamoulis, Aristotelis Bamias, Sotirios Tsiodras, Meletios-Athanasios Dimopoulos, George N. Pavlakis, Vasiliki Pappa, Barbara K. Felber
Published 2021-09-01